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Aradhana Chopra1, Ravi Shukla2 and Tarun Kumar Sharma2,3*

...marker discovery, drug delivery, bio-imaging and molecular therapy. In this review we have summarized recent advancements and applications of aptamers in biology.

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Muhammad Mushtaq

E-mail | mushtaq@uaar.edu.pk

...h; maize grain bait in delivering the lethal amount of strychnine alkaloid in controlling the Indian crested porcupine, Hystrix indica, during 2006-07. Indian crested porcupine is a severe forest and agricultural pest throughout southern Asia and the Middle East, including Pakistan. The results suggested that in case of pre-baiting trial, a 25% reduction in burrow activity was achieved in case of groundnut – maize (1:1) grain bait loaded with 2% strychni...

Nayle Maria Oliveira da Silva1*, Ricardo do Carmo Zanella2

 

...rld. HCV induces chronic liver disease, which is characterized by a persistent hepatic parenchyma inflammatory process that may progress to cirrhosis and hepatocarcinoma. Viral clearance occurs in a minority of patients with viral hepatitis C, whereas chronic infection is established in 60 to 80% of all cases, 20 to 40% of which may evolve to cirrhosis and hepatocarcinoma. Genetic differences among infected hosts can determine the progression and outcome of th...

Kemi Funmilayo Omotesho1*, Isreal Ogunlade1, Opeyemi Eyitayo Ayinde2

...ural extension service delivery emphasize the need for accountability of extension to the end users. This study analysed farmers’ perception of the accountability of agricultural extension services rendered in Oyo State, Nigeria. Structured interview schedule was used in eliciting information from 195 farmers in rural communities across the four agro-ecological zones in the study area using a two-stage random sampling technique. Data used for the study w...

Oladipo Elijah Kolawole*, Oloke Julius Kola, Awoyelu Elukunbi Hilda, Olasunmibo Oluwatobi Gabriel, Ogunyale Tolulope Temitope

E-mail | koladipo2k3@ yahoo.co.uk

...duals usually leading to liver cirrhosis. Individuals living with Human Immunodeficiency Virus have a greater risk to the virus due to their impaired immunity. The study was carried out to determine the sero- prevalence of Hepatitis E among people living with Human Immunodeficiency Virus in Ogbomoso. The blood sample of consented two hundred and seventy five (275) subjects were obtained and their sera were screened for antibodies to HEV using Enzyme Linked Imm...

Moustafa Kardjadj1, Pam Dachung Luka2

...nes and the problem of delivery to maintain cold chain, there is need for a very strong regional coordination for effective and sustainable control of PPR in Africa. The African continent is currently divided into 57 countries (or independent territories), many of which rely heavily on livestock for fuel, motor power and sustenance with many also endemic to the disease. PPRV continues to decimate the small ruminant populations across much of the African countr...

 Zafar Khan, Asad Sultan, Rajwali Khan, Sarzamin Khan, Imranullah and Kamran Farid

 
...sent study revealed that liver contains significantly higher concentration of lead (Pb), Cadmium (Cd), Chromium (Cr), Iron (Fe), Manganese (Mn) and Zinc (Zn) as compared to thigh and breast muscle. The level of Pb in liver and Cd and Cr in liver, thigh and breast in district I , the level of Pb in liver and level of Cr in liver

Wan-Long Zhu* and Gao Wenrong 

...and COX activity both in liver and brown adipose tissue, suggesting that A. chevrieri was more sensitive to cold than that of photoperiod. Together, these data suggested that A. chevrieri mainly depend on increasing thermogenic capacity to cope with cold or winter condition.

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Laila M. Fadda1, Nouf M. Al-Rasheed1, Iman H. Hasan1, Hanaa M. Ali2,3*, Nawal M. Al-Rasheed1,4, Musaed Al-Fayez5, Aly M. Ahmed5, Nada Almutlaq1, Nehal Qasem1 and Reem Khalaf1

...ione (GSH) which lead to liver dysfunction and hence hepatotoxicity. N-acetylcysteine (NAC) is the best antidote for APAP but may induce a variety of side effects. This study was designed to compare the potential impact of NAC with that of Thymoquinone (THQ), and/or Curcumin (CUR) either alone or in combination on liver injury induced by inflammation, oxidative stress in response to APAP toxicity in rats. Serum aminotransfer...

Halide Nihal Açikgöz1*, Serdal Kenan Köse2 and Ali Açikgöz3

 

 

...s in Ankara. Eight small liver bait traps were used for catching flies. Chicken liver was used in the study to attract blowflies. Eggs and larvae of the flies that oviposited on the liver were raised and identified. Six different indices were used to determine diversity (Shannon-Wiener [H’], Simpson Dominance [Sd], Simpson Diversity [S], Margalef Species Richness Indices, Pielou&rsqu...

G.E. Odo1*, E.J. Agwu1, N.I. Ossai2, C.O. Ezea3, J. Madu1 and V. Eneje2

... The results on gill and liver tissues sampled showed concentration and time dependent significant increase (p < 0.005) in the values of malondialdehyde, catalase, superoxide dismutase, reduced glutathione, alkaline phosphatase (ALP), alanine aminotransferase (AST) and aspartate aminotransferase (AST). Similarly, aluminium phosphide enhanced levels of AST, ALT and ALP as both concentration and time dependent in elevation were recorded when compared to the c...
Muhammad Luqman Sohail1,*, Muhammad Sarwar Khan1, Muhammad Ijaz1, Muhammad Avais1, Muhammad Yasir Zahoor2, Omer Naseer1 and Muhammad Usman Saleem3
...which indicate renal and liver damage. Concentration of Na, K, Ca, Mg, P, Cu and zinc in serum were significantly decreased (P< 0.05), indicating tubular damage in kidneys. 
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Abdur Rahim1, Ghulam Abbas1,*, Sara Ferrando2, Lorenzo Gallus2 and Abdul Ghaffar3
.... The moister content of liver, muscle, viscera and whole body were not significantly different in control and treated ponds. These results concluded that feed including 42% protein and 20% lipid are best for culture of black-fin sea bream A. berda (body weight 8.5 to 235 g) in brackish water earthen ponds.
...
Jun Cui, Xiaoxu Zhou, Zhicheng Wang, Derong Kong, Xuemei Qiu, Hongdi Wang and Xiuli Wang*
... was mainly expressed in liver, with limited expression observed in intestine, skeletal muscle and kidney. CcWap65 was significantly up-regulated in the liver of crucian carp after heat stress, suggesting that increase in Wap65 gene may be related to high water temperature stress and play important roles in high water temperature environment of crucian carp.
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 Eman M. Farghaly1, Ahmed Samy1,2*, Heba Roshdy

...ed mainly from heart and liver. The recovered E.coli, S.aureus and P. haemolytica isolates recovered from mixed infection cases showed (57.1-100%) resistance to highly important antibiotic group (Doxycycline, Tetracycline, Trimethoprim sulfa methoxazole and Chloramphenicol) and showed dissimilar pattern of resistance to critical important antibiotic group. Salmonella isolates showed antibiotic resistance to Nalidixic acid (100%) and Nitrofurantoin (42.9%). Str...

Zahir Shah, Ahmed Nawaz Tunio, Shakoor Ahmad, Ijaz Ahmad, Javid Ali, Sher Bhader Khan

...ibiotics, analgesics and liver tonics during the first week post-surgery. Local antiseptic dressing was performed using povidone-iodine daily for one week and skin sutures were removed at 14 day post-operation.

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Mustafa Cengiz1*, Jama Hussein Ali2, H. Mehtap Kutlu2, Djanan Vejselova2 and Adnan Ayhanci3
...) on the toxicity of the liver induced by D-Galactosamine (D-GaIN) in rats. With this in mind, the rats were categorized into five groups. The study groups were given saline, 0.2 % dimethyl sulfoxide, D-GaIN, EA plus D-GaIN and D-GaIN plus EA, respectively. In the group given D-GaIN, the following transmission electron microscopic and light microscopic results were found: degenerative changes in the liver tissue, significant...

B. Ramanujam, R. D. Prasad, S. Sriram and R. Rangeswaran

Mass production, formulation, quality control and delivery of Trichoderma for plant disease management
... control, registration delivery, shelf-life, disease management.
 

 

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Sitansu Pan and Amrita Das

Population proliferation and spread of Trichoderma spp. in soil under two different delivery systems
...following two types of delivery systems, through organic based (vermicompost + neem cake (90% + 10% w/w)) and seed based (sterilized wheat seed) inocula. The population proliferation and spread of the antagonists were faster when they were applied through organic based inoculums over that of seed based inoculums from the point of application. Similarly population proliferation and spread of the antagonist was more rapid in sterilized soil followed by solarised...
Beenish Zahid1,*, Asim Aslam2, Zafar Iqbal Chaudhry2 and Raheela Akhtar2
... changes by damaging the liver and kidney tissues with histopathological effect on lymphoid organs of chicken.
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Hai-Ji Zhang1, Di Zhang2, Dong-Min Hou1 and Wan-Long Zhu1,*
... 7 days. RMR and mass of liver decreased significantly in fasting groups, which can return to the control level after refeeding. Fasting for 12 h decreased serum leptin levels, and leptin levels can not recover to the control level after refeeding. Interestingly, there were no post-fasting compensatory increases in food intake. All of the results indicated that A. chevrieri can adjust their physiological functions to cope with food shortage, mainly by d...
Baohua Chen1,2, Wenzhu Peng3, Jian Xu2, Jingyan Feng1,2, Chuanju Dong1,2 and Peng Xu2,3,*
...kidney, intestine, gill, liver, skin, blood and muscle of common carp. Expression profiles provided us more evidences to understand GST gene functions as well as their functional evolution post duplication. Overall, the whole set of GST genes provide essential genomic resources for future biochemical, toxicological and physiological studies in common carp.
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Ahmad Ali1,*, Sheikh Muhammad Azam2, Khalid Javed Iqbal1, Ghulam Mustafa1 and Mujahid Kaleem3
...ongenital abnormality of liver. Parent tigress (Rani) was also died in May, 2014 due to respiratory failure and cardiac arrest and female cub died in 2005 due to canabalism.
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Nasar Khan1,2, Fahad Ali3,7, Sulaiman Bahadar5,*, Khalil ur Rahman3, Abdul Aziz3, Noor ul Akbar4, Muhammad Daud6, Azam Hayat5 and Mujaddad ur Rehman5
...tocellular carcinoma and liver cirrhosis. A total of 659 HBsAg ELISA positive patients out of 16825 patients during July to October, 2013 were screened for HBV by real-time polymerase chain reaction. Out of 659, 522 (79.21%) were found positive for HBV, of which 318 (over all 4.4%) were male, while 341 (over all 3.55%) were female. The HBV PCR positivity rate was 80.18% (n=255) in males and 78.30% (n=267) in females patients. Among different age groups HBV PCR...
Jianping Gou, Jianli Xiong*, Baoxia Dong, Zhennan Liu and Manman Hou
...pared to males; however, liver and fat bodies did not differ between the sexes. The sex difference of these organs may contribute to different energy requirements for reproduction between males and females. Our findings suggest that female toads invest considerable resources into gamete production compared to males, and greater internal organs in females are a consequences of high energy requirements for reproduction, which favors females to produce more high-...
Hazrat Ali1,*, Wajid Ali1, Karim Ullah1, Fazle Akbar1, Sher Ahrar1, Irfan Ullah1, Irum Ahmad1, Ashfaq Ahmad1, Ikram Ilahi2 and Muhammad Anwar Sajad3 
...idneys > muscles > liver > gills > skin while for Zn the order was skin > kidneys > liver > gills > muscles.
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Ahmed Zein Elabdeen Mahmoud1, Muaz Magzob Abdellatif2* and Mohamed Abdelsalam Abdalla3

...is, hemorrhages in lung, liver, abomasum, small and large intestine. PPRV NP was detected in sheep (n=20) and goats (n=18), anti-PPRV NP was also detected among sheep and goats (n=162) by ELISA, 3ABC-FMD enzyme immunoassay were positive (n=6) when ovine sera were tested. The study revealed that PPR-FMD viruses were circulating in the region and warrants proper control measures. 
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Alaeldein M. Abudabos1,*, Abdullah H. Alyemni2, Elsayeid O. Swilam1 and Mu’ath Q. Al-Ghadi3
...l intestines and heavier liver as compared to unchallenged birds. Lesion score and oocysts secretion increased significantly in the challenged birds, however, Elancoban had no significant difference with the natural products. It was concluded from the present study that natural products could be effective in comparison with anticoccidial drug to control coccidiosis in broiler chicken. 
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Rabia Tahir1*, Khushi Muhammad1, Masood Rabbani1, Muti-u-Rehman Khan2, Farah Khan1, Hassan Bin Aslam1 and Arslan Mehboob

...route. For this purpose, liver and spleen samples (n=90) were collected from day-old-chicks derived from breeders at 14, 21 and 30 days of post-infection with AAV-4. The presence of AAV-4 DNA was detected through PCR. Chicks from virus-challenged breeders failed to show a clear and expected PCR positivity. The connotations derived from these findings are that vertical transmission via transovarian route is reported the field conditions. However, based on genet...

Zaheer Abbas*, Shaukat Ali, Jalal-Ud-Din and Ghulam M. Ali

...bacterium strains that deliver T-DNA into plant cell from which whole plant can be regenerated. The results indicated that optimal embryo physiological age is 15 and 18 days after pollination and transient transformation efficiency decreased at 22 days after pollination. Enhanced transient beta glucuronidase (GUS) expression with average frequency of 40.56% was noticed with three days of co-cultivation period while two days of co-cultivation period resulted 24...
Mehmet Guvenc1,*, Ayşe Nilay Guvenc3, Ökkeş Yılmaz2 and Mehmet Tuzcu2
...ct of resveratrol on the liver of rats induced by fructose was investigated. Adult male Winstarrats were randomly divided into four groups; control, resveratrol, fructose, and resveratrol plus fructose. Resveratrol was administered 30 mg/kg intraperitoneally. Fructose (10% w/v) was administered with drinking water for 56 days every alternate day. Fructose administration increased the hepatic omega-6/omega-3 and 16:1 n7 / 16:0 ratios (p<0.001, p<0.001), b...

