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Hsa_circ_0009910 Regulates Cisplatin Sensitivity of Ovarian Cancer Cells by Targeting miR-455-5p /PAX2

Hsa_circ_0009910 Regulates Cisplatin Sensitivity of Ovarian Cancer Cells by Targeting miR-455-5p /PAX2

Lei Jiang, Yi Huang, Runfeng Yang, Xiaohui Jiang* and Hao Yan

Gynomaceae, Hubei Cancer Hospital, Wuhan, 430079, China

 
* Corresponding author: dr.med.jiang@gmail.com

Fig. 1.

Western bolt analysis of expression of PAX2 protein in HOSEPiCs, SKOV3 and SKOV3/DDP cell lines.

Fig. 2.
Effect of circ_0009910 knockout on viability and apoptosis of SKOV3/DDP.
Note: A, CCK8 detects the cell sensitivity to cisplatin; B, Flow cytometry detects cell apoptosis; C, Western bolt detects apoptosis-related protein expression.
Fig. 4.

Western bolt detection of PAX2 protein expression.

Fig. 5.
Western bolt detection of apoptosis-related protein expression.
Fig. 3.
Effect of overexpression of miR-455-5p viability and apoptosis of SKOV3/DDP.
Note: A, CCK8 detects cell sensitivity to cisplatin; B, Flow cytometry detects cell apoptosis; C, Western bolt detects apoptosis-related protein expression.

Pakistan Journal of Zoology

April

Pakistan J. Zool., Vol. 56, Iss. 2, pp. 503-1000

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