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Mudasir Irfan Dar*, Fareed Ahmad Khan and Farha Rehman

E-mail | irfanmudasir@gmail.com

...roline, ascorbate (ASC), glutathione (GLU), antioxidative enzymes; superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX) and glutathione reductase (GR) were assessed. Imidacloprid enhanced malondi- aldehyde (MDA) and proline contents over their respective controls at all doses and growth stages observed, attaining maximum with 40 grams Imidacloprid active ingredient per hectare-1 at day 15 after treatment. T...

Laila M. Fadda1, Nouf M. Al-Rasheed1, Iman H. Hasan1, Hanaa M. Ali2,3*, Nawal M. Al-Rasheed1,4, Musaed Al-Fayez5, Aly M. Ahmed5, Nada Almutlaq1, Nehal Qasem1 and Reem Khalaf1

...(APAP) overdose depleted glutathione (GSH) which lead to liver dysfunction and hence hepatotoxicity. N-acetylcysteine (NAC) is the best antidote for APAP but may induce a variety of side effects. This study was designed to compare the potential impact of NAC with that of Thymoquinone (THQ), and/or Curcumin (CUR) either alone or in combination on liver injury induced by inflammation, oxidative stress in response to APAP toxicity in rats. Serum aminotransferases...

G.E. Odo1*, E.J. Agwu1, N.I. Ossai2, C.O. Ezea3, J. Madu1 and V. Eneje2

...oxide dismutase, reduced glutathione, alkaline phosphatase (ALP), alanine aminotransferase (AST) and aspartate aminotransferase (AST). Similarly, aluminium phosphide enhanced levels of AST, ALT and ALP as both concentration and time dependent in elevation were recorded when compared to the control. The use of aluminium phosphide in agricultural fields near water bodies should be strongly monitored in view of the observed effects on this catfish fish physiology...
Sidra Ilyas1, Abdul Rehman1* and Qasim Ilyas2
...a remarkable increase in glutathione (GSH) level after As and Pb treatment in contrast to Cd, Cr and Cu exposure. GSH: GSSG ratio declined after As, Pb and Cr treatment, whereas non-protein thiol levels were higher after Cd and As treatment followed by those of Pb, Cr and Cu treatment. Candida sp. PS33 was able to remove 78% (Cd), 70% (As), 82% (Cu), 65% (Cr) and 87% (Pb) from the medium after 8 days of incubation. This multi-resistant yeast can be used...
Baohua Chen1,2, Wenzhu Peng3, Jian Xu2, Jingyan Feng1,2, Chuanju Dong1,2 and Peng Xu2,3,*

Furukh Faiz1,2, Muhammad Issa Khan2, Masood Sadiq2 and Haq Nawaz3

... dismutase, catalase and glutathione peroxidase in the broiler blood was increased as the citrus waste level in the feed of the broilers was increased. The citrus waste addition in the feed of the broiler have non-significant effects on the growth parameters, however it has positive effects on the antioxidant enzymes profile of the broilers.

...
Farid S. Ataya,1,2,* Dalia Fouad,3,4 Ajamaluddin Malik,1 Nikolaos E. Labrou,5 Mohamed S. Daoud1,6 and Hesham M. Saeed7
... characterization of the glutathione transferase isoenzyme P1-1 gene from Camelus dromedarius (CdGSTP1-1). The coding sequence was cloned using RT-PCR. Sequence analysis demonstrated significant differences between amino acid sequence of C. dromedarius and other mammalian GSTP1-1 enzymes. Phylogenetic relationship was studied with different organisms belonging to animal kingdom and revealed that CdGSTP1-1 is grouped with the enzyme ...

Soraya Khosravian Dehordi*, Abdolnaser Mohebbi and Kahin Shahanipour

...peroxide dismutase (SOD) glutathione peroxidase (GPx) and catalase (CAT) values in spleen were measured. An increase in TBARS and PC levels was obtained in rats' spleen of the Cd-group than controls and nano-Se decreased this effect close to the control. The CAT values of all groups did not differ significantly. The values of SOD and GPx were reduced in splenic tissue of Cd-intoxicated rats, but the nano-Se was able improve these undesirable effects. However, ...
Zhiping Hu, Hussain Ahmad, Jingfei Zhang, Lili Zhang and Tian Wang*
... CON group at 21d. Serum glutathione peroxidase enzyme activity was significantly increased in T1 group compared to CON group at 42d. Malondialdehyde content of liver in T1 group was lower than that of CON group. These results suggested that dietary supplementation of 10 mg/kg natamycin had a positive influence in broilers.
...
Kaori Sasaoka1, Takahiro Kataoka1, Norie Kanzaki1, Yusuke Kobashi1, Akihiro Sakoda2, Yuu Ishimori2 and Kiyonori Yamaoka1,*
...t contents (catalase and glutathione). When BALB/c mice were treated with a lower dose of CDDP (15 mg/kg) after 1000 Bq/m3 radon inhalation, the creatinine level was reduced and the superoxide dismutase content was increased, suggesting that this combination might have a protective effect against the CDDP-induced renal damage. The supportive effect of radon inhalation shows its good potential as a candidate treatment to alleviate CDDP-induced renal ...
Tayfun Karataş
...the hepatic catalase and glutathione peroxidase (p<0.05). In muscle tissue, the TBARS levels were significantly decreased (p<0.05). Whereas, antioxidant enzyme activities remained unchanged (p>0.05). The results obtained from this study showed that the short-term starvation leads to significant changes on serum metabolites, antioxidant enyzme activities and endogenous reserves of rainbow trout.
...
Song Jiang1,2, Fa-lin Zhou1, Qi-bin Yang1, Jian-hua Huang1, Li-shi Yang1 and Shi-gui Jiang1*
...ismutase (SOD) activity, glutathione (GSH) and adenosine triphosphate (ATP) concentration, as well as nitric oxide synthase (NOS) activity and nitric oxide (NO) concentration catalyzed by NOS. Based on biochemical analysis of the above, results showed that O2- production could be induced significantly after cold stress at 15°C and heat stress above 30°C. SOD activity showed a similar changing profile as the concentration of O...
Asima Bano1, Hafiz Muhammad Tahir2, Hira Sherawat3, Muhammad Mutlib4, Muhammad Arshad5, Muhammad Akram Qazi6, Sajida Naseem5, Rabia Ishaq1, Iram Liaqat2 
Tünay Kontaş Aşkar1,*, Şinasi Aşkar1, Olga Büyükleblebici2 and Murat Güzel3
...al antioxidant capacity, glutathione, nitric oxide, myeloperoxidase, adenosine deaminase and cytokines (TNF-alpha, IL-1β) were determined and compared with the healthy controls. Significantly high levels of plasma malondialdehyde, nitric oxide, myeloperoxidase, adenosine deaminase and cytokines and significantly low levels in total antioxidant capacity and glutathione levels were found in dogs with leishmaniasis when co...
A.M. Abdul Azeem, A.N. El Shahat* and Ashraf M. Mounir
...antioxidant capacity and glutathione content and the activity of superoxide dismutase activity and catalase activity of the liver and testes of lead-intoxicated rats. In conclusion GPE could ameliorate the damage and apoptotic effects occurred by exposure to toxic dose of lead.
...
Iqra Bano1,*, Moolchand Malhi2, Pershotam Khatri3, Saeed Ahmed Soomro2, Hira Sajjad4, Ambreen Leghari5, Muhammad Awais2, Safia Kandhro6 and Shakeel Ahmed Lakho5 and Munaza Soomro7
...n both groups. The serum glutathione peroxidase (GPx) activity as well the testicular GPx activity was significantly increased in SY as compared to C. Furthermore, the serum T-SOD activity was significantly elevated in SY as compared to C. Moreover, the T-SOD activity in testicular tissues was also significantly increased in SY as compared to C. The results revealed that the SY supplementation has positive effects on gross morphological parameters of testis by...