 Zeenat Bano1,*, Sajid Abdullah1, Waqas Ahmad2, Muhammad Anjum Zia3 and Wardah Hassan1

... in vital organs (gills, liver and kidney) of fish, Cirrhina mrigala. The 3 different representative water samples and 60 fish samples (20 fish from each site) were collected from three sites i.e. fish-farm, hatchery and Indus River of Punjab, Pakistan. The results showed differences in physico-chemical parameters of water samples collected from all the sites. The concentrations of Zinc (Zn), copper (Cu) and nickel (Ni) were higher in river water...
Farid S. Ataya,1,2,* Dalia Fouad,3,4 Ajamaluddin Malik,1 Nikolaos E. Labrou,5 Mohamed S. Daoud1,6 and Hesham M. Saeed7
...amel testis, followed by liver, spleen, kidney and lung. CdGSTP1-1 was heterologously expressed in Eschericia coli BL21(DE3) as a ~24 kDa soluble protein and showed to be catalyticly active towards the model substrate 1-chloro-2,4-dinitrobenzene. The results of the present study provide new information into camelid evolution and give further insights into the diversity and complex enzymatic functions of GST superfamily.
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Amtul Jamil Sami1,*, Madeeha Khalid1, Rehman Shehzad1, Sana Mughal1 and A.R. Shakoori2 
...ral tissues like kidney, liver, muscle and lungs was also observed, as compared to control subjects. It was also recorded that the exogenous supply of bubaline PL reduces fat cells in the hypodermal layer of skin.
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Toshina Mushtaq, Muhammad Javed and Sidra Abbas*
...cantly increased both in liver and kidney after ZnCl2 treatments. Statistically significant increase in the liver and kidney peroxidase activity of 96-h LC50 exposed fish were found as 0.621±0.004UmL-1 and 0.219±0.002UmL-1, respectively as compared to the control fish liver (0.123±0.002UmL-1) and kidney (0.056&plus...
Jing Xin Mao1,2, Guo Wei Wang2, Yuan She Huang3, Rui Wang2, Guo Ze Wang4, Bing Zeng1 and Fu Yuan Zuo1,*
...were expressed in normal liver, heart, lung, kidney, spleen and small intestine. The results showed that: The expression level of BPI in lung of Rongchang pig was relatively higher level compared to that in heart, liver, kidney, spleen and small intestine. The expression level of BPI in liver of Landrace was relatively higher level compared to that in heart, lung, kidney, spleen and small ...
Serap Gelibolu1,*, Yasemen Yanar2, M. Ayce Genc3 and Ercument Genc4
...rgans, intestine and the liver. Taken together, it is plausible to state that a diet supplemented with MOS has positive effects on the survival rate and the fatty acids profile without any observable negative impact on body tissues and thus support the safe use of MOS in fish feed.
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Ghazala Saeed1, Rabia Wajid1* and Ayesha Yousaf Dar2
...section versus vaginal delivery among eclampsiapatients.It is a descriptive case series conducted in Department of Obstetrics and Gynecology, Lady Willingdon Hospital, from December 2014 to June 2015. In our study, 62.86 % (n=88) patients were between18-25 years of age and 37.14 % (n=52) were between 26-35 years of age. The mean+SD was calculated as 25.12+4.53 years. Frequency ofvaginal delivery in patients with eclampsia wa...
Rimsha Nawaz1, Muhammad Javed1, Sidra Abbas1* and Safina Kousar2
...s viz. kidney and liver were isolated and the peroxidase enzyme activity was analyzed. Activity of peroxidase was assessed by measuring the conversion of guaiacol to tetraguaiacol, spectrophotometrically, at a wavelength of 470 nm. The peroxidase activity was measured in the selected organs exposed to various sub-lethal concentrations of iron chloride. The results revealed that peroxidase activity was increased significantly in both kidney and
Tariq Mahmood1,*, Fakhra Fazal1, Faraz Akrim1, Hira Fatima1 and Muhammad Sajid Nadeem2
...rameters, among females, liver weight and heart length of the two species differed significantly (p < 0.05). Among males, significant differences were found between heart length (p < .001), weight of large intestine, stomach, liver and lungs, and weight of right and left testes (p < 0.05) of the two mongoose species. Other anatomical variables of the two species differed non-significantly (p > 0.05).
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Aneeza Jamshed1* and Syed Amir Gillani2 

... 91%), signs (effects on liver 92.9%), symptoms (88%), prevention in high prevalent areas (sterilized syringes and screened blood transfusion 86.5%) and management (88.7%). This study showed that it may be an important school health based intervention to educate students about the transmission, prevention and management of hepatitis C, which may help in declining the disease burden. Hepatitis C, Unsterilized syringes, Hepatitis C Awareness, Prevention of Hepat...

Attia Anwar1, Sajida Malik2*, Zobia Usman1 and Sadia Chiragh3 

...of berberine toxicity on liver enzymes, renal function, serum uric acid and blood cell counts of Sprague-Dawley rats. For this purpose, twenty Sprague-Dawley rats were divided in two groups. Group A (n=10) was given distilled water and Group B (n=10) was supplemented berberine hydrochloride with dose of 75 mg/kg body weight/day. 24 weeks post-treatment, blood samples were collected by cardiac puncture from both groups and tested for Hb (%), WBC, RBC and platel...

Noreen Rasul1*, Madeeha Rashid2, Aqeela Abbas1 and Rubina Sohail

...onths, total number of deliveries was 6459, out of them spontaneous vaginal deliveries were 52.2% (3372) and caesarean sections were 47.7% (3087). In 55.4%neonate’s(both preterm and term)early essential newborn care was practiced.Total preterm were 290 (4.5%), out of them 121 (2%) neonates were kept in Kangaroo Mother Care position and 129 (44%) were shifted to neonatal intensive care unit. 14% parents refused for KMC ...

Ayesha Saeed*, Mobina Naqvi and Ahsan Javed 

...ort was followed until delivery, and birth weight was recorded. Follow up could be completed for 50 women only and response rate was 49%. Descriptive statistics were calculated, and relative risk and multinomial logistic Regression were applied using SPSS version 22. Mean maternal age was 28.100+4.824 years, mean education was 12.400+2.138 years, mean BMI was 29.420+5.075 and mean household income was PKR 25641+16251.543. With these characteristics, the mean b...

Abida Sajid* and Aqsam Sajid 

...me in terms of preterm delivery, low birth weight and rate of caesarean section in young Primigravida. It was a cross sectional study, conducted in the department of Gynae & Obstetric unit 5 King Edward Medical University Lahore during a period of one year from May2013 April 2014. All primigravida young 15-24years with anemia enrolled for the study. Anemia is defined as hemoglobin<10.5g/dl (WHO Criteria), Iron deficiency Anemia is defined as serum ferri...
Nazish Shaukat1, Muhammad Javed1,Faiza Ambreen2* and Fariha Latif1
...enzyme) in the gills and liver of Labeo rohita. Experiment was conducted in the laboratory by exposing four groups of Labeo rohita to different doses of PbCl2 viz. 96-h, 2/3rd, 1/4th and 1/5th of LC50, separately, for 30 days and compared with control group. After 30 days, fish was sacrificed and their gills and liver isolated to determine the effect...

Sher Muhammad , Ijaz Ashraf*, Amir Khatam**, and Naima
Nawaz*** 

SOCIO-ECONOMIC CHARACTERISTICS OF FARMERS AND THEIR PARTICIPATION IN ACTIVITIES OF MODEL FARM SERVICES CENTERS IN KHYBER PAKHTUNKHWA, PAKISTAN
...utting emphasis on the delivery of demand-based services through their active involvement. This improved situation regarding availability of agricultural inputs and good decision making may result in active participation by farmers in farm related activities. The present paper focuses on farmers' participation in various activities of MFSCs as influenced by their socio-economic characteristics. The target population of current study consisted of the member far...
Asmatullah1, Chaman Ara1,*, Shagufta Andleeb2, Maha Tahir1, Beenish Zahid1 and Madeeha Arshad1
...dium and necrosis of the liver. Skeleton analysis of cadmium treated groups showed mostly un-ossified skeletons. The control mice showed normal ossification as compared to experimental groups. Morphological, histological and skeletal studies of fetuses treated cadmium chloride along with guava fruit extract revealed ameliorative effects on various kinds of birth defects. It is concluded based on this current study that guava fruit extract exerted a therapeutic...
Zhiping Hu, Hussain Ahmad, Jingfei Zhang, Lili Zhang and Tian Wang*
...londialdehyde content of liver in T1 group was lower than that of CON group. These results suggested that dietary supplementation of 10 mg/kg natamycin had a positive influence in broilers.
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Saba Parveen Samo1, Moolchand Malhi1,*, Javed Gadahi2, Yan Lei3, Allah Bux Kaciwal1 and Saeed Ahmed Soomro1
...red to A. The weights of liver, heart, kidney and spleen were not significantly different (P > 0.05) between the groups, however, the lung weight increased in B (1.15 ± 0.04 vs 0.99 ± 0.04, P < 0.05) compared to A. Digestibility trails revealed that utilization of dry matter (DM), crude protein (CP) and crude fiber (CF) increased (P < 0.05) by 13.71, 12.02 and 4.78% at week 3 and by 11.11, 11.8 and 3.46 % at week 6 in B compared to A. Am...
Wei Dang1, Ning Xu1, Wen Zhang1, Jing Gao2, Handong Fan1 and Hongliang Lu 1,*
...igher in the muscles. In liver, Hsp70 expression significantly increased after 38°C heat shock. We then collected other three lizard species, Plestiodon chinensis, Sphenomorphus indicus, and Scincella modesta, from geographical locations near each other, but with different microhabitats. We observed considerable variation in Hsp70 expression; the constitutive Hsp70 expression varied between org...
Muhammad Zahid Latif1*, Rahila Nizami2, Intzar Hussain3
Shagufta Andleeb*1, Shabana Shaukat1, Chaman Ara2
...oes, non-alcoholic fatty liver and pyknosis. Fresh garlic juice has successfully attenuated these toxicities and increased the body weight, crown rump length. Results of present study determine that garlic is a potential antidote to ameliorate the cadmium induced teratogenic and hepatotoxic defects in developing Gallus domesticus.
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Jun-Ying Liu, He-He Liu*, Jie Kou, Yang-Mei Zhao, Ji-Wen Wang, Liang Li and Xiao-Hui Du
...scription levels in duck liver, spleen and bursa of Fabricius were examined after a model for immune stress was implemented through LPS injection in Peking ducks. The results from this assay suggested that LPS injection significantly increased the concentration of tumor necrosis factor-α (TNF-α) in bursa of Fabricius (P<0.05), along with an increase in the concentrations of immunoglobulin-G (IgG) and interleukin-12 (IL-12) in the serum of...

Safdar Ali1*, Obaidullah Shafique1, Tariq Mahmood2, Muhammad Amir Hanif1, Ijaz Ahmed3 and Bashir Ahmad Khan

...grochemicals and novel delivery mechanisms to enhance crop production and decrease in pesticide use. Nanotechnology also contributes in increasing the crop yield in agriculture. One of the major contribution of nanotechnology in the field of agriculture is the formulation of nano based pesticides and fertilizers for increased crop production. Precise farming techniques can promote crop production without damaging soil and water, reducing losses due to leaching...
Huma Naz1,*, Sajid Abdullah2, Sidra Naz3, Sidra Abbas2, Wardah Hassan2, Shakeela Perveen2, Moazama Batool1, Laiba Shafique2
...and catalase activity in liver, kidney, gills, brain and muscle of the fish were also studied. The mean 96 h LC50 and lethal value for C. mrigala was determined as 47.56±0.04 and 93.89±0.07 mgL-1, respectively. The selected concentration of Fe+Ni+Pb+Zn concentrations showed strong and direct relationship with, fin movement followed by mucous secretion, hyperactivity and swimming rate for C. mrigala with R2...
Fazul Nabi1,2, Hui Zhang1, Muhammad Kashif Iqbal1 , Mujeeb ur Rehman1, Muhammad Shahzad3, Khalid Mehmood1,3 and Jiakui Li1,* 
...) on growth plate width, liver oxidative stress and toxicity in avian TD. One hundred and fifty broiler chicks were equally distributed into three groups: Control, Thiram (50 mg/kg/d) and SM (10 mg/kg/d) treated. Results showed that thiram caused lameness, decrease in alkaline phosphatase (ALP) activity and increase in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities in the serum along with decrease in level of antioxidant enzymes...
Tayfun Karataş
..., endogenous reserves in liver and muscle tissues of rainbow trout (Oncorhynchus mykiss). Eight-days of fasting caused a significant decrease in glucose, total protein, triglyceride, cholesterol, high-density lipoprotein and low-density lipoprotein levels as well as protein and lipid reserves in liver and muscle tissue of fish (p<0.05). The fasting period had no significant effect on the hepatic thiobarbituric acid...
Zhuanxia Chen1, Ningping Tao1,*, Xiao Qin1 and Dayong Liu2
... the tastes of the meat, liver and soup through different preparatory procedures which were used in traditional. The taste of Takifugu obscurus under different conditions were analyzed by sensory evaluation and electronic tongue technique. The characteristic of the taste substances were tested, such as free amino acids, nucleotides, trimethylamine oxide and betaine. Results showed that umami was the most prominent flavor. Compared with
Mumtaz Akhtar, Iffat Naheed, Khadija Waheed* and Amna Khanum
...ergoing normal vaginal delivery. The study was conducted at the Department of Obstetrics and Gynaecology, Teaching Hospital, Lahore from 02-09-2014 to 03-03-2015. Non-probability and purposive sampling techniques were used. A total of 220patients undergoing normal vaginal delivery at term after administration of per rectal misoprostol were enrolled with 95% confidence interval (C.I). The error margin was 5% and the prevalenc...
Muhammad Anwar Iqbal1, Habib Rehman2, Ali Hussain3,*, Faiza Jabeen4, Ijaz Ahmad2, Kamran Ashraf5, Muhammad Irshad Arshad6 and Omaima Khan7
...gher relative weights of liver (P = 0.57) and gizzard (P = 0.69). The relative caecal weights of all MOS-supplemented groups were greater (P = 0.10) compared with the group A. Serum concentrations of calcium, magnesium, copper and iron were not influenced by the MOS supplementations. Serum phosphorus level was higher (P < 0.05) in the group B compared with the group A. The caecal Clostridium spp. counts were more (P...
Imran Taj1,*, Ferhat Abbas1, Zafar Ahmad1, Mohammad Kamran Taj1, Deedar Ahmad2, Zahoor Ahmed2, Ghulam Mohammad2, Ajaz-ul-Haq1, Farooq Shahzad1 and Sabiha Azam3
...fore stomach, intestine, liver, kidney, pancreas and gall bladder of mice. 
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İnan Kaya1,*, Muhitdin Yılmaz2, Müge Mavioğlu Kaya3,Abdulsamed Kükürt4 and Mahmut Karapehlivan5
...pectively. The blood and liver samples were taken from the fish for biochemical studies at the end of the study period. Oxidative stress index (OSI) in plasma were evaluated as well as AST and ALT levels in the liver. Plasma OSI and liver AST levels in the groups with carbaryl and 2,4-D were compared with the control group, and they were found to be significantly higher. As a result, it wa...
Tahira Batool1*, Nabila Roohi1, Athar Mahmud
... of head, shanks, lungs, liver, gizzard, heart, and carcass yield comprising percent weight of breast and thigh. 
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 Tahir Abbas*1, Khawaja Raees Ahmad2, Asmatullah3, Khalid Pervaiz Lone4, Muhammad Ali Kanwal2, Sadia Suleman2

Reno-hepatic protective effects of Jambul against chromium induced anomalies in mice
.... On the 16th day blood, liver and kidney were collected for biochemical and histopathological analysis.Cr+6 treated group showed severe histological changes like necrosis, cirrhosis and dehydration in liver evident by significant elevation of Serum Glutamic Pyruvic Transaminase (SGPT), Serum Glutamic Oxaloacetic Transaminase (SGOT), Alkaline Phosphatase (ALP), total protein, bilirubin, globulin, creatine and uric acid along...

 Hamda Azmat1, Waqas Ali2, Arshad Javid2, Ali Hussain2, Syed Makhdoom Hussain3, Zara Saeed1,Syed Shafiq Hussain Bukhari4

Chromium contamination in water, sediment and its bioaccumulation in Indian major carps in River Chenab, Pakistan
...o;g/g) was recorded from liver whereas minimum 1.10±0.21 (µg/g) from muscles of the fish.

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Riffat Mehboob1*, Sami Ullah Mumtaz2, Zoya Manzoor3, Sajid Abaidullah2, Fridoon Jawad Ahmad1

Deranged biochemical and hematological profile of septicemia patients in Mayo hospital, Lahore
...e of serum biomarkers of liver, kidney and blood in the diagnosis of septicemia. 101 confirmed patients of septicemia from a tertiary care hospital in Lahore were included. Liver and renal function tests were performed for all patients. Patients were divided into 3 age groups on the basis of age: 30-50, 51-70 and 71-90 years. In Liver function Tests, ALT (37.62%), AST (50.49%) and ALP (99%...