 Şaban Çelebi

...and enzyme activities of glutathioneperoxidase (GSH-Px), superoxide dismutase (SOD) and catalase (CAT) in liver, heart, breast and thigh tissues of laying hens were determined in present study. A total of 96 White Lohman laying hens, aged 24 weeks, were randomly divided into 4 groups (n=24), each of which was composed of 6 subgroups. The control group received the basal diet (T-1), treatment groups were fed on the the basal diet plus the three experimental die...

 Mahroze Fatima1*, Muhammad Afzal2 and Syed Zakir Hussain Shah3

...tase (SOD), catalase and glutathione peroxidase activities, which were increased by feeding high vitamin dosages. Supplementation of vitamin E decreased the saturated fatty acids (SFA) and monoenes while increased the poly unsaturated fatty acids (PUFA) compared to control group. Similarly, eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), docosahexanoic acid (DHA), total n-3 PUFA and total n-6 PUFA, arachidonic acid (ARA)/EPA, EPA/DHA, n3/n6 ratios we...
Huma Naz1,*, Sajid Abdullah2, Khalid Abbas2, Wardah Hassan3, Moazama Batool4, Shakeela Perveen5, Sadia Maalik4 and Sajida Mushtaq4
...peroxidase, catalase and glutathione S-transferase in different organs (liver, gills, kidney, brain, heart and muscle) of fish, Labeo rohita. The LC50 of chlorpyrifos+endosulfan mixture was calculated as 1.95±0.02 μgL-1 for 96 h with the 95% confidence limits. The fish expose to the mixture (1:1) for 96-h. The results obtained from this study showed that superoxide dismutase, peroxidase and glutat...
Ailing Huang, Lingyu Meng, Wei Zhang, Junyan Liu, Guangyao Li, Huihua Tan, Wen Lu and Xialin Zheng*
... pesticides; activity of glutathione-s transferase (GST) was inhibited by abamectin, while the trend was in the opposite direction for other four pesticides; activity of superoxide dismutase (SOD) was promoted by beta-cypermethrin and chlorpyrifos, and inhibited by abamectin and bisultap; Activity of catalase (CAT) was promoted by beta-cypermethrin, chlorpyrifos and bisultap, inhibited the influence of promotion by thiamethoxam. Results suggested that P. fl...
Sheng Niu1, Ali-Raza Jahejo1, Fa-jie Jia1, Xin Li1, Guan-bao Ning1, Ding Zhang1, Hai-li Ma1, Wei-fang Hao2, Wen-wei Gao1, Yu-jun Zhao1, Shi-min Gao1, Jian-hui Li1, Gui-lan Li1, Fang Yan1, Rong-kun Gao1, Huan-chun Chen1,3 and Wen-xia Tian1,*
...ent doses of recombinant glutathione-S-transferase A3 (rGSTA3) proteins. We explored the responses of HDPs in erythrocytes to thiram-induced TD and rGSTA3 protein by quantitative real time PCR (qRT-PCR). The results showed many HDPs expressions were suppressed by thiram-induced TD, and the expressions of HDPs were upregulated by rGSTA3 protein. These findings demonstrated that mRNA expressions of HDPs are highly related to thiram-induced TD, and rGSTA3 protein...
Iqra Jaffar, Zainab Sehzadi, Muhammad Adeel, Khalid P. Lone and Mehwish Faheem*
...by analyzing activity of glutathione-S-transferase (GST), catalase (CAT), glutathione (GSH) and by measuring lipid peroxidation (LPO). Catalase activity increased significantly in liver and gills of fish exposed to 10μg/l of DBP. Level of GSH and LPO increased significantly in gills while a non-significant decrease was recorded for GSH and GST in liver. These results showed that exposure to low concentrations of di-n-buty...
Muhammad Naveed Sheas1, Haris Rasool2, Muhammad Nouman Rafique2, Muhammad Rizwan Tariq1*, Abid Muhammad1, Khubaib Ali1
Uzma Jabeen1, Irfan Khan2, Nadia Naeem2, Asmat Salim2,* and Waseem Ahmed1
... dehydrogenase 1 (Nqo1), glutathione peroxidase (Gpx1) and isocitrate dehydrogenase-1 (Idh1) were analyzed by RT-PCR. We observedvariable pattern of gene expression was observed. Nqo1 and Idh1 genes were upregulated significantly in heart but not in liver tissue. Gpx1 seems to be unaffected both in heart and liver tissues. It is concluded from this study that toxicity due to doxorubicin is variable in terms of expression of certain oxidative stress induced gen...
Zeynep Soyer Sarıca1*, Meryem Eren2 and Meryem Senturk2
...SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) enzymes were estimated in the brain tissues of the Sprague Dawley rats. Compared to the control groups, a significant increase in the brain tissue MDA level of the group which received only 10 mg/kg K2Cr2O7 was observed, whereas no statistically significant change was detected in SOD, CAT and GSH-Px enzyme activities. It was further observed that after administration of B...
Mo Chen1, Shad Mahfuz1, 2, Yan Cui1, Liying Jia1, Zhongjun Liu3 and Hui Song1, 4*
...) in 6%FVS than control; glutathione peroxidase (GSH-Px) was significantly higher (P<0.05) in FVS fed groups and control groups than in the antibiotic fed group; Malondialdehyde (MDA) was significantly lower (P<0.05) in FVS fed groups and antibiotic groups than in the control fed group. However, there was no significant difference were observed for serum total superoxide dismutase (T-SOD) in among experimental groups. Yolk antioxidant T-AOC and T-SOD wer...

Hala Rajab1, Muhammad Sayyar Khan1*, Safdar Hussain Shah1 and Syed Mehar Ali Shah2 

...h levels of cysteine and glutathione for enhanced stress tolerance especially against heavy metals. 

...
Hafiz Muhammad Arsalan1, Maria Altaf1, Zeemal Seemab Amin1, Muhammad Khalil Ahmad Khan2, Anum Shahzadi1, Hina Mudasser1, Iqra Maqsood1, Nazia Gulshan1, Saira Naseem3
Awais Bin Shahid1, Moolchand Malhi1,*, Saeed Ahmed Soomro1, Muhammad Giasuddin Shah2, Nazeer Hussain Kalhoro3, Asmatullah Kaka4, Rajoo Mal1, Muhammad Awais Soomro1Saba Parveen Samo1 and Muhammad Nawaz Sanjrani5
...ared to C. The glutathione peroxidase (GSH-Px) activity increased (P < 0.05) in ruminal epithelium of SY goats compared to C. The present study demonstrated an improvement in ruminal fermentation, and hyperplasia and enhanced GSH-Px activity in the ruminial epithelium of goats fed SY supplemented diet compared to control that were fed diet without SY supplementation. 
...
Sameh S. Tawfik, Ahmed A. Elkady* and Ehab T. Mohamed
...renal catalase (CAT) and glutathione peroxidase (PGx) activities and reduced-glutathione (GSH) content and significantly limited the elevation in serum tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and interleukin-6 (IL-6) levels when compared to irradiated rat group. The histopathological-findings of renal tissues in the irradiated-group, showed nephrotoxicity; the renal cortex showed massive...
Dilara Abbas Bukhari*, Mehwish Faheem, Shamoona Arshad and Khalid P. Lone
...n (LPO), catalase (CAT), glutathione-S-transferase (GST), reduced glutathione (GSH) were determined to evaluate oxidative stress while urea and creatinine, was used to evaluate kidney function. It was found that there was an increase in weight (p<0.05) of both males and female mice fed with diet containing ghee. Kidney LPO and CAT were significantly increased in both male and female mice. GSH level showed decreasing trend...
Elmas Ulutaş1,*, Abdullah Eryavuz2, Aziz Bülbül2, Abdur Rahman3,*, İsmail Küçükkurt4 and Cangir Uyarlar5
...plasma urea nitrogen and glutathione but decreased (p<0.05) leptin and malondialdehyde concentration while other parameters remained unaffected. No difference was observed in ruminal pH between the treatment groups. Ruminal ammonia and number of protozoa were decreased (p<0.05) with 700 ppm and 1000 ppm zinc supplementation. Rumen Zn concentration increased (p<0.05) in the goats fed with 1000 ppm zinc, whereas there was no difference in rumen Fe and C...
Ju Zhang1,2, Dong-Sheng Jia3, Shi-Hao Zhao1,2, Xiao-Liang Xie3, Hong Chen4 and Hai-Feng Li4,*

 

...SOD), catalase (CAT) and glutathione peroxidase (GPx) activities.We observed that HGQ exerted little effect on the growth of wild-type N2 nematodes at concentration < 0.6 mg/ml, and 0.05 mg/ml of the HGQ significantly prolonged the lifespan and reduced the lipofuscin level in N2 nematodes. However, the HGQ failed to influence the pharyngeal pumping rate in N2 nematodes or to affect the lifespan of sir-2.1 mutant nematode VC199, indicating the anti-ag...
Derya Kocamaz* and Elif Oruc
...eroxide dismutase (SOD), glutathione S-transferase (GST), glutathione (GSH) and protein carbonil (PCO) increased in comparison to the control. After the recovery period, EROD, GST, malondialdehyde, estradiol/testosterone levels were found to be lower than the control. In the pesticide mixture group, the activity of antioxidant enzymes was highest and the level of hormones was lowered. The group of the mixture pesticide showe...
Ahmet Ozer Sehirli1,2, Serkan Sayiner3*, Ayliz Velioglu-Ogunc4, Nedime Serakinci5, Emel Eksioglu-Demiralp6, Berrak Yegen7, Feriha Ercan8 andGoksel Sener2
...alondialdehyde (MDA) and glutathione (GSH) levels. A significant difference was determined between the CRF group and the control group with regard to heart rate, blood pressure, serum creatinine, BUN, LDH, cytokines and urinary electrolyte levels. Furthermore, monocyte and neutrophil apoptosis, tissue luminol, lucigenin, malondialdehyde and collagen levels were found to increase. Tissue glutathione levels were found to decre...
Lei Gao1, Gong-xue Jia2, Zheng-yuan Huang1, Ming-xing Yue3, Chao Zhang1, Shi-en Zhu1 and Xiang-wei Fu1,*
...oxygen species (ROS) and glutathione (GSH). DNA DSBs were examined by immunostaining of pi-H2AX, the marker of DNA DSBs. The results showed that the GVBD rates were similar in oocytes of young and aged mice. Polar body extrusion was significantly delayed in aged mice (P < 0.05), however the rate of polar body extrusion was similar to that of young mice at 16 h of IVM. Moreover, PN formation of parthenogenetic embryo was significantly delayed in aged mice (P...
Xuhui Zhang1, Zhiyuan Sun2, Jinfeng Cai1, Guibin Wang1, Zunling Zhu1, Linguo Zhao3 and Fuliang Cao1,*
...R3 diet. Moreover, serum glutathione (GSH) and α-tocopherol (α-TOH) contents in the FR groups were increased, while, levels of total cholesterol (TC), malondialdehyde (MDA) in serum and hepatic reactive oxygen species (ROS) in FR groups were significantly decreased compared with the control or NF group at 42 d of age. Furthermore, serum total superoxide dismutase (T-SOD) activity of birds from group FR3 was significantly increased (42d) compar...
Qaisra Siddique1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3