 Mirfa Murtaza1, Sajid Abdullah1, Wardah Hassan1*, Khalid Abbas1, Huma Naz1, Muhammad Anjum Zia2

Studies on amylase and lipase activity in fishes fed with diet containing different feed ingredients

 Asma Karim1, Wajid Ali1*, Noreen Ahmad1, Muhammad Irfan2, Hafiz Abdullah Shakir3

Histological and biochemical study of liver of silver carp (Hypophthalmichthys molitrix) after acute exposure to pyrethoride (deltamethrin)
...al
alterations in liver of silver carp. The LC50 1.6 μg/L was determined. Fish (n=6) were dividing into 4 groups A (control)
B, C and D (experimental). Experimental groups B, C and D were exposed to 25%, 50% and 75% of LC50
respectively for acute exposure. The blood and liver tissue sampling was done after 96hrs for histology and
biochemical analysis [alanine amino transferase (ALT), and aspart...

 Muhammad Babar Khawar1, Muddasir Hassan Abbasi1, 2, Sana Fatima3, Khawaja Abdul Mujeeb2, Nadeem Sheikh1

Alterations in proteins and transaminases activity induced by thioacetamide in albino rats
...ely. Blood was obtained; livers were excised and processed for protein profile and transaminases activity
analysis. TAA injection resulted in significant alterations in serum proteins and transaminases levels. Significant
hypoproteinemia and hypoalbuminemia were observed in sera as well as liver tissue of both experimental groups
compared to control. Furthermore, transaminases activity was significantly ...

 Khurram Shahzad1*, Muhammad Naeem Khan1, Farhat Jabeen2, Nasreen Kosour3, Muhammad Sohail1, Muhammad Khalil Ahmad Khan1, Munir Ahmad1

Bioaccumulation of manufactured titanium dioxide
...nd
organs (gills, liver and muscles) were freeze dried. Freeze dried tissue samples
were digested with the help of nitric acid (HNO3) and perchloric acid (HClO4). Acid
digested samples were analyzed by Inductively Coupled Plasma Mass
Spectrophotometry (ICP-MS) foraccumulation of Ti, Cu and Zn nanoparticles in
various tissues (gills, liver and muscles). Ti and Cu accumulation in gills was
Hina Abrar1,2, S.N.H. Naqvi1,*, Muhammad Rashid Ahmed3, Asma Basharat Ali3 and Hina Yasin1,2
A.M. Abdul Azeem, A.N. El Shahat* and Ashraf M. Mounir
...n in serum activities of liver enzymes, level of hepatic and testicular lipid peroxidation and plasma levels of caspase 3 associated with significant increase in the levels of luteinizing hormone, follicle stimulating hormone and testosterone in addition to marked improvement in the level of total antioxidant capacity and glutathione content and the activity of superoxide dismutase activity and catalase activity of the liver...
Muhammad Muddassir Ali1,2 and İbrahim Hakkı Ciğerci1,*
...udy has been observed on liver cancerous cell line in term of its genotoxicty. So, genotoxic evaluation was carried out for the alcoholic and hexane extracts of T. turcica. Methanol extracts showed the highest DNA damage (20±1) at 200 µg/ml concentration and 11.67±2.52 at 50 µg/ml. Ethanol extracts showed the 2nd highest DNA damage (19±2)at 200 µg/ml concentration and 11 ±1at 50 µg/ml. While...
Shagufta Nighat1, Muhammad Sajid Nadeem1,*, Syed Israr Shah1, Amber Khalid1, Tariq Mahmood2, Ayesha Aihetasham3 and Muhammad Asif4
...more concentrated in the liver and kidneys, Zn and Pb showed high mean values as compared to other metals but these values were below the lethal levels. Within the regions and sexes no significant variations were found in metal concentrations; however within three bat species metal concentrations varied significantly. This study provides baseline data for future comparisons and management of bats and metal concentrations in environment.
...
Gangchun Xu1,2, Fukuan Du2, Yuyu Wang2, Yan Li2, Zhijuan Nie2 and Pao Xu1,2,*
...pressed in the gills and liver while PTGES2b was strongly expressed in the gills and testis. Expression of both PTGES2a and PTGES2b decreased from stage III to stage V and PTGES2a was significantly more highly expressed than PTGES2b. In the spawning process, the expression of PTGES2a did not significantly change, remaining at a low level. In contrast, PTGES2b expression significantly increased during spawning. T...
Kalimullah Khan1,*, Hafsa Zaneb2, Zia Ur Rehman3, Hamza Maris4 and Habib ur Rehman1
...lative weights of heart, liver, kidneys, spleen, gizzard and intestines. Results showed that supplementation of phytase enzymes affected the weight and length of small intestine and feed conversion ratio (FCR) and did not affect the other zoo technical variables like body weight, feed consumption, and weight gain during the whole experimental period. Application of phytasefailed to exert any influence on the weights of gizzard, provetriculus, heart,
Tafail Akbar Mughal1, Muhammad Zubair Saleem2, Shaukat Ali3,*, Khawaja Khurshid Anwar1, Muhammad Majid Bashir1, Muhammad Babar4 and Muhammad Adeeb Khan1
...(CCl4) on the liver of Balb C mice and also to investigate the protective effect of Vitamin E pre-treatment on the carbon tetrachloride-induced hepatotoxicity. Study included the estimation of the activities of the enzymes such as ALAT (alanine aminotransferase), ASAT (aspartate aminotransferase) and LDH (lactate dehydrogenase) and biochemical components like glucose, urea, lipids, cholesterol and protein contents both in the <...
Fariha Latif* and Muhammad Javed
...e activity in the gills, liver, kidney, muscles and brain. Among the fish species, C. mrigala accumulated significantly higher concentration of all metals as compared to L. rohita and C. catla. Bioaccumulation of all metals among the organs followed the order: liver>gills>kidney>brain>muscles, however, metals followed the trend for their accumulation: Cd>Cr>Cu>Pb. Antioxidant (catala...
Hua-Lun Luo, Yi-Yu Zhang*, Yuan-Yu Qin and Lei Wu
...and glycolysis in animal liver. In this study, the relative quantitative real-time PCR analysis indicated that the duck ChREBP mRNA is widely expressed in all examined tissues. ChREBP mRNA level was the highest in abdominal fat and the lowest in gizzard. The g.247075G>A silent mutation in exon 10 was first identified by direct sequencing approach, and resulted in three genotypes of AA, GA and GG. Association analysis demonstrated that the

 Şaban Çelebi

...n on Se concentration in liver, heart, kidney and breast muscle. In addition, malondialdehyde (MDA) concentration and enzyme activities of glutathioneperoxidase (GSH-Px), superoxide dismutase (SOD) and catalase (CAT) in liver, heart, breast and thigh tissues of laying hens were determined in present study. A total of 96 White Lohman laying hens, aged 24 weeks, were randomly divided into 4 groups (n=24), each of which was com...
Huma Naz1,*, Sajid Abdullah2, Khalid Abbas2, Wardah Hassan3, Moazama Batool4, Shakeela Perveen5, Sadia Maalik4 and Sajida Mushtaq4
...ase in different organs (liver, gills, kidney, brain, heart and muscle) of fish, Labeo rohita. The LC50 of chlorpyrifos+endosulfan mixture was calculated as 1.95±0.02 μgL-1 for 96 h with the 95% confidence limits. The fish expose to the mixture (1:1) for 96-h. The results obtained from this study showed that superoxide dismutase, peroxidase and glutathione S-transferase activities in the liver
Shengjie Zhou1,2, Pengfei Wang1,2, Chao Zhao1,2, Mingjun Fu3, Jian G. Qin4, Lihua Qiu1, Zhenhua Ma1, 4,* and Maoshang Lin1
...n pompano.
...
Sher Bahadar Khan1,2,*, Zou Geng1, Cheng Yu-ting1, Asad Sultan3, Mumtaz Ali4,5, Irshad Ahmad6 and Rui Zhou1
...uses (20 each intestine, liver, meat and kidney), and 80 samples from super- and wet-markets (each 20 meat and liver) collected both in summer and winter. Isolates were tested for 15 antibiotics (CRO, AMX, GEN, STR, TET, CHL, CLR, LVX, OFX, GAT, CIP, SXT, AMP, LIN and AZM) according to the disc diffusion method and antibiotic resistant genes {tet(A), tet(B), tet(C), strA/strB, aadA, aac(3)IV), aadB, sul1, sul2 and sul3, blaC...
Syeda Ain-ul-Batool1, Sadia1, Kathrin Blasius2,3,4, Angela Kaindl2,3,4 and Ghazanfar Ali1,*
...ease, cardiovascular and liver disorders. So far 21 genes are reported that cause BBS (BBS1-BBS21). A consanguineous family having clinical symptoms of BBS9 is described in current study. Mutation was detected in BBS9 on chromosome 7p14.3 using whole exome sequencing (WES). A splice acceptor site mutation (c.1131G>A) in exon 3 was revealed by Sanger sequencing.
...
Iqra Jaffar, Zainab Sehzadi, Muhammad Adeel, Khalid P. Lone and Mehwish Faheem*
...uate oxidative stress in liver and gills by analyzing activity of glutathione-S-transferase (GST), catalase (CAT), glutathione (GSH) and by measuring lipid peroxidation (LPO). Catalase activity increased significantly in liver and gills of fish exposed to 10μg/l of DBP. Level of GSH and LPO increased significantly in gills while a non-significant decrease was recorded for GSH and GST in liver
Yan-Guo Han1,2, Jun-Hua Ye1, Qin-Tao Zhao1, Yong-Jie Huang2, Kai Li2, Yong-Fu Huang2 and Li Xu1,*
...i>CpG adjuvant and delivered by attenuated Salmonella choleraesuis at weeks 0, 3 and 6 of the study, and rats in control group (Group C) was orally given empty vector vaccine. Blood samples were collected before primary immunization and at weeks 3, 5 and 7 after primary immunization and body weight of offspring were weighed at weeks 0, 2 and 4 after birth. Both SS-14 and SS-28 DNA vaccines induced humoral immune response, howeve...
Uzma Jabeen1, Irfan Khan2, Nadia Naeem2, Asmat Salim2,* and Waseem Ahmed1
...tive stress in heart and liver tissues following DOX administration to rats. In this study, DOX was administered to rats intraperitoneally (i. p.) at 3 mg/kg at alternate days for two weeks. Heart and liver tissues were harvested and the mRNA levels of NAD(P)H quinone dehydrogenase 1 (Nqo1), glutathione peroxidase (Gpx1) and isocitrate dehydrogenase-1 (Idh1) were analyzed by RT-PCR. We observedvariable pattern of gene expres...

Shaikh Abdul Lateef, Zhou Lin, Wu Jian, Junjie Qian, Jonathan Hartanto Tan and Zheng Shusen*
 

...se progression manifests liver inflammation, chronic hepatitis and hepatocellular carcinoma. In this article, we present a comprehensive review characterizing the viral architecture, life cycle, infectivity mechanisms, immune escape strategies, disease epidemiology and preventive measures associated with HBV. The current antiviral therapeutics are not providing adequate protection against HBV. It is mandatory to characterize and devise novel antiviral therapie...
Nida Zia1, *, Ayesha Maqbool2, Muhammad Safdar3, Umm-I-Habiba1, Altaf Mehmood4, Muhammad Usman5, Zahid Iqbal6, Javed Iqbal6, Shahid Mehmood6, Amanullah Khan7 and Sajid Umar8
Nouf Alharbi*, Mai Elobeid and Promy Virk
...ium (Cd) accumulation in liver and hair, blood profile, catalase (CAT) and superoxide dismutase (SOD) activity in liver, malondialdehyde (MDA) levels in liver and serum, and histopathological evaluation of liver and kidney. Results showed that low dose of quercetin was significantly (p≤0.05) more effective than the high dose. Low dose was more efficac...

Sanaullah and Urooba Pervaiz* 

...ld was found after the delivery of improved farming practices through extension trainings. Tomato income was increased with a significant mean difference of Rs.104457 after extension recommendations. It is concluded that extension department performed well in the empowerment of farmers and increasing crop yield in the study area. The study recommends need based trainings for growers, availability of credit/loan facilities, provision of subsidized inputs and ir...
Tahir Iqbal1, Umer Rashid1*, Naveed Shahzad2, Amber Afroz1Muhammad Faheem Malik3 and Muhammad Idrees4

 

...kistan. The bile fluids, liver and spleen tissues were collected from overnight dead layer chickens (n = 8) from Pattoki region of Punjab province, Pakistan, during July to August 2016. The RT-PCR showed the amplifications of selected regions of helicase (186 bps, 2769-2954 nt) and capsid (280 bps, 5461-5741 nt) domain in the bile fluids of two birds. The histological data demonstrated pathological changes in liver and splee...
Maliha Ayub1, Muhammad Javed1, Fariha Latif 1*, Faiza Ambreen2, Komal Sabir1
...was measured in the fish liver, kidney, gills and brain and then compared with control group. The results showed that the antioxidant activity increased significantly in all organs of metal stressed fish as compared to the control fish. Among all test concentrations, the activity of antioxidant enzyme (peroxidase) was significantly higher in the fish liver under 96-hr LC50 manganese exposed fish as evident from it...
Aqsa Pervaiz1*, Rukhshanda Afridi1, Zahra Pervaiz1, Rabia Masood1 and Hira Pervaiz2
...hological changes in the liver of Nile tilapia, Oreochromis niloticus after acute exposure to methylmercury. The toxicity of methylmercury of Nile tilapia was studied in a static renewal bioassay for 48 hours and 96 hours (96 hours L.C-50 0.22 mg/L). The study was conducted on 40 fish that weredivided into 4 groups A, B, C and D. Group A was considered as control group.Group B, C and D were exposed to sublethal concentrations of methylmercury 0.044 mg/L...

Shaikh Abdul Lateef, Zhou Lin, Wu Jian, Junjie Qian and Zheng Shusen* 

...care and complication of liver transplantation in patients with pre-established hepatitis B infections. Information gained through this study would be helpful to have better management and life style in these deadly infections. 

...
Zhijun Zhong1, Rui Tu1, Xichun Wang2, Yi Geng1, Qicheng Xiao1, Yinan Tian1, Bin Wei1, Jiaming Dan1, Ya Wang1 and Guangneng Peng1,*
...tion and necrosis in the liver, lung, spleen, kidney, testicle, and lymph nodes, among which changes in the spleen were the most serious. Immunohistochemistry results demonstrated the detection of B. canis antigens in the lesions of all examined tissues. Strong positive staining was primarily found in the spleen, liver, and testicle. In conclusion, this study was the first to report the isolation of two B. canis
Qi Ren, Shufeng Sun, Chen Niu, Yuhong Li, Yingzhi Chong, Biao Li, Guoying Zheng and Fumin Feng*

 

...its expression may cause liver tissue damage. At present, few studies on CYP1A1 methylation and anti-tuberculosis drug-induced liver injury are available. Studying the relationship between CpG island methylation in the CYP1A1 promoter region and drug-induced liver injury is, therefore, of great importance. Anti-tuberculosis drugs induced hepatotoxicity in HL-7702 cells was investigated. De...
Muhammad Siddique1, Muhammad Shafique2,*,Abdul Mateen3, Naveed Shahzad4, Bilal Aslam2, Nasir Ahmad1 and Muhammad Usman Qamar2
Shou-Hong Zhang1*, Ying Zhang1, Kun-Ming Wen2, Wei Wu3 and Wen-Yan Li3
... feasibility of treating liver fibrosis with human Hepatocyte Growth Factor (HGF) carried by biotinylated ultrasound microbubbles plus biotinlated cationic nano-liposome composites (Bio-MB+Bio-CNLP) in bile duct-ligated (BDL) rats. In addition, we investigated the staging of hepatic fibrosis by using Perfusion-Weighted Imaging (PWI). We established a BDL rat model of hepatic fibrosis. HGF carrier was administered through tail-vein injections. The gene therapy ...
Sajida Sabahat1, Asif Nadeem1,*, Maryam Javed1, Muhammad Yasir Zahoor1, Abu Saeed Hashmi1, Ghulam Yasein2 and Ghulam Abbas1 
...nd specific tissues. The liver is the primary source of IGF-1 and considered as candidate genes for growth because they play a significant role in development and growth regulation. IGF-1 control protein metabolism and is extremely conserved region amongst species. IGF-1 have not been studied before in camel. The DNA samples of Marecha camel were collected from the Camel Breeding and Research Station at Rakhmani Bhakkar, Pakistan. Four polymorphic sites were d...

Nosheen1, Sajid Abdullah1, Huma Naz2* and Khalid Abbas1 

...activity in tissues viz. liver, gills, kidney, muscle, heart and brain of fish Catla catla exposed for 4-day. After each sampling (24-hr interval) fish were dissected and required organs were obtained. Results showed that the POD activity was augmented in all selected organs of Pb+2 exposed fish in relation to control. The POD activity in organs of fish followed the order: brain>liver>gills>kidney>heart>muscle...

Muhammad Naeem Khan* and Asad Jan 

...ld, influenza, head ach, liver and digestive problems and healing of wounds. The aim of the study was to explore phytochemical constituents of methanolic crude extract (MCE) and various solvent fractions and in-vitro antimicrobial activities of whole plant of D. botrys. Qualitative phytochemical screening of MCE and solvent fractions of D. botrys showed the presence of alkaloids, phenols, flavonoids, saponins, tannins and sterols, however in n-hexane fraction ...

Ankur Abrol, Madhumeet Singh, Akshay Sharma* and Pravesh Kumar 

...lead to deterioration of liver and kidney functions resulting in toxaemia followed by dam as well as fetal mortality. So, the most important aspect in successful management of uterine torsion lies in the correct and efficient diagnosis which can mainly be achieved by anamnesis, vaginal and rectal examination. However, prognosis of uterine torsion is mainly dependent on the degree and duration of condition and can be categorised into 3 successive stages i.e. st...
Rimsha Munir1, 2*

 

...cell line models (HepG2; liver cancer cell line and HCT-116; colorectal cancer cell line) were selected that showed inverse proliferation trends under 2D and 3D cell culture systems: HCT-116 displays decreased, while HepG2 displays increased proliferation rates under 3D system. The presented data indicated that the proliferative capacity of the given cell line was associated with its ability to deal with metabolic stress under 2D or 3D system. HCT-116 cells co...
Mehwish Faheem1*, Maleeha Rafeeq1, Aisha Majeed1 and Saba Khaliq2
...100, 1000 µg/l) on liver cyp1a1 and heat shock proteins mRNA level was evaluated using real time qPCR. Results revealed that exposure to bisphenol A caused decrease expression of cyp1a1 in a concentration dependent manner. Exposure to graded concentrations of bisphenol-A resulted in significant increase in mRNA expression of heat shock proteins (hsp70 and hsp90). In the light of present results, expression of cyp1a1 or ...
Chaman Ara1*, Asmatullah1, Sehrish Kanwa1, Asma Chaudhary2, Ayesha Siddiqua1
...a noticeable increase in liver, kidney and testis weights. Significant increase in levels of total alkaline aminotransferase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) and bilirubin was observed in blood plasma. Urea level showed a remarkable decrease, whereas creatinine level increased but not significantly. Histological examinations exhibited pyknosis, necrosis, vacuolations, increased sinusoidal spaces, karyomegaly, glomerulosclerosis, ...
Chaman Ara1*, Asmatullah1, Zainab Riaz1, Memoona1, Asma Chaudhary2, Shagufta Andleeb2
...bnormal vascular pole in liver and kidney respectively. But when turmeric powder was coadministered with BP, these damages were reversed to a great extent. So, this study has proved the protective role of turmeric against toxicity induced by BP in female albino mice.
 
Novelty Statement | Curcumin, an active component of turmeric along with its proven anti-fungal and antimicrobial activities also detoxify Paraben (suspected ...
Fariha Latif1*, Muhammad Javed2, Hammad Ahmad Khan2 and Khalil-Ur-Rehman3
... oxidative stress in the liver, kidney, gills, muscles and brain of Cirrhina mrigala. The 120-days old fish were exposed to 1/4th (11.81mgL-1) and 2/3rd (31.49mgL-1) of 96-h LC50 of water-borne Pb for three fortnights (42 days) in glass aquaria at pH 7.5, temperature 30°C and total hardness 250mgL-1. After each fortnight, fish were sampled from each treatment and different organs such...
Saman Muhsin Abdulkareem* and Nadir Mustafa Nanakali
...ces of oxidative stress, liver enzymes activity and the expression of cytochrome P450 1A1 (CYP1A1) against hepatotoxicity induced by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in male rat. Thirty adult male Wistar rats randomly divided into five equal groups. TCDD and QCT were orally administered at the dose of 10µg/kg /day and 20 mg/kg/day, respectively by gavage dissolved in corn oil for 90 days. At the end of the study, animals were sacrific...
Hazrat Ali1,2,*, Ezzat Khan1,* and Muhammad Jamal Nasir3
...ues such as skin, gills, liver and kidneys of two fish species i.e., Clupisoma naziri and Mastacembelus armatus. Cr concentrations in fish muscles ranged from 30.5±41.9 to 70.8±12.1 mg kg−1 wet weight, Ni from 16.7±10.2 to 103.5±114.1 mg kg−1 wet weight, Cd from 1.1±0.18 to 2.5±0.21 mg kg−1 wet weight and Pb from 29.7±18.3 to 97.7±95....
Kadry A. El-Bakry1, Lamiaa E.M. Deef1*, Lotfy Z. Habbak1 and Samia S. El-Naeli2
...biochemical analysis and liver tissues were collected and fixed in 10% formalin for histopathological studies. The present study showed that, PAT causes elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities and significantly increases serum level of malondialdehyde (MDA) but decrease the activity of superoxide dismutase (SOD) enzyme. On the other hand, in patuilin injected rats and treated with ginger, the activity of ALT, AST...

Bamigboye Olutoyin Omolara1, Fapohunda Funmilayo Omotoyosi1, Oladipo Elijah Kolawole1,2, Oni Mattthew Olujenyo1, Ajibade Oluwatosin Akinola1, Kaka Mary Oluwatosin1* 

...vival, increased risk of liver disease and hepatotoxicity despite undergoing antiretroviral therapy (ART). This study aims to determine the prevalence of serological markers of HBV based on serological markers among infected individuals with HIV. Ninety-three sera samples of HIV positive individuals were collected by Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital- HIV/AIDS Supporting and Counselling Unit, Ogbomoso. The collected samples w...
Ahsan Anjum1, Asim Aslam1, Raheela Akhtar1, Tahir Yaqub2,  Muti-ur-Rehman Khan1, Rizwana Sultan3, Saba Usman1Aneela Zameer Durrani4 and Muhammad Usman4*
...RNA. Furthermore, lungs, liver, kidney and lymph node were collected for histopathological examination. Of the 560 samples, 49 (8.25%) were found positive for CBPP. Maximum pathological lesions (50-75% of surface area) were seen in 34.69 percent lung samples, chronic type pleurisy in 97.96 percent, maximum aggregate pathological lesion score in 65.31%, while 48.98% lung samples had 6-10 numbers of sequestra. Besides, infiltration of inflammatory cells, congest...
Saara Ahmad1,*, Iftikhar Ahmed2, Saida Haider3, Zehra Batool4, Laraib Liaquat3, Fatima Ahmed5, Asra Khan1, Tahira Perveen3, Mirza Jawad ul Hasnain6, Saima Khaliq7 and Saad Bilal Ahmed8
...nsumption.
...
Gasem Mohammad Abu-Taweel
...ty, blood parameters and liver structure alterations. On the first day of pregnancy, 30 pregnant mice were equally divided into three groups. Tap water was provided to the control group (Group I). Group II and Group III animals were orally received 5 and 10 ppm of HgCl2.The treatment started the first day of pregnancy and continued to the day 15 after birth thearafter the dams were sitched to tap water. The behavioral results showed a significant in...
Elmas Ulutaş1,*, Abdullah Eryavuz2, Aziz Bülbül2, Abdur Rahman3,*, İsmail Küçükkurt4 and Cangir Uyarlar5
...ncreased (p<0.05) the liver Zn and Fe concentrations and mohair Fe levels but decreased the kidney Cu concentrations. It was concluded that the goats can tolerate the supplementation of high zinc in diet.
...
Irfan Shahzad Sheikh, Masroor Ahmad Bajwa, Nadeem Rashid, Muhammad Zahid Mustafa, Mohammad Masood Tariq*, Majed Rafeeq, Abdul Samad, Tauseef M Asmat and Asad Ullah
...) extracted from chicken liver were separately offered on days 1-21, 1-42 and 22-42 in experiments 1, 2 and 3, respectively. Under standard broiler management conditions, birds were divided into five treatment groups of 48 with four replicates. Commercial pre-starter feed, starter feed and finisher feed were offered on days 1-12, 13-25 and 26-42, respectively. Birds were vaccinated against Newcastle disease virus and infectious bursal disease. Relative lymphoi...
Fatima Hashim Abbas1,2* and Alaa Tareq Shakir Al-Hassnawi1
...ntrol group (23 normal delivery women (control positive), 10 normal unmarried women (control negative) were recruited in this study. Levels of lipid peroxidation (MDA level), catalase activity (CAT), total antioxidant capacity (TAC) and reactive oxygen species (ROS) were measured in the serum of all studied groups. MDA levels were significantly higher (p≤0.05) in aborted women with T. gondii compared to negative control. MDA levels were also signific...
Ahsan Numan1,4, Khadija Irfan Khawaja2, Abdul Basit Qureshi3Muhammad Shahbaz Yousaf4, Imtiaz Rabbani4, Hafsa Zaneb5 and Habib Rehman4*
...DSP. Occurrence of fatty liver was more (p<0.01) frequently seen in the patients with the DSP (87.80%) than having no clinical DSP (83.17%). Multiple logistic regression analysis showed that the DSP was significantly associated with age of the patients (OR:1.40, CI:1.24-1.67), duration of DMT2 (OR:1.24, CI: 1.01-1.35), HbA1c (OR:1.86, CI:1.61-2.05), blood fastening sugar level (OR:1.37, CI: 1.18-1.51) and triglyceride concentrations (OR:1.13, CI:...

Asmaa A. Darwish 

...total protein, globulin, liver enzymatic activities, kidney function tests, total lipids, triglycerides, MMP-2 and MMP-9 concentrations was depicted in the three diseased groups. On the contrary, the total cholesterol, HDL-cholesterol, LDL-cholesterol, minerals, electrolytes, trace elements and total antioxidants capacity concentrations significantly (P< 0.05) decreased in the three diseased groups. Both of MMP-2 and MMP-9 yielded a sensitivity and NPV as 1...
Gong Ga1,2 and SuoLang Sizhu2,*
...) and tissue ((including liver, spleen, kidney and intestine, n=21) by nested RT-PCR and qRT-PCR. HEV antigens were detected in tissues by immunohistochemistry analysis. Overall, we found that that eight serum samples (4.6%, 8/173) were positive to anti-HEV IgM antibody and Seventeen serum sample (9.8%, 17/173) were positive for anti-HEV IgG antibody. The HEV RNA positive rate was of 4.6% (8/173) in feces and serum. Moreover, the prevalence of HEV RNA was...
Qaisra Siddique1, Sajid Abdullah1, Huma Naz2*, Khalid Abbas1, Laiba Shafique3

 

...idney, heart, muscle and liver of Labeo rohita kept under sub-lethal dose (4.13 µgL-1) of chlorpyrifos. Fish was kept under chlorpyrifos stress for two months and samples were collected on weekly basis. It was noted that GST level varied significantly with duration. The GST level was raised in first 28 days after that it was dropped off up to 56-day. The trend of GST in fish tissues was observed as muscle<heart<brain<kidney<...
Renlong Lv1*, Ken-Ichi Horiguchi2, Shin-Ichi Tagawa3, Shoichi Ichihara4 and Norio Yoshida
...ake, blood biochemistry, liver function, and ruminal fermentation in sheep fed heat-treated jatropha meal. The experiment was performed twice (experiment I and II). The subjects were 6 wethers. They were divided into two treatments (rapeseed diet and jatropha diet) randomly and were tested by using a cross over method. Rapeseed meal and jatropha meal were relaced to the feed as a concentrate with proportion of 5% in experiment I and 10% in experiment II. The i...
Muhammad Shuaib Khan1, Shakeeb Ullah1, Nisha. A.R2, Muhammad Umar3, Muhammad Inamullah Malik1*, Syed Muhammad Kamal Shah1, A. Zaman1, Shakir Ullah1, Imdad Ullah1, Sumera Ali Khan4
... societies of Pakistan deliver many farm duties especially in the Punjab province, anterior Sindh, KP, Gilgat-Baltistan and Baluchistan. In the hilly areas men and women of the rural community use the donkeys for daily practice work like fetching water, collection of firewood for domestic use and sale in the nearby local market to cope their daily needs. The present study was carried out in three different rural towns of Dera Ismail khan district of KP in the ...
Yuhong Li1, Dongxue Wu1, Xue Wang1, Mi Zhang1, Hanyu Zhu1, Zhe Shi1 and Fumin Feng1,2*
...pment and progression of liver injury induced by anti-tuberculosis drugs in mice. A total of 168 Kunming mice were randomly divided into four experimental groups and one baseline group. The drug groups were orally administered with isoniazid (H), rifampicin (R), pyrazinamide (Z), and combination of these three drugs (HRZ) at 3, 5, 7, 10, and 15 days, respectively. Liver tissue pathologies and alanine aminotransferase (ALT) a...
Saira Saleemi1*, Zafar Iqbal1, Abdul Nasir Khalid2
...kin, gills, fins, heart, liver, kidney and intestine of fish and culturing it on four different culture media; Malt extract agar (MEA), Corn meal agar (CMA), Sabouraud dextrose agar (SDA) and Potato dextrose agar (PDA). The inoculated culture plates were incubated for 5-8 days at 28-32 oC. The fungal growth in the form of colonies of different shapes and colour appeared in agar plates. Four Aspergillus spp.; Aspergillus terreus (8.40%)...

 Abdus Salam* and Muhammad Zafarullah Khan

...t of overall extension delivery system, so agriculture extension department may establish a formal structure to initiate free SMS and voice message service in the easiest and understandable languages for increasing overall coverage of the extension delivery.

...

Razaullah1*, Iftikhar Hussain1 

A TWO-WAREHOUSE SUPPLY CHAIN NETWORK DESIGN AND OPTIMIZATION WITH CROSS-ROUTE COSTS AND BUDGET, MAXIMUM FLOW AND CAPACITY CONSTRAINTS
... of budget constraint, delivery mode, cross-route
costs, maximum flow by a shipping firm, production capacity of the plants, stocking capacity of owned and rented
warehouses and traffic factors on the supply routes in the mathematical model further broadened the problem. A case
study is solved to analyze how the model performs with the changing network characteristics. 

...

Aqeel Nawaz1, Muhammad Ali Kamran1 

PARAMETRIC SENSITIVITY ANALYSIS OF CONVEX STAR PORT PROPELLANT GRAIN FOR SOLID ROCKET MOTOR
...known as neutrality and sliver content. Sliver content results in tail-off of
the thrust-time curve. These two measures of merit are an important part of acceptable grain design. This paper is
restricted to the study of convex port star grain geometry and describes parametric evaluation to assess the effects
of seven independent and defining geometric variables of the star and other ballistic factors inc...