 

...as performed to evaluate glutathione S-transferase (GST) activityand total protein contents (TPCs) in tissues viz. brain, gills, kidney, heart, muscle and liver of Labeo rohita kept under sub-lethal dose (4.13 µgL-1) of chlorpyrifos. Fish was kept under chlorpyrifos stress for two months and samples were collected on weekly basis. It was noted that GST level varied significantly with duration. The GST level was raised in first 28 days a...
Aamir Mushtaq1,2, Rukhsana Anwar1 and Mobasher Ahmad1,2,* 
...1.42 ± 0.05 U/mg) glutathione (37.56 ± 1.89 μ mol/mg) and reduction in malondialdehyde (7.83 ± 0.21 n mol/mg) level was observed in group receiving 800mg/kg of mep.a as compared to amnesic group. Pimpinella anisum thus improved memory in mice by preventing oxidative stress in brain.
...

Haiyan Yang1, Hongxia Liu1, Wenlong Wu1*, Weilin Li2 and Lianfei Lyu

...orbate (AsA) and reduced glutathione (GSH), activities of superoxide dismutase (SOD) and peroxidase (POD) in leaves of ‘Hull Thornless’ were investigated. In the treatment group, water stress significantly increased EL, and the accumulation of photosynthetic pigments, protein, soluble sugar, H2O2 and MDA. After re-watering, all of those parameters showed decreases of different degree. LWC was significantly decreased in response to drought treatment...

Dilan Ozmen Ozgun1, Gonca Alak2, Arzu Ucar2, Sinan Bilginer3, Halise Inci Gul3, Mahmut Kocaman2, Cem Yamalı3, Veysel Parlak2, Muhammed Atamanalp2, Ahmad Maslat4 and Telat Yanık2*

...xide dismutase (SOD) and glutathione peroxidase activities were decreased, while MDA values increased significantly (p<0.05) in gill and liver of fish compared to control group. SOD activity was time dependent; it decreased initially, but then take increased. WBC, MCV, MCH and MCHC levels increased, while RBC Hb, Htc and PLT levels decreased with increasing dose from 0.25 to 2.5 mg/L of B4 (p<0.05) compared to control. There were no differences between c...
Congfen Zhang1,Yingxiao Liu2, Linfeng He2, Fengjun Shi2, Weitang Yao2 and Xuegang Luo2,*
...dehyde (MDA) and reduced glutathione (GSH) and activities of superoxide dismutase (SOD), and catalase (CAT) as well as their corresponding mRNA levels in the fat bodies of the pupae were evaluated. As a result, we found that the contents of MDA were increased at 4 h and then decreased compared with control. And, the contents of GSH were decreased gradually. However, the activities of catalase were inhibited and the trend of SOD activity changes was down-regula...

Vladimir Safonov 

...tioxidant defense enzyme glutathione peroxidase. This article examines the intensity of lipid peroxidation processes and the functioning of the antioxidant defense system in pregnant and calved cows in the area with selenium favorable agrobiocenoses (Voronezh region, Russian Federation) and selenium-deficient biogeochemical province (Kirov region, Russian Federation). The LPO-AOS parameters were evaluated in 89 Black-Motley cows at the age, corresponding to 2...

Arkan B. Mohammed*, Ammar S. Abdulwahid, Samah M. Raouf 

... significantly increased glutathione, while, decreased the malondialdehyde, AST and ALT activity in comparison to the control. Therefore, it can be concluded that thyme additives can be used in laying hens diet to improve egg production, egg quality, antioxidant and biochemical parameters in a dose-dependent manner.

 

Keywords | Antioxidants, Egg production, Laying hens, Thyme
 

...

A.M. Abdul Azeem, Ashraf M. Mounir and Amr N. El-Shahat*

... antioxidant parameters (glutathione content , the activity of xanthine dehydrogenase, superoxide dismutase and catalase) in the group of alloxan (150 mg/kg B.WT)-administrated rats as compared to control group. Treatment of diabetic rats with GPSDP (1 g/kg B.Wt/day/ 8 weeks) resulted in significant reduction of glucose level and lipid-peroxidation with amelioration of hormonal disturbance and enhancement of testicular antioxidant status with relative to allox...

Fujun Miao1, Chunlan Shan2, Wei Yang3, Hao Wang3, Shuxiang Geng1 and Delu Ning1*

...xide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the liver of ALD. Walnut oil exerted the anti-inflammatory effects in the liver of ALD by decreasing the liver index, malondialdehyde (MDA) contents, and the expression levels of F4/80. The expression levels of key factors in the toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) signaling pathway reduced significantly after feeding with walnut oil to the ALD mice. Walnut oil may exert ...