 Akhtar Nawaz*, Sahar Noor*, Iftikhar Hussain*, Afzal Khan*, Shahid Rashid**, Rehman Akhtar*

METHODOLOGY FOR POSITIONING MULTIPLE DECOUPLING POINTS IN HYBRID MANUFACTURING SUPPLY CHAIN SYSTEM
...ompetitive market. The delivery time is one of the most critical factors which influence management
of the supply chain networks and cost of the product. To respond to a given lead time, manufacturing firms need to
adjust their supply chain networks and design an effective interface for decoupling points in the supply chain based
on the cost to be incurred. In this paper, a modified cost model is proposed for a hybrid supply...

 Farid Ullah Khan·

PERFORMANCE ENHANCEMENT OF VIBRATION-BASED ELECTROMAGNETIC ENERGY HARVESTER DUE TO REDUCED AIR DAMPING
...voltage and load power delivered to a load resistance of 1000 increases from 46.3 to 79.4

Farid Ullah Khan*

MINIATURE VIBRATION SHAKER FOR MEMS-SCALE VIBRATION-BASED ENERGY HARVESTERS APPLICATION
...urrent drawn and power delivered are maximum, when the shaker is operated at the resonant frequency. Operating on the resonant frequency of 60 Hz, a maximum power of 0.6 W is delivered to the shaker at -48 dB gain level.
...

M A Khalid*, A R Ghumman**, H. N. Hashmi**, E. Tanveer*

INVESTIGATION OF PERFORMANCE AND SEDIMENT TRANSPORT OF LOWER BARI DOAB CANAL
...s been discussed using delivery performance ratio (DPR) a well known performance indicator. The sediment laden water flow problem may be described by three equations; the one dimensional equation of motion (momentum-equation) and the flow and sediment-continuity equations. All the three equations are partial differential equations and may be solved by the finite difference method. Numerical models can be used for this purpose. SETRIC model has been used in thi...
Zarish Yaqoob1, Saleema Bashir Shams2, Gaitee Joshua2 and Bibi Nazia Murtaza2,3*
...ills of fish followed by liver, kidneys, muscle and fat cells. Overall, seventeen fish species were recorded in the study areas indicating a decrease in the number of species in Ravi. The results have shown that the water of Ravi is unsafe for aquatic life and irrigation. Metal concentration in the fish meat is higher than the recommended dietary allowance (RDA) parameters indicating a serious health threat to both, the fish and human population.
...

 S.W. Shah*, M.I. Babar*, L. Khan**, M.N. Arbab*, H. Ullah*** and R.A. Syed***

RELIABLE MULTICAST IMPLEMENTATION IN JAVA
...a. The underlying delivery mechanism for multicast is presently based on User Datagram Protocol (UDP) that provides a “best effort” delivery service. Best effort implies that IP packets are treated with essentially equal weight, and while IP makes an effort to deliver all packets to their destination, packets may occasionally be delayed, lost, duplicated, or...

Parakriti Gupta1, Kapil Goyal2 and Mini Pritam Singh3*

Hepatitis E Virus and Zoonosis
...thy individuals to acute liver failure which leads to high mortality among pregnant women. Recently, chronic infections due HEV genotypes 3 and 4 have also been documented in immunosuppressed and transplant patients where prolonged virus shedding has been documented. The conventional diagnosis is established by detection of HEV antigen or anti-HEV IgM in acute sera. However, the detection of HEV RNA is important to establish the diagnosis in immunosuppressed p...
Magbolah Salem Helal Alzahrani
...the functional status of liver, in rats injected with carbon tetrachloride (CCl4), a known hepatotoxin. Thirty-six male albino rats were treated with subcutaneous injection of CCl4 in paraffin oil 50% V/V (2ml/kg b. wt.) twice a week for 2 weeks to induce chronic liver damage. After injection of CCl4, blood samples were obtained using the retro-orbital method to confirm ...
Mumtaz Ali Khan1, Sher Bahadar Khan2, Shakoor Ahmad2, Irshad Ahmad3, Kashif Prince1*, Ghazunfar Rashid1, Mahboob Ali1, Imdad Ullah Khan4Asad Ullah5, Naimat Ullah4, Muhammad Shoaib2 and Said Sajjad Ali Shah2
...m creatinine, bilirubin, liver enzymes, total, glucose and urea in blood significantly (P<0.05) increased. Fluctuations in mean erythrocyte counts (RBC), hemoglobin, PCV and total bilirubin were beyond the limits while others were within normal ranges in sheep infected with Clostridium perfringens type A. The total bilirubin, Liver enzymes, creatinine level, glucose and urea levels in blood were abnormal while othe...

Erum Bughio1, Ahmed Sultan Jatoi1*, Jibran Hussain2, Muhammad Hayat Jaspal3, Shahid Mehmood2, Hafiz Muhammad Ishaq4, Reema Bughio5 and Athar Mahmud2

Comparative Study of Carcass Traits in Four Strains of Japanese Quail (Coturnix japonica) at 3 to 6 Weeks of Age
...ed in mean slaughter and liver weight (g) in quail birds. Significant (p<0.05) differences were noted in keel length (cm) at week 3, 5 and 6 and keel angle at week-3. A significant (p<0.05) effect was observed in mean heart weight at week 3 and 6, gizzard weight at week 4, 5 and 6 and intestinal length (cm) at week 3, 5 and 6;  whereas, dressing percentage (%) and shank length (cm) differ non-significantly (p>0.05) in this study period. Imported ...
Gregory Ejikeme Odo1,*, Juliana Ekenma Agwu1, Nkechi Nweze2, Clara Ikegbunam2,Felicia Ekeh N1, Vincent Ejere1, Ngozi Ezenwaji1, Reginald Njokuocha2, Godwin Ngwu1 and Fabian Okafor1
...age of the enzyme in the liver due to hepatic injury in the treated rats. Previous biochemical studies have also confirmed the non toxicity of the plant extract of D. erecta to the kidney.
...
Yan Wen1, Liu Lian2, Zhuang Xun3, Murong Jiaying4, Cui Shuyi1, He Wanwen1, Mai Guanghuai5, Huang Wenzhu1, Chen Gang1,* and Wang Zhijun1,*
...ation therapy was also delivered to the patients in the treatment group in a specially designed garden setting under the guidance of therapists. The training included outdoor-assisted walking training, unassisted walking training, outdoor ladder training, and horizontal bar training. Ultimately, exercise capacity, lung function, symptoms, psychological state, and the Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise (BODE) comprehensive index of the ...
Shahid Ali*, Aijaz Ali Channa, Waqar Ahmad, Rafia Akram and Imbasat Yousaf
...s expelled out and dam delivered completely developed alive male calf with a gross anomaly (presence of a hole in the skull) which could not survive and died soon after the delivery. After the completion of obstetrical case using obstetrical mutation and forced extraction, dam developed the signs of peritonitis, subcutaneous edema and labored breathing.
...

Mohsin Ali Alias Mehran Khan Solangi1, Gulfam Ali Mughal1, Asad Ali Khaskheli1*, Turab Ali Korejo3, Nazeer Ahmed Rajput2, Qurban Ali Memon3 and Maqsood Ahmed Kumbhar4

Influence of Camellia sinensis on Broilers Performance
...eight of heart (13.53%), liver (61.1%), spleen (2.26%), proventiculus (58.13%), intestine (102.2%) and fat pad (81.41%) were found in D group (control) and minimum in C group. Mortality percent was equally higher in A group (2%), B (2%) and D (2%) compared to C (1%). Considerable (P < 0.05) variation was seen among A, B, C and D groups for feed and water intake. Prominent (P < 0.05) variation was also noticed for carcass weight of birds in D group compar...

Nadeem Abbas Shah1*, Ejaz Ashraf1, Hafiz Khurram Shurjeel2, Zaheer ud Din Mirani3, Usman Rafique1 and Raees Abbas Shah4

Assessing Perceptions of the Households-heads Regarding Food Security Status in Drought-hit Areas of District Tharparkar, Sindh, Pakistan: A Case Study for Agricultural Extension
...e of extension service delivery organizations in the area. District Tharparkar is the most vulnerable area in the country for food insecurity. Tharparkar has four tehsils such as Mithi, Diplo, Chachro and Nangerparkar. Out of four tehsils, one tehsil Mithi was selected purposively. A well- structured questionnaire and key informant interview guide were used for data collection. Collected data were analyzed by statistical package for social sciences (SPSS). Acc...
Muhammad Tahir Khan1, Shahid Mehmood2*, Athar Mahmud2Khalid Javed3 and Jibran Hussain2

 

... of breast, thigh, wing, liver, gizzard, heart, and abdominal fat for chicks fed compost at any level compared to chicks fed the control diet. Although, a slight reduction in breast and thigh weights was observed in chicks fed compost at 10% level compared to control chicks, but statistically this difference was not significant (P>0.05). Similarly, there were no differences (P>0.05) in serum biochemical indices, and immune-related parameters among the di...

Muhammad Javaid1*, Unsar Naeem-Ullah1, Waheed S. Khan2, Shafqat Saeed1, Mirza Abdul Qayyum1 and Muhammad Arslan Khan1

Role of Nanotechnology in Crop Protection and Production: A Review
...ield use of smart gene delivery system. This technology can also be useful for sustainable water use and irrigation water filtration. It also plays an important role in pollution reduction. Green revolution of any developing countries can be achieved by adopting nanotechnology.

...
Yasir Sharif1, Saba Irshad1*, Ammara Muazzam1, Muhammad Hamza Tariq1, Ambreen Kanwal1, Sana Rasheed1, Mabel Baxter Dalrymple2 and Anam Tariq1
...iron overload, disturbed liver and hematological profile and secondary complications in β thalassemia major (BTM) patients, the current study was carried on 408 subjects including 204 patients and 204 controls. For all 408 individuals; complete blood count (CBC), blood group, serum ferritin level and liver function tests were performed. Secondary complications were assessed by physical examination of pallor, splenomegal...

Turgay Şişman1,*, Muhammet Çağrı Keskin1, Hatice Dane1, Şeymanur Adil1, Fatime Geyikoğlu1, Suat Çolak2 and Esra Canpolat1

...l erythrocytes and lung, liver, and kidney histopathologies were evaluated in marsh frog (Pelophylax ridibundus) in agricultural areas. The most prominent histopathological alterations observed in lung tissue were noted as epithelial hyperplasia, thickness of alveolar septa, dilatations and congestions of blood capillaries, and melanomacrophage accumulation. An increase in the number and widening of melanomacrophage centers were also noted for

Syed Muhammad1*, Badar Naseem Siddiqui2, Farhat Ullah Khan1 and Nawab Khan3

Self-perceived Constraints of Extension Field Staff Affecting their Working Efficiency in Khyber Pakhtunkhwa, Pakistan
...le them to efficiently deliver their services.

...

Ahmed Weli Hussein Osman1,2, Rakibul Islam1, Md. Bazlar Rashid1, Abdiaziz Idiris Mohamud2,3* and Pravin Mishra4

Nanoparticle Tactics for the Oral Delivery of Insulin in Alloxan-Induced Hyperglycemia in Rat (Rattus norvegicus domestica) Model
...l carriers for insulin delivery. The current study was carried out to evaluate nanoparticle tactics for the oral delivery of insulin in the alloxan-induced hyperglycemia in rat model. Twenty male rats of age four months were randomly allocated into four different groups (T0, T1, T2, and T3). After acclimatization diabetes was induced in three groups of rats (T1; positive control, T2: insulin only insulin, and T3; insulin wit...
Q. Sun1, Q. Liu1, R. Di1, Y. Wang1, S. Gan2, S. Liu2, X. Wang1, W. Hu1, X. Cao1, Zh. Pan1, X. Guo1, Y. Yang3, H.E. Rushdi4* and M. Chu1*
...>THRSP expression in liver, subcutaneous adipose and tail fat tissues in Tan sheep (thin-tailed breed) were significantly (p<0.01) higher than that in Altay sheep (fat-tailed breed). The results obtained might expand our understanding of the important regulating role of THRSP gene in lipogenesis in fat-tailed sheep breed.
...
Li Yao1,2,3, AnQing Zhang1,2,3, HaiYan Zhang2, Jian Shao1,2,3, Ming Wen2,4, ChangAn Wang5, HaiBo Jiang1,2,3,* and Ming Li6,*
...i>Eucommia ulmoides Oliver (EUO) bark aqueous extract on growth performance and nutritional composition of rainbow trout (145.56 ± 4.12 g) (Oncorhynchus mykiss) fed five different diets, including 0 (EUO-0), 5 (EUO-5), 10(EUO-10), 20 (EUO-20) and 40(EUO-40) g kg-1 EUO bark aqueous extract. The muscle lipid of fish in EUO-40 was significantly higher than that in other groups (p < 0.05), and fish in EUO-0 showed significant...

Chibuzo Uzoma Izuogu1*, Robert Ugochukwu Onyeneke1, Loveday Chukwudi Njoku1, Gillian Chidozie Azuamairo1 and Mary Chikerenma Atasie2

 

Repositioning Nigeria’s Agricultural Extension System Towards Building Climate Change Resilience
... the extension service delivery in Nigeria should include adoption of new scenario thinking in communicating resilience building, establishment of emergency management unit by the agency, encouraging the involvement of the private sector in the extension service, transferring of research results on best affordable resilience practices to farmers as well as ensuring that government and other agencies are kept abreast with farmer’s feedback on their challe...
Jun Yan Bai*, Kun Peng Shi, Xiao Ning Lu, Xiao Hong Wu, Xue Yan Fu, Heng Cao, Hong Deng Fan, Meng Ke Chen and Yong Kang Ma
...ificant correlation with liver weight of meat quails(P<0.05), while locus B presented significant correlations with body weight, carcass weight, carcass net weight, liver weight, breast muscle weight and leg muscle weight(P<0.05). Loci A and B in the control region of MyoG 5’ can be used as the molecular marker of slaughter performance of meat quails during marker assisted selection.
...
Faheem Ahmed Khan1*, Sarzamin Khan2, Qurat-ul-Ain3, Saqib Ishaq1Muhammad Salman1, Abdul Rehman1, Ikram Ullah4, Kalsoom5 and Johar Jamil5
... not affect the level of liver enzymes. All the tested liver enzymes were observed to be present in the normal range in all the treated groups A, B, C and D. Feed conversion ratio was not affected in the treated groups and an average FCR of 1.6 was observed in all groups. From the present study it is concluded that indigenous S. cerevisiae can be isolated from different sources and can be used as a source of SCMP in b...
Naveed Akhtar1*, Muhammad Fiaz Khan1*, Sadia Tabassum1
Munawar Saleem Ahmad2 and Khan Dil Badshah3
...nd alterations in gills, liver, brain, kidney, intestine and muscles related with oxidative stress damage was observed. Genotoxicity increased with increase in time and concentration of cypermethrin. Cypermethrin is therefore extremly harmful to aquatic life.
...
Ying Liu1, Shankun Liu1, Hui Wang2 and Weihua Su2,*
...tioxidant enzymes in the liver and pancreas tissue at dose dependent manner. Our finding clearly supported the beneficial effect of caffeic acid on not only the diabetes mellitus, but also alleviating Gestational diabetes mellitus.
...
Yuanyuan Zhang1*, Liping Song1, Hui Guo2, Jun Wu1, Xiaoli Wang1 and Fangbin Yao1
...CCl4)-induced liver injury in common carp Cyprinus carpio. A 10-week feeding trial was carried out. A basal feed was supplemented with 0 (control), 30, 60, 120 and 240 mg/kg curcumin to formulate five experimental feeds. At the end of the feeding trial, the growth performance was determined. Subsequently, CCl4 was used for the model experiment. The plasma and liver were collected for the test aft...
Hazrat Ali1, 2* and Ezzat Khan1*
...us was: kidneys > liver skin > muscles > gills. Bioaccumulation factor (BAF) values of the metals in muscles of M. armatus were in the order: Cr > Pb > Ni > Cd. BAF values show that these metals are accumulated in the fish tissues and may pose a potential health risk to regular consumers. 
...

Joseph Anejo-Okopi1*, Jennifer Ifeoma Okpara1, James Mogoret Dabol1, Joshua Adetunji1, David Adeniyi2, David O. Amanyi3, Otobo I. Ujah4, Veronica David1, Patience Omaiye5 and Onyemocho Audu6

...development of end stage liver disease. Furthermore, larger studies are needed to gain better understanding of the HDV infection among chronic hepatitis B patients in endemic regions and other high-risk populations.

...
Canan Vejselova Sezer*
...dered as a useful drug delivery system for silymarin that has poor water-solubility and an excellent candidate for anticancer drug development.
...
Hesham Saeed1*, Manal Abdel-Fattah1, Ahmad Eldoksh1, Farid S. Ataya2 and Manal Shalaby3
...IFNα) of the camel liver, Camelus dromedarius was isolated and cloned using reverse transcription-PCR. Sequence analysis of that gene showed a 564-bp encoding a protein of 187 amino acids with a predicted molecular weight of 21 kDa. Basic local alignment search tool (BLAST) sequence analysis revealed that C. dromedarius IFNα gene shares high sequence identity with IFNα genes of other species, including C. ferus, Vicugn...
Chaman Ara1*, Asmatullah1, Saima Hanif1, Shagufta Andleeb2, Beenish Zahid3 and Madeeha Arshad4
...ine phosphatase (ALP) in liver and urea, and creatinine levels in kidneys, in Al exposed groups against control. In Al + antidote groups these deviations were less significant (P≤0.05). However, these morphometric and biochemical alterations improved to a great extent when onion extract was co-administered with Al. So it is concluded that Al caused morphological and biochemical disturbances in mice, whereas onion extract showed protective effects as well as...
Saqib Nawaz1, Sher Bahadar Khan1*, Umar Sadique1, Muhammad Israr2
Mumtaz Ali Khan3, Hameed Ullah Khan4, Muhammad Irshad5, Ihsan Ali1 and Haq Aman Ullah1
...27 (54%), dark congested liver 26 (52%), nephritis 23 (46%) and spleenitis 13 (26%). Microscopic lesions revealed a score of 10 of kidney tissue out of 15 while the lesion score of intestine revealed 08 out of lesion score of 15.
...

Syed Muhammad Aun Naqvi1, Sara Tahir1, Tanveer Ahmed2*, Huma Naz3, Amara Gilani4, Atif Liaqat5

...y, it was found that the liver contains maximum carbohydrates (percentage) relative to other sections of the body examined. Weight group W3 was found to have higher nutrients significantly (p<0.05) as compared to W1 and W2. Further, it is found that although the gills, liver, and gut of fish are not eaten directly by humans, but they have significant nutrient contents. The inferences of the present study would be helpful ...

Safia Bibi1, Saima Naz1*, Saba Saeed1, Ahmad Manan Mustafa Chatha2

...cal variations in gills, liver, kidney and skin of different fishes were noticed when exposed to heavy metals, thus indicating severity of heavy metal toxicity. The current study was focused on the toxicological effect of Cr, Hg, Ni and Cd in different type of fishes and it would be useful for the scientific community to restore different metals contaminating water. 
 
Novelty Statement | Histopath...
Shafaq Fatima1,*, Farkhanda Manzoor1, Humaira Amman1, Zakia Kanwal1, Asma Latif1, Zeeshan Ali2, Hamid Iqbal Gondal2, Sumera Sajjad1 and Raja Shahnawaz Janjua3
...-3 and n-6 PUFA in total liver lipids. However, the treatment group fed with diet B showed a significant increase in K (1.75 ± 0.14 %), FCR (0.97) and HSI (0.62 ± 0.1%) as compared to those in the control group. A high profile of DHA (C22:6) was observed in total liver lipids of fish in all three treatments groups (A: 0.31%, B: 0.41%, C: 0.40%) in comparison to the control group where DHA was not obs...

Mai A. Kilany1; Hanaa H.A. Gomaa1; Yousry E. Abo El-magd2 and Nermin Raafat2.

...d as HCV-related chronic liver disease progressed, espe-cially among patients with HCC.

...

Hanaa H. A. Gomaa1; Entsar A. A. Nassar2; K. A. El-Dougdoug3

...for treatment of various liver diseases. All the studied genetic parameters showed variations among milk thistle and parent varieties (plant height, main branch, total branches, head flower, fruit yield per plant). Concentration and yield amount of seven detected silymarin compounds using HPLC showed wide variations among varieties. They ranged from 9.2 to 34.78 mg/g fruits or 450.25 to 1250.25 mg/plant. The silymarin production has the same pattern of fruits ...
Abd El-Hamid, M.I1, Seham, A.El-Zeedy1, El-Sanousi, A.A2, Reda, I.M2, Nehal, S. Saleh1, Abbas, A.M1
... tissues either Lung and livers as well as Aborted placenta and nasal swaps from mares suffering from repeated Abortions, The current study used the gene synthesis technology introduced by Invitrogen to synthesis the glycoprotein D of the Kentucky Strain as reference strain to use it as appositive control for the envelope glycoprotein D of EHV-1 (EHV-1gD) cloned in pMA-T plasmid for optimizing the detection of the virus from field samples by PCR using 2 sets o...

Wesley D. Nafarnda, Japhet H. Baraya, Olatunde H. Olabode, Malang K. Simon

...demonstrated effective delivery and suitability of V4
thermostable ND vaccine use in scavenging village chickens in Adamawa State, Nigeria.
...

Moazama Batool1*, Sajid Abdullah2, Huma Naz3, Mubashar Hussain4, Sadia Maalik1, Sajida Mushtaq1, Tanveer Ahmed5 and Laiba Shafique6

...was studied as kidney>liver>gills>skin>fins>bones>muscle.
 
...

Md. Abdullah Al Mamun1,2*, Shamima Nasren1,3, Sanjay Singh Rathore1 and Kavalagiriyanahalli Srinivasiah Ramesh1

...ong the internal organs, liver lost its original reddish-brown and turned to yellowish-brown, intestinal duct remained empty and swelled. Severe infestation in catla caused eye opacity and tail rot indicated the devastating effects of A. japonicus. Infestation by this parasite resulted in histopathological changes in the skin and muscle, gill, liver, kidney, heart and different parts of gut tissues. According to the results ...

Aliya Munir1, Sajid Abdullah1*, Huma Naz2*, Khalid Abbas1, Tanveer Ahmed3 and Zahid Farooq2

...evel in kiney, gills and liver of fish Channa striata exposed to LC50 concentration (1.374µgL-1) of deltamethrin+endosulfan (DM+ES) mixture for 4-day. Sampling was performed after a 24-hr period. Fish were sacrificed and organs were collected to calculate the POx activity. It was observed that the exposure of DM+ES significantly accelerated the POx level in gills, liver and kidney of fish in a time dependent manner.&nb...

Ahmed Ali Moryani1, Nasir Rajput1*, Muhammad Naeem1, Atta Hussain Shah1 and Hidayatullah Soomro2

...lative weight of organs; liver, pancreas, spleen, heart, duodenum, jejunum, ileum, thymus and ceaca was observed significant (P < 0.05) in the herbs supplementary groups as compared to control group. The compound-II supplementary group F significantly (P < 0.05) increased the percentage of crude protein and fat contents as compared to control and other groups. Histomorphological examination of liver of broiler chicken ...

Dilan Ozmen Ozgun1, Gonca Alak2, Arzu Ucar2, Sinan Bilginer3, Halise Inci Gul3, Mahmut Kocaman2, Cem Yamalı3, Veysel Parlak2, Muhammed Atamanalp2, Ahmad Maslat4 and Telat Yanık2*

...dant enzymes of gill and liver, and changes in hematological parameters were determined in rainbow trout. For this purpose, rainbow trout alevins were exposed to 0, 0.25, 0.5, 1 and 2.5 mg/L of B4 and 1 ml of DMSO for 96 hours. Blood samples were collected for hematological analyzes and mortalities were recorded daily. Exposure to B4 caused significant changes in antioxidant enzymes of gill and liver of alevins (p<0,05). ...

Sajida Batool1, Saira Batool1, Sitara Shameem1, Fatima Khalid1, Tahira Batool2, Summera Yasmeen1, Saima Batool3*

...hological changes in the liver of albino laboratory mice, 20 adult male mice were equally distributed (n=10) into two groups. Atrazine was given at the dose of 200 mg/kg body weight through gavages for 28 days while the control (Cnt) group remains untreated. On the 29th day, all animals were sacrificed to recover liver for histological preparations. Atrazine (ATZ) caused various hepatic implications in the treated animals. A...
Sen Liu1,2, Yue Zhu2, Haixia Leng2, Ying Wang1, Xiangju Yin1 and Yajun Zhao1*
..., heart (H), kidney (K), liver (L), and muscle (M) tissues. An average of 67.0% CCGG loci was methylated in each tissue. There were significant methylation differences among tissues in full-methylation (p < 0.001) and total methylation (p = 0.001). Moreover, various unique methylated loci (15–59) were also detected. Non-negligible level of hemi-methylation (31.4%) existed, indicating that CHG methylation may also play a potential role in...
Mengke Wang1, Shucheng Huang2, Cai Zhang1*, Haizhou Gong1
Shunan Cuan1, Shuaishuai Wang1, Qi Shao1, Wenhao Xu1, Sudan Meng1
Pengfei Li1, Yuqin Wang1 and Zijun Yang1
...yrrhizinate in improving liver lipid metabolism and antioxidant capacity of laying hens is unclear. The current study examined the ameliorative effects of monoammonium-glycyrrhizinate (MAG) on liver lipid metabolism and antioxidant capacity in laying hens. One hundred eighty 320-day-old Hy-Line brown laying hens were allocated to five equal groups and administrated with the concentrations of 0 (control), 25, 50, 100, and 200...
Jun Yan Bai*, Zhi Hao Dong, Shu Juan Zhao, Ying Lei, You Bing Yang, Heng Cao and Kun Peng Shi
... Moreover, heart weight, liver weight, slaughter rate, whole net carcass rate, heart rate and breast muscle rate of french giant meat quail are slightly higher than those of savimalt meat quail (P>0.05). For savimalt meat quail, carcass weight shows extremely significantly postive correlations with carcass net weight, heart weight, liver weight, breast muscle weight (total), leg muscle weight (single), slaughter ra...
Rizwana Sultan1, Asim Aslam1, Muhammad Yasin Tipu1, Habib ur Rehman2, Saba Usman1, Ahsan Anjum1,*, Muhammad Saeed Imran1, Muhammad Usman3 and Muhammad Zahid Iqbal3
...e periportal area of the liver and mild depletion of lymphocyte in the bursa of Fabricius. The seven clades of avian Eimeria species strongly support that E. necatrix and E. tenella were closely associated and placed in the same sister clade with high bootstrap support (98%). Our two isolates RSI and RSII showed a homology index of 99.82% (nucleotide level) and 99.47% (amino acid level) with each other. The maximum similarity percen...

Saadu Mustapha1,2, Norsida Man1*,  Jasmin Arif Shah1, Nitty Hirawaty Kamarulzaman1 and Ahmadu Abubakar Tafida3

... the extension service delivery is the connection between agricultural research, extension and the farmers. The evolving new model of agricultural production and the small number of extension agents question old ways of providing valuable knowledge to farmers. The goal was to define the respondents’ socioeconomic characteristics, classify the types of ICT tools adopted by the respondents and identify factors influencing the adoption of ICT in extension s...

Yonis Abukar Mohamed1, Md. Nazrul Islam1, Md. Haydar Ali1, Mahfuza Akther1 and Abdiaziz Idiris Mohamud2*

...ascioliasis found in the liver were increase in the size of the organ were 14.6%. The infected bile ducts were also filled with blackish brown exudates giving the pipe stem appearance of the liver was noticed 13.3%. In histopathological study of acute Fascioliasis, there was lot of hepatocytic alterations like swelling of individual hepatocytes by increase in size and characterized by opaque cytoplasm. Sometime there was fat...
Ziyue Qin1, Zhen Wang1, Ali Mujtaba Shah3,4, Zifan Ning1, Yaofu Tian1, Qing Zhu1, Yan Wang1, Huadong Yin1, Zhichao Zhang1, Lu Zhang1, Lin Ye1, Diyan Li1, Gang Shu2 and Xiaoling Zhao1,*
...t muscle, leg muscle and liver (p < 0.05). Feed restriction also affected body weight gain, feed consumption, and leg muscle weight (p < 0.05). In faster- growing stock, chickens with full feed were heavier, but their leg muscles were lighter than 80% feed group, and there was a compensatory growth for the 80% feed group on d 49 and 70. The blood glucose on d 7 was higher in slower- growing group than the faster- growing group. Results also showed there ...
Luis Daniel Jiménez Martínez1, Vicente Morales Garcia2Carlos Alfonso Frias Quintana3, Alejandra del Carmen Castillo Collado1, Gloria Gertrudys Asencio Alcudia4, Carina Shianya Alvarez Villagomez4, Emyr Saul Peña Marín4,5, Bartolo Concha Frias1 and 
Carlos Alfonso Alvarez-Gonzalez4
...gill, stomach, brain and liver in adult males of A. tropicus from reared in captivity through three BestKeeper, geNorm and NormFinder algorithms. Based on our results we can conclude that in the three BestKeeper, NormFinder and geNorm algorithms, the most stable genes are ef1, followed by 18s rrna and actb where the gene stability will depend on specific tissue to analyze in tropical gar A. tropicus adults.
...
Rajesh Kumar Oad1, Nasir Rajput1, Imdad Hussain laghari1, Hidayatullah Soomro1, Muhammad Azhar Memon2, Abdul Sattar Baloch5, Qudratullah Kalwar3,  Mashhood Ahmed1, Zubair Ahmed Soomro2 and Waseem Ali Vistro4*
...eavier in group D, while liver and gizzard were heavier in group B than other groups, whereas, spleen and crop were heavier in group A, and gall bladder was heavier in group C. Mortality ratio increased in group A (p>0.05). Group E broiler spent more time on feeding (8.31 min/h). Group F spent more time on drinking (4.76 min/h). Group A spent more time on standing/walking (13.38 min/h). Group A spent more time on lying/sleeping (37.37 min/h) than other grou...

Muhammad Shahbaz1,2, Sajid Abdullah1*, Huma Naz3*, Khalid Abbas1, Tanveer Ahmed4, Sana Mehmood1, Muhammad Adeel Hussan5

...ssected and tissues viz. liver, muscle and gills were obtained to analyze the CAT activity. The CAT level was reduced in all treatments when compared control. CAT activity was observed higher in the gills, muscle and liver tissues of T1 diet fed C. idella as 14.68±0.90, 12.76±0.87 and 20.34±0.99 UmL-1, respectively. Comparison among diets for CAT activity showed the trend as T4<T3<T2<T1. The max...

Yaregal Tilahun1*, Benyam Tadesse1, Getachew Mekonnen2  and Tilahun Bekele3

... and training, on-time delivery of farm inputs, create market linkage, and improved tea nursery management were some of the suggestions made to alleviate the study areas’ tea production and marketing difficulties.

...
Hailong Dong1, Fubin Gan2, Khalid Mehmood3, Jiang-Yong Zeng4, Rao Zahid Abbas5, Mushtaq Ahmad Gondal6, Zhenyu Chang1 and Qingxia Wu1*
...tion were present on the liver surface. Our results provided a baseline data for the exposure of yaks to F. hepatica infection in the study area. Therefore, some important strategies and surveillance should be adopted to control F. hepatica on Tibetan Plateau, China.
...
Ho-Seong Cho1 and Yeonsu Oh2,*
...right middle lobe of the liver was severely affected by a tumor, and small tumor nodules were disseminated throughout the other lobes. The numerous tumor nodules were also found in the lung, stomach, kidney, heart and diaphragm, which were growing together, suspiciously metastatic, projecting, 5 to 40 mm in diameter and tawny to white in color. Histopathologically, the tumor was composed of prominent papillary-acinar structures and the cells had a resemblance ...