Hong Yin*, Dan Yang, Ji-Jie Liu, Jing-Wei Ding and Dan-Dan Cui

...eroxide dismutase (SOD), glutathione peroxidase (GPx) activities and malondialdehyde (MDA) level were significantly increased in liver tissues with β-CM-7 treated. β-CM-7 decreased the fatty acid synthase (FAS) level significantly. The results suggest that β-CM-7 can change the dyslipidemia which is induced by aging. The mechanisms of the regulating effects likely tend to pass through controlling the oxidative stress and balancing the level betw...

Kanakuntla Sandhyarani*, Dhoppalapudi Madhuri, Yadala Ravikumar 

...teins, serum albumin and glutathione stimulating hormone (GSH). Grossly, chalky white deposits of urate crystals on the serosal surface of pericardium, liver, intestines, air sacs, kidneys and ureters. Microscopically, tissue sections show urate crystal deposition in parenchyma of the organs along with infiltration of inflammatory cells. Incorporation of low protein diets, jaggery mixed water, supplementation of B complex and electrolytes helps in the control ...

Semra Okur Gumusova1, Gul Fatma Yarim2, Cuneyt Tamer1,*, Ayris Salt2 and Gokhan Inat3

...eroxide dismutase (SOD), glutathione peroxidase (GPx) activities and malondialdehyde (MDA) concentrations were measured by the spectrophotometric methods. Data obtained revealed higher MDA levels in IPNV infected cells than negative control medium (p<0.001). However, SOD and GPx levels in IPNV infected cells were lover than negative control cells medium (p<0.001). These results indicate that, cell damage in RTG-2 cell line, that is caused by IPNV is asso...

Qaisra Siddique1*, Sajid Abdullah1, Huma Naz2, Khalid Abbas1, Laiba Shafique1 and Qingyou Liu3

...chemical markers such as glutathione S-transferase (GST) activity and total protein contents in various tissues (gills, hepatic, renal, brain, muscle and cardiac) of Labeo rohita was determined. Fish was exposed for 60-day and sampling was done after 7-day. Results showed that the GST activity was considerably increased in L. rohita as compared to control. The GST activity was enhanced in various tissues (hepatic, brain, cardiac, gills, renal and muscle) of CP...

Asmaa Sh. Fayed1*, Safaa M. Abo El-Soud2 

...ntioxidant capacity, the glutathione, and nitric oxide contents of the coated meats were higher than those of the control meat. Four percent of GA/ zein wax film significantly reduced the abundance of E. coli O26 by 3 log10 CFU/g when compared by uncoated meat chunks. We conclude that incorporating GA into zein wax film can effectively improve the stability and shelf life of veal meat chunks during chilled storage.

Keywords | Gallic acid, Zein, E. coli...

Mohamed Abd El-Fattah Abo-Farw1, Maged Ahmed Aboul-Omran1, Abdel-Khalek El-Sayed Abdel-Khalek2* 

...ed (P<0.0001) reduced glutathione (5.66±0.182 vs. 4.71±0.302 mmol/l) and total antioxidant capacity (1.64±0.046 vs. 0.76±0.049 mmol/l), and increased (P<0.0001) in malondialdehyde (0.80±0.043 vs. 1.68±0.064 mmol/ml). Mastitis significantly decreased serum concentration of progesterone (P4), estrogen (E2), thyroxin (T4), zinc (Zn), and selenium (Se) by about 24.05, 13.80, 5.36, 2.50, and 3.44%, respectively, while...
Maha Khalil1, Gamal Shams2, Hosny Abdel Fadil2, Nagah Edrees2, Mostafa Abonorag1, Nasser El-Sabbagh3, Eman A. Ahmed4*
...ng the reduced levels of glutathione peroxidase, catalase, and superoxide dismutase were reported. Conclusively, the results of our experiment suggest that that GSPE is a good feed additive for alleviating the negative impacts induced by aflatoxin B1.
 
Keywords | Aflatoxin B1, Hepatotoxicity, Liver apoptosis, Proanthocyanidin, Quails
...

A. Samy1*, H.M.A. Hassan1, Fatma T.F. Abd-El Ghany2, Shama H. Morsy2 

...dismutase, catalase, and glutathione peroxidase) compared with the control. Slightly (P>0.05) decreased in malondialdehyde of all treatments compared to the control. Also, there is no any negative effect on the thyroid hormones with any treatments compared to the control. These results suggested that rabbits fed diets enriched with curcumin or garlic extract could have better performance, carcass characteristics, and antioxidant status compared to the contr...

Uzma Jabeen1, Asmat Salim2*, Irfan Khan2, Nadia Naeem3 and Rubina Mushtaq4

...d and the mRNA levels of glutathione peroxidase-1(Gpx1), NAD(P)H quinone dehydrogenase 1 (Nqo1), 24-dehydrocholesterol reductase (Dhcr24), dual oxidase 2 (Duox2), and isocitrate dehydrogenase-1 (Idh1) were analyzed in the kidney tissues by RT-PCR. Extent of injury was analyzed by the change in expression of kidney injury biomarkers, kidney injury molecule-1 (KIM-1) and osteopontin (OPN), while the effect of DOX was also analyzed in terms of changes in the anti...

Ikele*, Chika Bright, Ujunwa Aghaji, Mgbenka, Benard Obialo 

...e, superoxide dismutase, glutathione peroxidase, and malondialdehyde activities in the gill were between day 14 and 21. Significant levels (p<0.05) of floc volumes (67.33 to 72 ml) were obtained from the total suspended solids maintained between 111 to 324 mg/L. Total heterotrophic bacteria present in the biofloc media were higher in CA 20:1 with a significantly peak value of 390X104 cfu/ml compared to other groups. The C:N at 10 and 20 utilizing cassava a...
Asmaa Khamis1, Osama Abdalla1, Mohamed Hashem2, Noha Abdelnaeim1*
...a significant decline in glutathione and superoxide dismutase in the CCl4 group. However, intoxicated groups treated with PN and PM showed marked improvement in the measured parameters. Therefore, PN and PM have antioxidant and anti-inflammatory effects, especially PM, which showed better improvement than PN against CCl4 hepatotoxicity in rats.
 