Ayesha Muzamil, Hafiz Muhammad Tahir, Shaukat Ali, Iram Liaqat, Aamir Ali, Muhammad Summer

...omach ulcers, dizziness, liver or kidney problems etc. Cytokines play an important role in the induction and suppression of inflammation. Cytokines are diverse form of proteins that act pro- and anti-inflammatory cytokines. The main component of immunity is IL-1. IL-6 cytokine play its role in regulation of metabolic reactions. The activity of various leukocytes is suppressed by IL-4 and IL-10 (anti-inflammatory cytokines) that triggers the production of pro-i...

Mohammed Naji Ahmed Odhah1,2*, Dhary Alewy Almashhadany6, Abdullah Garallah Otaifah7, Bashiru Garba5, Najeeb Mohammed Salah2, Faez Firdaus Abdullah Jesse4*, Mohd Azam Khan G.K3 

...45.06%), followed by the liver with 777 (35.19%), whilst in the imported breed, the fertility rates were 152 (6.88%), and 100 (4.52%) in the lung and liver respectively. This study, observed that Echinococcus granulosus parasite was present in both large and small ruminants within the study area and was responsible for high rate of organ condemnation. Hence, strategic endo-parasite eradication with a strong surveillance syst...

Eman H. Mahrous1, Mohamed. W. Abd Al -Azeem2, Faisal A. Wasel1, Waleed Younis2* 

...ablish this goal, lungs, liver, and heart (50 for each organ) were collected from 50 diseased rabbits (suffering from respiratory signs) from backyard rabbits at different localities in Sohag governorate, Egypt. All samples were submitted for PCR test and other conventional methods of identification. Recovery of P. multocida isolates of diseased rabbits from lung, liver, and heart were 23 (46%), 11 (22%), 13 (26%), respectiv...
Amr N. El-Shahat1, Refaat G. Hamza1,*, Ashraf M. Mounir1 and Madeha N. Al-Seeni2
...mical alterations in the liver and kidney of male albino rats.In the present study, gamma- irradiation (2 Gy every 3 days up to 8 Gy total doses) induced biochemical and oxidative damage in rats when compared to control group. In GFJ (10ml/Kg B Wt. /day) treated irradiated group, there were noticeable decreases recorded in lipid contents, concentration of serum urea, creatinine and uric acid, glucose level, activity of some liver
Abdullah Abdo Albegali1, Tayyaba Aftab1, Atiq-ur-Rehman1*, Amir Rashid1 and Mayada Mohammad1,2
...logical investigation of liver and heart was also done. The plant significantly (P < 0.05) and non-significantly (P > 0.05) decreased the levels of total cholesterol, triglycerides, high density lipoprotein, low density lipoprotein, very low density lipoprotein, asparate aminotransferase and alkaline aminotransferase. The plant maintains the level of HDL to a normal range. It is concluded from the study that the plant may be supportive treatment in comba...

Vladimir Safonov 

...nt of pathologies in the liver and excretory system . Therefore, food additives as an additional source of micronutrients may be recommended to maintain the antioxidant defense system capability in animals with low selenium levels in agrobiocenoses.

Keywords | Antioxidant protection, Biochemical composition, Cows, Pathology, Peroxidation, Selenium 

...

Muhammad1, Saadat Mehmood1,2, Atif Muhammad1*, Zaib Ullah3

...justify;">Abstract | The liver diseases like cirrhosis and hepatocellular carcinoma are mainly caused by the Hepatitis B and hepatitis C viruses. The present study is designed to assess the frequency and transmission of (HBV) and (HCV) among the local population of district Swabi. A preliminary study was conducted from 1st January to 31st May 2016. The study revealed that the ratio of Hepatitis B and C in the local population was found 103 (34 %) and 199 (66 %...

Noha M. El-Shabrawy1, Atef M. Kamel2, Aza S. Goda1, Gehad R. Donia1, Ahmed M. Salah-Eldein2* 

...se (Mn) in their muscle, liver, kidney and feather. Also, 16 water samples were collected to assess the level of heavy metals pollution in the study area. The result revealed that the kidney is the most tissue burdens the highest concentration of heaviest metals among the examined tissues. Egyptian barn swallow and house sparrow have a great tendency to accumulate heavy metals in their tissues among other examined birds. Levels of Pb in Egyptian barn swallow a...
Lin Ye, Jie-Lan Jiang*, Jia Xu, Rui-Ting Liu, Yin-Qiu Tian, Qing-Qing Zang, Jia-Yi Cao and Ming-Guang Mao*
...he intestine, kidney and liver, and up-regulated in gills under low-salinity stress in 3h to 6h, which indicates that TrCLCN5 may play an important role in the responses to acute low-salinity stress and would be useful in further understanding low-salinity adaption in T. rubripes.

...

Chunjie Song1, Shangquan Gan2 and Xiaoyun Shen1,3*

...d cell (WBC) in 3 drug delivery groups were extremely significantly lower (P<0.01) than the control group, and the contents of potassium (K), total protein (TP), albumin (ALB), globulin (GLB), and total antioxidant capacity (T-AOC) in the 3 drug delivery groups were extremely significantly higher (P<0.01) than that of control group, but there were no remarkable differences between the 3 drug de...

Muhammad Khubaib Hameed, Muhammad Aziz ur Rahman, Muhammad Ashraf, Safdar Hassan, Muhammad Riaz, Muhammad Qamar Bilal, Fawwad Ahmad, Muhammad Sharif*

...ve organs weight (heart, liver and gizzard) and immune organs such as bursa, spleen and thymus weight were also recorded. Weekly feed intake (3506g, 3531g) and body weight (2080g, 2139g) were better (P<0.05) in group fed arginine supplementation as 0.4 and 0.6%, respectively as compared to control group. Better feed conversion ratio (FCR, P<0.05) was shown by the all arginine treated groups with best FCR result in D group. Birds fed diet containing highe...

Xiaoli Cai1,2, Saeed Ahmed3, Zhixin Lei1,*, Jianping Wu1,* and Taolei Sun1,2,*

...DR). The present study delivers a possible elucidation to this problem via Nano Drug Delivery. Nanomaterials are relatively small as compared to ordinary antibiotics. The nanoparticle has unique physical and chemical properties, a large surface area, and an electric charge. Additionally, its antibacterial drug encapsulation can make it easier to enter the cell and improve the concentration in the target tissue. In the curren...

Syukriah Syukriah1, Ulinnuha Nur Faizah2, Hendry T.S. Saragih3*, Rizki Fitrawan Yuneldi4, Soenarwan Hery Poerwanto5, Raden Roro Upiek Ngesti Wibawaning Astuti5, Stephan Immenschuh6 

...;s and offspring’s liver and spleen were observed by using the TBARS Assay Kit, also the superoxide dismutase activities. As supporting data the histological analysis of the mother’s and offspring’s liver and spleen were prepared by using the paraffin method. There were sigificant results in the parasites levels and the increase in P. berghei infection followed an increase of oxidative stress in mothers and...

Juliet N. Ozioko1, Obinna V. Ayogu2, Benjamin O. Ezema1, Dilibe C. Uramah3 and Kingsley O. Omeje*,1

...tract of C. albidum. The liver marker enzymes aspartate transaminase and alanine transaminase showed no significant changes in their serum activity. Similarly, superoxide dismutase and catalase showed no significant increase after the period of study.

...

Fujun Miao1, Chunlan Shan2, Wei Yang3, Hao Wang3, Shuxiang Geng1 and Delu Ning1*

...from Juglans sigllata on livers of alcoholic liver disease (ALD) mice were studied. The results showed that serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the ethanol + walnut oil (ETH + WO) and ETH + silymarin positive group (PC) groups significantly decreased, and the lesions of ethanol-induced liver injury were relieved compared with the ethanol (ETH) group...

Alexander Tsybulsky1*, Tatyana Tabakaeva1, Anna Klimovich2, Michail Shchelkanov1, Eduard Kostetsky1, Maksim Aliev1, Anton Degtyarenko3 

...stics of the kidneys and liver, whose disorders are most critical in the progression of the leukaemic process; 3) Replicative and expressive activity of provirus FeLV in blood white cells (WBC); 4) Concentration of the IFNs and viral p27-FeLV-specific antigen in the blood plasma; 5) Expression of ifnα6, ifnα7, ifnβ1, ifnγ and ifnλ1 genes in WBC; 6) Expression of p53 and gadd45g genes in WBC. The concentration of the viral p27-FeLV...

Hung Van Mai1, Tuan Duc Nguyen2, Nang Thu Tran Thi3 and Hung Phuc Nguyen4*

...ding plasma lipid level, liver and muscle lipid contents, bile acid (BA) concentration, lipase activity, and lipid apparent digestibility coefficient (ADC) in pompano. The FSBM1 was produced by fermentation of defatted soybean meal (SBM) with Bacillus subtilis B3. The FSBM2 and FSBM3 were commercially available products, which were produced by fermentation of SBM with Lactobacillus spp. Five diets were formulated and denoted as FMD (fish meal-based diet), SBMD...

Sozan A.A. Ismaeil1*, Hassan Emam2 

...mical examination of the liver. Pigeons were collected from the squab breeder while Ibis were collected from streets at Shariq province. The morphological findings showed that the liver of two species of birds is located in a hepato-peritoneal cavity, and each is composed of two undivided lobes, a large right lobe and a small left one which have light brown to dark red in pigeon and dark red in ibis. The histological structu...

Mohammed H. Galhoum1, Hamza M. Eed2, Essam S. Soliman1* 

...h sample was composed of liver, intestine, and breast and thigh muscles. The study revealed a total prevalence of 35.7% (45 positives out of 126 samples). Slaughterhouse I and II, chicken farms I, II, III, IV, and V revealed prevalence up to 15.3, 23.0, 40.0, 35.0, 50.0, 45.0, and 30% respectively. Initial isolation revealed 14.2% and delayed isolation procedures revealed a prevalence of up to 21.42%. The bacteriological analysis was carried out using conventi...

Hong Yin*, Dan Yang, Ji-Jie Liu, Jing-Wei Ding and Dan-Dan Cui

...gnificantly increased in liver tissues with β-CM-7 treated. β-CM-7 decreased the fatty acid synthase (FAS) level significantly. The results suggest that β-CM-7 can change the dyslipidemia which is induced by aging. The mechanisms of the regulating effects likely tend to pass through controlling the oxidative stress and balancing the level between FAS and acetyl-CoA carboxylase (ACC).

...

Gülseren Kırbas Dogan1,*, Emin Karakurt2, Mushap Kuru3 and Hilmi Nuhoglu2

...tions. Six calves were delivered to the Department of Pathology at the Kafkas University Faculty of Veterinary Medicine between 2017 and 2019. These calves comprised one with anencephaly, one with diencephalic syndrome, one with schistosoma reflexum, two with anasarca, and one with nasal and calvarium openings. After necropsy, samples were taken from the organs, foreseen and routine pathological examinations were performed. Following these procedures, the calv...

A.H. Alqhtani1, A.S. Alharthi1, N.J. Siddiqi2, S. Zargar2 and A.M. Abudabos1*

...may cause some degree of liver damage as indicated by the release of AST and ALT in the serum.

...

Mensah Gertrude Dzifa1, Christian Larbi Ayisi2,* and Elliot Haruna Alhassan1

... effects of the diets on liver histology were studied. Three experimental diets were formulated to contain shea meal as a substitute for fish meal at 0%, 25% and 50%. The diets were designated as SNM0, SNM 25 and SNM 50 to reflect the inclusion level of shea meal. Two hundred fry of O. niloticus (initial weight of 0.82g) were obtained from Water Research Institute of Ghana (WA center) and transported to the Spanish Laboratory of University for Development Stud...

Kanakuntla Sandhyarani*, Dhoppalapudi Madhuri, Yadala Ravikumar 

... surface of pericardium, liver, intestines, air sacs, kidneys and ureters. Microscopically, tissue sections show urate crystal deposition in parenchyma of the organs along with infiltration of inflammatory cells. Incorporation of low protein diets, jaggery mixed water, supplementation of B complex and electrolytes helps in the control of gout.

Keywords | Gout, Poultry, Pathological lesions, Treatment 

...

Jie He* and Ren Yang

...roup. Rat model of whole liver ischemia-reperfusion injury was established according to Pringle’s method. Results showed that compared with propofol group and vitexin group, levels of serum ALT, AST and LDH in propofol + vitexin group were reduced (P < 0.05), apoptosis index was reduced (P < 0.05), Bcl-2 protein expression was increased (P < 0.05), Bax protein and caspase-3 protein expression was decreased (P < 0.05). In conclusion, propofol ...

Sajjad Khan*, Naila Chand, Abdul Hafeez, Nazir Ahmad 

...elative weight of heart, liver and gizzard while no significant effect was observed on pancreas and lymphoid organs. Significantly high (P<0.05) villi height (VH), low crypt depth (CD) and high VH:CD was recorded at 1.5% GA in different parts of intestine. Similarly, count of E. coli, Salmonella and C. perfringens was significantly low in ileum, caecum and colon. It was concluded that supplementation of GA at 1.5% resulted in significantly (P<0.05) impro...

Fatma Desouki Mohammed Abdallah

...ressing, carcass, heart, liver, gizzard, and spleen) weight. SPSS packages used for calculation descriptive statistics, correlations and principal component reduction method. The results showed that Bartletts test of sphericity is highly significant (P = 0.000 **) for the three lines. Three principle components were able to explain 82.193% (53.927, 15.188, 13.078 for PC1, PC2, PC3 respectively) of the total variance in the eight variables of the high body weig...
Ilvir Khabibullin1*, Ruzel Khabibullin1, Irina Mironova1, Lyalya Musina2, Elmira Akhmadullina1, Victoria Morozova1 
...rt muscles, lung tissue, liver and kidneys, where immunity and blood cells develop. Although the swimming test at the beginning of the experiment showed that mice and hamsters had approximately the same indicators of physical endurance, by the end of the experiment, the swimming time of the experimental group animals was significantly longer. The animals receiving pantocrine turned to be stronger. Their interval time increased by 267 seconds (Р≤0.05) while...

Fan Da1,3, Zheng-Yong Wen1,2*, Xiao-Dong Wang4 and Yu Luo5

...he highest expression in liver. Two-week fasting significantly decreased while refeeding dramatically increased the hepatic pvucp2 transcriptions. These findings suggested that fish UCP2 proteins are highly conserved and they might play important roles in maintaining energy homeostasis and reducing reactive oxygen species.

...
Maha Khalil1, Gamal Shams2, Hosny Abdel Fadil2, Nagah Edrees2, Mostafa Abonorag1, Nasser El-Sabbagh3, Eman A. Ahmed4*
El-Kholy, K.H.1*, Tag El-Din H.1, Seham N.E. Seleem1, A.M. El-Shhat2
...ive weights of duckling, liver and yolk sac, leg length, relative leg length, and yolk free body weight. However, such interactions were significant for hatchability and Tona Score. The highest values of leg length and duckling body weight/duckling length ratio produced from eggs dipped in nutritive solution were recorded at 17 and 31 d of embryonic ages, respectively. According to the results, it can be concluded that in-ovo dipping in 0.15% of SV solution, e...

Samah Samir, Amal Awad*, Gamal Younis 

...mortality in people with liver cirrhosis. The goal of this study was to explore the prevalence, virulence-related genes (edw1, cds1, qseC and pvsA), and antibiotic susceptibility profile of E. tarda in Nile tilapia collected from Egyptian fish farms. Between December 2019 and March 2020, 250 Nile tilapia were collected from five fish farms located at Dakahlia governorate. Organ tissue samples from liver, kidneys, gills, skin...