Keywords | Phyllanthus niruri, Plantago major, carbon tetrachloride, hepatotoxicity, h...

Rawda S. Mohamed1,2, Mohammed Y. Matoock2*, Abeer H. Abdelrazek2 

...londialdehyde (MDA), and glutathione (GSH) were measured. Mice were subjected to open field, plus maze, and dark light activity box tests. Swiss Multiple Acute concurrent Stress (SMAS) showed more responsiveness to MAS than Balb/c Multiple Acute concurrent Stress (BMAS) in most biochemical and behavioral parameters, with an elevated level of corticosterone and MDA IL-6, and TNF-α and reduced levels of GSH. In conclusion, SMAS showed a more effective resp...

Muhammad Hammad Fayyaz*, S. Murtaza Hassan Andrabi and Muhammad Shafiq Haider

Muhammad Akram1*, Muhammad Imtiaz Shafiq2, Amber Malik3, Farmanullah Khan4, Munir Ahmad Bhinder5 and Muhammad Sajjad6

...nisms include endogenous glutathione concentration, superoxide dismutase, catalase, and glutathione S-transferase (GST). GST neutralizes reactive oxygen species to regulate physical homeostasis in the body. The target of this study was to evaluate the molecular role of GST genotypic polymorphism involved in the development of CVD. For this case-control study, a total of 504 participants including 261 CVD patients and 243 hea...

Entesar Z. Eliraqy1*, Basant M. Shafik2, Yasser S. Hussein1, Abdelwahab A. Alsenosy3, Emad A. Abd allah1, Mohamed F. Saad1 

...ntrol group. Activity of glutathione peroxidase, activity of superoxide dismutase and alpha glucosidaseLysozyme elevated (P < 0.05) in G1, G2, G3 treated groups than control group. Different concentrations of garlic extract reduced the malondialdehyde than control. Finally, it can be concluded that garlic extract additive to extender would be useful to improve semen quality and antioxidant enzymes of buffalo-bulls spermatozoa after different processes (cool...

Al-Hassan M. Mostafa1*, Gehan Mohammed Sayed2 

... (PC), Catalase, reduced glutathione (GSH) and superoxide dismutase (SOD). Garlic and coriander treated goats showed significant reduction of FEC as compared with control positive ones. Treated goats exhibit no changes in total peroxides while there were non significant changes of PC, MDA, Catalase and SOD, in contrast there was an obvious increase of GSH. Histopathologically, Abomasum tissue restored completely normal histological features in Garlic treated g...

Saydat Saad Abd El-Megeed1, Walaa Yehia El-Sayed1*, Tarek Khamis2 

...improved catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD). A reduction was found in the gene expression in the hepatic homogenate of Patched 1, hedgehog-interacting protein (Hhip-1), smoothened (SMO), glioma-associated oncogene homolog 1 (GLI1), and extracellular signal-regulated kinases 1 (ERK1). On the other hand, there was a significant upregulation in the mRNA expression of peroxisome proliferator-activated receptor (PPAR) &ndas...

Aslı Çilingir Yeltekin

...OD), catalase (CAT), and glutathione peroxidase (GSH-Px)) compared to the control (p< 0.05). Therefore, these data may reflect one of the molecular pathways that play a role in tebuconazole toxicity.

...

Noha M. Abd El-Azeem*, Hemat A. Abdel Magied, Mervat N. Ghazal, Nehad A. Ramadan, Enayat H. Abo El-Azayem, Y. S. Hussein, Heba H. Habib 

...ioxidant capacity (TAO), glutathione peroxidase (GPx) and superoxide dismutase (SOD), with significant improve in A/G ratio and decrease malondialdehyde (MDA) in the treated groups in compared to the control group. In conclusion, turmeric, MOS and Biostrong supplements had a beneficial effect as natural antioxidant additives, especially the mixture among them, by protecting against oxidative stress factors caused by pregnancy and lactation in female rabbits un...

Reda Hassan*, Bahaa Abou-shehema, Sherif Zayed, Micheal Gorgy, Shama Morsy, El-Sayed Abu El-Hassan, Mahmoud El-Gbaly, Hanaa Basuony, Ebtehal Hassan 

...) diminished the reduced glutathione (GSH), glutathione S- transferase (GST). In addition to, dissemination of aflatoxin residue in broilers liver was detected. Nevertheless, dietary addition of HSCAS and SC, in separate and combined forms, alleviated the above-mentioned alterations. The combination of HSCAS with SC was more efficient than having them in a separate form.

Keywords | Aflatoxin, Broiler, Adsorbent compo...

Ibrahim Samir Abd El-Hamid1, Alaa Emara Rabee2, Moustafa Mohamed M. A. Ghandour2, Rasha Salah Mohammed3, Ahmed Mohamed. Sallam4 

...antioxidant capacity and glutathione peroxidase levels were reduced (P≤0.05) in both treated groups. It can be noted that, supplementing of plant herbs mixtures had positive effects on some reproduction and immunological traits in goat males under heat stress conditions.

 

Keywords | Herbs additives, Quebracho tannins, Antioxidants, Sperm quality, Damascus goats. 

...

Lulu Ding, Ke Wang, Ruxue Huang, Wenjing Yu, Bingzhao Yan, Mengli Jiang and Jicang Wang*

... assessed. The levels of glutathione (GSH), malondialdehyde (MDA), catalase (CAT), and total superoxide dismutase (T-SOD) were measured. Histopathological sections of the kidney were made to observe the structural damage. Results showed that the red blood cell count (RBC), hemoglobinconcentration (HGB), and hematocrit(HCT) of serum were significantly reduced after Cd exposure for 4 weeks. Cd increased the expression of GSH and MDA and decreased the activities ...

Rukhsana Anwar1*, Ammara Abd-Us-Sattar1, Afifa Noor2, Kanwal Ashiq1,3 and Shah Jahan4 

...specific activity, total glutathione, superoxide dismutase, catalase, and malondialdehyde were determined in liver homogenates. The phytochemical analysis of extracts revealed the presence of many important bioactive compounds. Real-time PCR results showed that aqueous extract decreased the mRNA expression of CYP1A2, CYP3A4. The methanolic extract decreased mRNA expression of CYP2C9 and CYP3A4. Both extracts enhanced GST-specific activity, tGSH, SOD, and CAT a...

Owolabi Olutunmise Victoria1*, Saka Olusola Stephen2, Olashinde Oluwaseun Ruth1, Alli Smith Yemisi Rufina3

...oxidant enzymes, Reduced glutathione (GSH) activity, Superoxide dismutase (SOD) activity and Malondialdehyde (MDA) activity. When compared control and glibenclamide-treated rats, the antioxidant activity of the extract increases with advancing the dose of treatment. According to the findings, Cola acuminata young leaves have comparable anti-diabetic efficacy to that of a glibenclamide administration. This suggests a promising prospect in developing novel drugs...

Dalia Zaafar1*, Heba M.A Khalil2, Soha Hassanin3, Mohamed R. Mousa4, Mona G. Khalil1 

...ialdehyde (MDA), reduced glutathione, superoxide dismutase (SOD), tumor growth factors, and apoptotic TUNEL assay, were evaluated after three weeks in addition to Immunohistochemical analysis was done on the proliferating cell nuclear antigen (PCNA), hypoxia-inducible factor 1-alpha (HIF-1), PPAR, and cyclin D1. Results: Mice treated with Cis+Pio HD showed higher levels of SOD, GSH, p-ERK1/2 and p38-MAPK, as well as lower levels of MDA and tumor growth factor ...

Doaa H. Assar1, Rasha A. Al-Wakeel2, Zizy I. Elbialy3, Mahmoud M. El-Maghraby4, Helmy K. Zaghlool5, Adel A. El-Badawy4, Abdel-Khalek E. Abdel-Khalek6*

...erum and seminal plasma, glutathione, superoxide dismutase, catalase, and glutathione peroxidase significantly increased, while malondialdehyde significantly decreased in SPL groups. Based on our results, spirulina as a dietary feed additive (5 g/kg diet) could be used safely for improving growth, health, antioxidant defense system, and semen quality of growing cross-bred ram lambs from 10 to 15 months of age.
&n...

Abdulaziz A. Alaqil*

...n 70 (HSP70) density and glutathione peroxidase (GHS-px) activity, respectively. The general linear model procedure with one-way analysis of variance (GLM-ANOVA) was used to analyze the data. The results showed a significant (P<0.05) increase in the BT, H/L ratio, MDA, and CORT, and over-expression of HSP70 in the hens of LPS group. Also, significant (P<0.05) impairments were perceived in the feed consumption and conversion, and in the egg weight and pro...

Weijun Chen1*, Shiyang Gao1, Ping Sun1, Xiaohui Sun2, Yongbin Wei1, Jingyang Chen1 and Jialong Chen1

... and contents of reduced glutathione (GSH). Furthermoure, diet HF significantly decreased the mRNA expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1), and simultaneously increased the mRNA expression of tumor necrosis factor α (TNF-α), interleukin-1β (IL-1β), and IL-6 in liver of common carp compared to control diet (P<0.05). However, diet NaBT significantly improved fish liver health by decrea...

Hafiz Muhammad Arsalan1, Amina Arif1 and Muhammad Khalil Ahmad Khan2*

...e (SOD), catalase (CAT), glutathione (GSH), nitric oxide (NO), advanced oxidation protein product (AOPP), advanced glycation end products (AGE’s) and micronutrients (retinol, ascorbic acid, alpha tocopherol), complete blood count, liver profile, renal profile, lipid profile, serum electrolytes were evaluated in CML and control groups. Our study reported that no significant difference in biochemical profile among treated with Nilotinib or Imatinib tretate...

Chen Zhao, Lulu Ding, Ying Ye, Congying Kou, Haoran Xiao, Jing Zhu and Jicang Wang*

...increased the content of glutathione and malondialdehyde and decreased the content of catalase and total superoxide dismutase. Instead, Nar significantly attenuated these Cd-induced toxic activities. Furthermore, the protein expression levels of Beclin1 and P62 were increased in the Cd-treated group. Treatment with Nar can significantly inhibit the increase of P62 protein expression level caused by Cd, indicating that Nar has a certain inhibitory effect on cel...

Sherein H. Mohamed1, Soad El Naggar2*, Ayman A. Hassan3, Mohamed A.M. Mousa3, Mohamed M. Basyony3, Mohamed F. Sadek3, Mohamed A. A. Ahmed4, Saadia M. Hashem5 

...ide dismutase, catalase, glutathione peroxidase, immunoglobulins G and A.  Moreover, the extracts supplementation decreases ammonia-nitrogen, butyric acid, Escherichia coli, Clostridium spp., and Enterococcus spp., total cholesterol, high density lipoprotein, low-density lipoprotein, and triglyceride compared to the control group. Also, these extracts had positive effects (P<0.05) on the rabbit meat nutritional compounds, and decrease meat fat content,...

A.M. Abdul Azeem1, A.N. El shahat1* and Mohamed H.M. Abd el Megid2

... significant decrease in glutathione content and antioxidant enzyme activities), tumor necrotic factor-α (TNF-α) and apoptotic marker Caspase-3 compared to the control group. Rats received BPA along with SeNPs-CP showed significantly less severe damage and remarkable improvement in all the measured parameters when compared to BPA-rats. In this study it was concluded that the synthesis of selenium nanoparticles using a natural source such as grapefr...

A.M. Abdul Azeem1, A.N. El shahat1* and Mohamed H.M. Abd el Megid2

... significant decrease in glutathione content and antioxidant enzyme activities), tumor necrotic factor-α (TNF-α) and apoptotic marker Caspase-3 compared to the control group. Rats received BPA along with SeNPs-CP showed significantly less severe damage and remarkable improvement in all the measured parameters when compared to BPA-rats. In this study it was concluded that the synthesis of selenium nanoparticles using a natural source such as grapefr...

Xiaowei Huang, Yajie Wang, Jia Zhou, Junxiu Liu, Zhe Lin and Ruili Li*

...genase (LDH) and reduced glutathione peroxidase (GSH-Px) were detected by ELISA. The expression level of TLR4/NF-κB, and HandE staining was used to observe the renal tissue. In the results, compared with model group, the spleen index and whole blood viscosity was significantly decreased, while the thymus index, peripheral blood WBC, RBC, Hb, HCT, PLT levels, and NO, SOD, GSH-Px levels in serum were significantly increased. The levels of TNF-α, IL-6...

Azza M. El-Kattawy1, Tarek Abou Zed1, Randa Megahed1 and Mohammed El-Magd2*

...oxidant markers [reduced glutathione (GSH) and superoxide dismutase (SOD)]. These findings conclude that administration of Sim relieved pristane-induced arthritis, with best improvement in the Sim co-treated (prevention) group. Thus, Sim could be used as a protective drug against rheumatoid arthritis based on its immunomodulatory, anti-inflammatory, and antioxidant effects.

...

Mustafa M. Khalaf*, Rana A. Salih 

...hrombin time. Otherwise, glutathione (GSH), and total protein (TP) level was substantially reduced in the control group. Studies have demonstrated quercetin’s capacity to decrease cyclophosphamide’s effects on (MDA, ALT, ALP, TP, and AST) while increasing GSH. Also, quercetin significantly affects body weight for their group and mixed group with cyclophosphamide. The results demonstrated quercetin’s capacity to lessen the cyclophosphamid...
Mohamed I. El-Katcha1, Mosaad A. Soltan1, Seham M. El-Kassas2*, Mahmoud M. Arafa3, El-Sayed R. Kawarei 3, Karima M. El-Naggar1*
...ties while reduced serum glutathione peroxidase activity compared with CuO (P < 0.05). Moreover, serum lipid profile was significantly altered as triglycerides concentration was increased while total cholesterol was reduced in birds received organic and CuO-NPs. So, the organic or Nano forms of Cu could be used as safe alternative sources in layer diets replacing the inorganic Cu without compromising their productive performance.

...

Ying Chen1, Chao-Zheng Li2, Zhun Yu3, Jia Zhou4, Yan Xu4, Zhe Lin4, He Lin4* and Xiao-Wei Huang4*

..., malondialdehyde (MDA), glutathione peroxidase (GSH-Px) and catalase (CAT) in myocardial tissue were detected by ELISA. Hematoxylin and eosin (HandE) staining was used to detect the histological changes of rat myocardium. Western blotting (WB) was used to detect the protein expression levels of nuclear factor erythroid 2-related factor 2 (Nrf2), heme oxygenase-1 (HO-1), and NADH quinone oxidoreductase 1 (NQO1) in rat myocardial tissue. In the results, ECG sho...

Wei Wan1, Xiao-Li Wang1, Shu-Juan Wang2, Qin Si2 and Li-Qing Duan1*

...holinesterase (AChE) and glutathione S-transferase (GST) activities in P. sinica were assessed in vitro. Correlation between numbers of synergistic or antagonistic binary mixtures and AChE or GST activities was analyzed. The results showed that 2-ethylimidazole had the strongest acute toxicity against P. sinica adult, with a median lethal concentration (LC50) value of 0.52 g/L. Among the 66 binary mixtures, 19 showed strong synergistic effects, while 21 showed...

Tariq I. Almundarij

...; 8 for both breeds, the glutathione (GSH) and superoxide dismutase (SOD) values were lower in the overweight camels than in the healthy ones, with a statistically significant difference (P<0.05). Therefore, based on these results, reproductive abnormality in camels was associated with high BCS and abnormal blood metabolites. Knowledge of the camel’s metabolic status and BCS may offer a more solid foundation for preventing metabolic problems and incre...
Raza Ali Mangi1,2, Ali Raza Jahejo1,2, Afrasyab Khan1,2, Meng-li Qiao1,2, Muhammad Farhan Qadir1,2, Mazhar Hussain Mangi3,  Shi-xiong Yang1,2, Xin-yu Han1,2, Sheng Niu1,2, Ding Zhang1,2, Ying Wang1,2 and Wen-xia Tian1,2*
...he effect of recombinant glutathione-S-transferase A3 (rGSTA3) protein on HDR and PRRs in the thiram-induced TD chicken. One hundred twenty arbor acres (AA+) broiler chickens of seven-day-old were equally divided into six groups. Group A, B, and C were treated with 0, 20, 50 μg.kg-1 of rGSTA3 protein, respectively. Group D, E and F were treated with 0, 20, 50 μg.kg-1 of rGSTA3 protein + thiram 100 μg.kg-1. The results showed that chicks treated with t...

Tayfun Karatas1*, Betul Apaydın Yıldırım2 and Serkan Yıldırım3

...talase (CAT) activities, glutathione (GSH), total immunoglobulin (T. Ig), and white blood cell (WBC) levels. Moreover, CMN exposure led to degeneration, steatosis, and necrosis in liver hepatocytes as well as hyperemia and inflammation in the liver and caused degeneration, desquamation, necrosis and adhesion in the gill epithelium. Additionally, expression levels of 8-hydroxy-2-deoxyguanosine (8-OHdG) and Caspase 3 were severe in the liver and gill tissues. Ho...

HAFIZ MUHAMMAD ARSALAN1,2*, SUMMARA TABASSUM1, MUHAMMAD SHERAZ YASIN3, FAROOQ SALEEM4, ZEEMAL SEEMAB AMIN1, MUNIB ASHFAQ1, UMAR FAROOQ GOHAR5 & RASHIDA BASHIR6

Biologia (Lahore)

December

Vol.65, Iss. 2

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