A. Samy1*, H.M.A. Hassan1, Fatma T.F. Abd-El Ghany2, Shama H. Morsy2 

...d carcass percent, while liver, heart, kidney, giblets, and spleen percentage were not affected. When curcumin or garlic extract were added at 200 or 400 ppm, Improved the antioxidants status by enhanced total antioxidant capacity also, significantly (P<0.05) enhanced hepatic antioxidants enzyme (superoxide dismutase, catalase, and glutathione peroxidase) compared with the control. Slightly (P>0.05) decreased in malondialdehyde of all treatments compared...

Wael Felefel1*, Mohamed EL-Beskawy2, M. F. El -Dakroury3, Mohamed Morsi Elkamshishi4, Eman Sayed Mohammed5 

...e it improved kidney and liver function tests in addition to the velocity of killing ticks with injection.

Keywords | Doramectin, Fipronil, Hard Ticks, Stray dogs, ROC curve  

...

Ouedraogo Oumar1,2, Tianhoun Denté Fidèle2,4*, Séré Modou3, Kaboré Adama2, Tamboura H. Hamidou2 and Belem Adrien Marie Gaston4

...ans (70.28%) followed by liver (17.57%), kidneys (8.10%) and heads (4.05%). Following the inspection of all the animals during the study period, the urban commune of Koudougou received a total of 1,029,600 CFA francs in slaughter fees. In addition to the considerable losses in animal protein, the financial losses linked to the seizure of organs affected by tuberculosis were evaluated at 206,949.968 CFA francs for butchers without any compensation during the sa...

Md. Serajul Islam1,2, Hongxin Wang1,2,*, Amer Ali Mahdi1, Mohamed Ismael Ahamed2, Zaixiang Lou1 and Fu An Wei3

...PH, and FRAP) of muscle, liver, hard shell, bone, and skin from grass turtle (Chinemys reevesii) by direct QUENCHER procedure. The results showed that the highest ABTS capacity was found in cooked muscle at 10 min (110.133± 4.153 g trolox Eq./kg). On the other hand, DPPH and FRAP capacity were found in cooked muscle at 20 min which were 68.966±0.937 and 37.437±1.027 g trolox Eq./kg, respectively, and raw liver

Aiman Al Mufarji, Abd El-Nasser Ahmed Mohammed* 

...lasma glucose, proteins, liver and kidney functions and minerals values. The results indicated that organic M. oleifera leaves contain protein (28.28%), carbohydrate (47.82%), fat (7.57) and fiber (28.35%). In addition, fatty acid profiles were saturated fatty acids (3.76%), unsaturated fatty acids (3.79), monounsaturated fatty acids (2.39%), polyunsaturated fatty acids (0.76%) and trans fatty acids (0.64%). Upon supplementation to ewes, M. oleifera leaves cau...

Mei Zhao1,2, Xiaoqin Zeng1, Wancai Xia1, Baoping Ren3,4, Hao Feng1, Fan Wang1, Qihai Zhou5,6* and Dayong Li1,7*

...ribed as assistance in delivery from the other females and resident male within one male unit. During each of the two births, the one-male unit’s resident male patrolled the area to keeping it secure. After birth, other members of the unit showed intense interest in the neonate. Adult females are more skilled and efficient in handling infants than sub-adult females. Our results will serve to advance our understanding of this important life history event ...
Zayed Mohammad Ali I.1*, Mona Mohamdy1, M.F. Shehata1, Nasser Ghanem2
...ght (49.11 vs. 46.21 %), liver percentage (1.74 vs. 1.39%) and percentages of edible parts (2.60 vs. 2.14%). Our results indicated that animals rose under semi-intensive system has more fat content in their eye muscle linked with increased expression of CPT-1 gene compared with animals rose under intensive system. This could be due to free movement which increased fat mobilization into muscle tissue through up regulation of CPT1 gene required for oxidation of ...

Barirah Rehman Talpur1, Zaheer Ahmed Nizamani1*, Imdad Hussain Leghari2, Mansoor Tariq1, Aisha Rehman3, Shahnawaz Kumbhar1 

... effects of fluorosis on liver and kidneys in rabbits and broilers. Sixteen rabbits and sixteen broilers of four weeks age were divided into four subgroups each were given 0mg (control),50 mg, 100 mg and 200 mg Sodium Fluoride /liter in water daily for 18 days. The clinical signs and mortality were noted. Blood was collected at days 0, 5, 10, 15 and 18 of experiment, for evaluation of liver and kidney functions. Dose and tim...

Hany M.R. Elsherif1, Ahmed Orabi2, Hussein M.A. Hassan3, Ahmed Samy3*

...ercentages of birds. The liver, heart, gizzard, and spleen were unchanged (% of body weight). Birds fed diets enriched with SF or SP had considerably (P<0.05) longer and wider guts than the control group, and scored zero in intestinal lesions scale. The addition of SF or SP were significantly enhanced (P<0.05) the lactobacillus count when compared to the control, while the quantity of Clostridium perfringens intestinal colonization was not exist. When OA...

Tri Untari1*, Sitarina Widyarini2, Michael Haryadi Wibowo1, Marla Anggita1 

...ed ginger to the chicken livers and kidneys. Antibody titers in group I, II, III and IV were determined as HI (log)2 average and were recorded 3.81, 2.91, 3.13 and 0.95, while the geometric mean titers (GMT) were 13.9, 8.6, 7.5 and 1.9 respectively. The unvaccinated groups (V, VI, VII) exhibited 0 and 1 as HI (log)2 and GMT respectively. There was a significant difference between the measured antibody titer of group I and other groups (p<0.05). No histopa...
Asmaa Khamis1, Osama Abdalla1, Mohamed Hashem2, Noha Abdelnaeim1*
... 17 and 32 of the trial, liver specimens were gathered for estimation of malondialdehyde (MDA), antioxidants, apoptotic markers, cytokines, and histopathological changes. Our results revealed a significantly increased MDA, caspase-3, p53, tumor necrosis factor-α, interleukin (IL)-1β, IL-18 and, IL-10, and a significant decline in glutathione and superoxide dismutase in the CCl4 group. However, intoxicated groups treated with PN and PM showed marked ...
Mohamed Lebdah1, Sahar Abd El Rahman2*, Ahmed Attia3, Reham Karam2, Naglaa Fathy Saeed Awad1, Mohamed Ibrahim El Bagoury1
...ages in brain, congested liver, spleen, brain and muscles besides greenish content of the gizzard. The histopathological examination of lung, brain, liver, and trachea of these diseased quails revealed non-suppurative encephalitis, perivascular cuffing, congestion of hepatic sinusoids, degenerative changes in the hepatic cells and interstitial lymphocytic aggregations in the liver and foca...
Ahmed Mohamed Elmahdy1*, Naglaa Mohammed Alkalamawy2
...ction was measured using liver enzymes activities (Aspartate aminotransferase (AST), Alanine aminotransferase (ALT), alkaline phosphatase (ALP), g-Glutamyl transferase (GGT) and total bilirubin, also the levels of Cholesterol, Triglycerides, HDL-cholesterol, LDL- cholesterol and VLDL-cholesterol were also estimated. The degree of renal protection was measured using creatinine, urea, sodium, potassium, also the levels of total protein, Albumin and Globulin were...
Luu Huynh Anh1, Huynh Tan Loc2, Nguyen Hong Xuan3, Le Minh Thanh1, Trinh Thi Hong Mo4, Ly Thi Thu Lan5, Nguyen Trong Ngu1*
... densities in the heart, liver, and spleen of chickens treated with MHH6 and PR2 phages were greatly decreased in infected chickens. After 98 days, the body weight of birds from the E. coli-infected groups treated with MHH6 and PR2 phages was lower than individuals in non-E. coli-infected groups (1,313-1,324 g/bird) but higher and significantly different from those in the PC group (1,172 g/bird). The majority of commercially important traits in chickens improv...

Samia Azad1, Iram Liaqat1*, Riffat Iqbal1 and Uzma Rafi2

...opathological changes in liver, kidney and intestinal tissues of Rohu (Labeo rohita) exposed to sub lethal concentrations of heavy metal cadmium (Cd). CdCl2 was used as cadmium (heavy metal) source. Five concentrations of CdCl2 (0.2, 0.4, 0.6, 0.8 and 1.0 ppm of Cd) were tested in glass aquaria having 35 Rohu fingerlings in each. After exposure for six week, sections of intestine, kidney and liver were excised and studied hi...

Abdul Majid1*, Farah Naz1, Nasrullah Laghari1, Sanaullah Abbasi1, Sham Lal2 and Safdar Ujjan3

...signing the novel drug delivery vehicles along its already published potential application.

...

Nkana Kontchiachou J. Gwladys1, Kouamo Justin2, Vemo Bertin Narcisse3*, Mweugang Ngouopo Nathalie4, Wang-Baa Temoa Christophe1, Awantu Christian Funwi1, Semi Yam Alphonsius1, Kenne Noubissie Christèle5, Tendonkeng Fernand5

...ological sections of the liver and kidney showed that their structures were not affected, following the green anise supplementation. Hence, the feed supplementation with green anise powder at 0.50% in guinea pigs boosted their immunity without side effects on the body functions.
 
Keywords | Green anise, Guinea pigs, Haemato-biochemical parameters, Kidney and liver histology, Supplementation
Sara Mohamed Hemeda1, R.H. Sayed2, Hani Hassan1, Sheima A.E.2, Hassan Aboul-Ella3, R. Soliman3*
..., fast, and easy to be delivered to end-users immunochromatographic lateral flow kit (LFK) has been developed for the detection of β-lactams antibiotic residues in dairy milk. The developed LFK is based on a competitive immunochromatographic format using anti-antibiotic-specific polyclonal antibodies. Specific artificially induced active acquired polyclonal antibodies production were performed in female New Zealand rabbits against the following β-la...
Aiman Al Mufarji1, Abd El-Nasser Ahmed Mohammed1*, Rashid Al Zeidi2, Haitham Al Masruri3
...ponses, metabolites, and liver and kidney functions. M. oleifera supplementation with a rate of 50 and 100 g to stressed ewes especially during high ambient temperatures and in subtropics is recommended.
 
Keywords | Blood, Heat stress, Moringa oleifera, Metabolites, Plasma
...

Xing Lu1, Mahmoud A.O. Dawood2, Fan Wu1, Hua Wen1, Wei Liu1, Juan Tian1, Ming Jiang1, Li-Juan Yu1, Xiang Li3, Ning Xu3 and Hong-Wei Liang1*

...ipase (lpl) genes in the liver of Chinese soft-shelled turtle (P < 0.05). All the above results indicated that appropriate dietary L-carnitine supplementation could improve growth performance, increase muscle protein content, reduce serum TG concentration, and induce the antioxidant- and lipometabolism-associated genes expression in Chinese soft-shelled turtle.

...
Dalia M. Aboelhassan1*, Inas S. Ghaly1, Noha E. Ibrahim2, Nermeen M. Shaffie3, Mariam G. Eshak1, Aboelfetoh M. Abdallah4, Ibrahim M. Farag1
...lpha; and COX-1 genes in liver tissues, as well as the expressions of mdr1a and COX-1 genes in kidney tissues are evaluated. In addition, the histological architectures of these organs are examined. Bisphenol A (BPA) treatment causes over-expressions of the above mentioned genes, and induces massive damage to the histological architectures of liver and kidney tissues. In contrast, FCE treatment with different doses (3.3 g/Kg...

A. El-Shemy1*, Hoda M. Mekky2, M. A. Bosila2, A. M. Allam1, Kh. M. Elbayoumi2, M. M. Amer3 

...mic losses. We collected liver samples from three duck farms representing Muscovy and Pekin breeds at ages ranging from 2 to 4 weeks and located in two Egyptian governorates between August and October 2018. The affected ducks were suffering from a short course of nervous signs, and mortality was high, reaching 75% within 3–4 days. Implementation of one-step reverse transcription polymerase chain reaction (RT-PCR) for processed li...

Lin Li1,2, Pingsheng Ye1, Xi Chen1, Shuping Yan1 and Yuanshu Zhang1*

...is study was to evaluate liver metabolism adaptation to high-concentrate diet-induced milk fat depression (MFD). Six Saanen dairy goats were randomly divided into 2 groups and fed either a high-forage (HF) diet or a high- concentrate (HC) diet. The high-concentrate diet caused lower milk fat content and milk fat yield, namely induced MFD. While, the net hepatic TG production (portal vein - hepatic vein) significant increase in the HC group (P<0.01) and it w...
Muhammad Kashif Iqbal1*, Khalid Mehmood2,4, Shakeel Ahmed3, Fazul Nabi4, Muhammad Arif Rizwan1, Muhammad Kaleem1, Mushtaq Ahmed1, Abdul Waheed1 and Jiakui Li5
... ALT and MDA contents in liver, whereas decreased the antioxidant enzymes (SOD; GSH-Px) and ALP values in thiram group, while these values were found close to normal range in FK228 group as compared to control group in response to FK228 treatment. In conclusion, VEGF and Flk-1 genes play an important role in the formation of avascular growth plate, whereas FK228 can heal lameness and avascularized growth plate in broiler chickens. So, it is effectual through r...
Rida Haroon Durrani1, Ali Ahmad Sheikh1*, Masood Rabbani1, Muti-ur-Rehman Khan2, Aneela Zameer Durrani3, Salman Ashraf1, Muhammad Anas Naeem1, Muhammad Usman3 and Tauqeer Mahmood4
...ect of oro-nasal phage delivery on bacterial population. As prophylaxis, oral phage delivery via drinking water and feed resulted in a significant (P ≤ 0.05) reduction in bacterial numbers with a mean log101.43, log101.17, log101.92 and log101.625 on 3rd and 6th dpc, respectively. The least reduction was seen in the birds that received cocktail intranasally showing log100.85 on the 3rd day. As a delayed treatment, oral de...

Muhammad Kashif Maan1*, Rohma Shabbir2 

...nce of cyst in lungs and liver upon radiographic examination. Rhinotomy approach was used to enucleate the Cyst. There was no postoperative complication after enucleation of the Cyst.

Keywords | Exopthalmia, intraorbital hydatid cyst, proptosis, Rhinotomy 

...

Omnia Mohamed Khattab1*, Hala Kamel Abdelmegeed2, Mohamed Mahmoud Mashaly1, Mervat Hamdy1*, Naglaa Hagag1, Ayman Hamed3, Hanan Aly Fahmy3, Essam Ibrahim4, Momtaz Abdelhady Shahein2, Elsayyad Mohamed Ahmed2

...-PCR. The presence of 16 liver and spleen samples out of 20 (80%) from aborted fetuses were positive for EHV-4, but all were negative for EHV-1. Virus isolation trial for EHV-4 were done, eleven samples out of 20 (55%) on the CAM of ECE were positive. The virus glycoprotein B (gB) fragment (580pb) was amplified in selected isolates using the nested PCR (n-PCR), sanger sequencing of gB from three isolates with phylogenetic analysis reveals the full identity bet...

Hakan Kececi1*, Yasin Ozturk2, M. Bahaeddin Dortbudak3, Seda Yakut4, Gurdal Dagoglu5 and Merve Ozturk1

...ange was detected in the liver and kidney tissues of the rats in the experimental groups. Both hematological and serum biochemical values (Ca, P, TBIL, ALT, AST, ALP, Urea, and Creatinine) were within the physiological limits in all groups. Consequently, in light of the obtained data, it was observed that the rats were not exposed to any toxic effect even when they consumed a stomach full of cocklebur fruit at once.

...

Eman A. Al-Shahari1,2, Eman R. ElBealy3, Abdelhalim A. Alkhazendar4 and Abeer A. Alm-Eldeen4*

... to deterioration in the liver structures and functions due to oxidative stress and the reduction in the oxidative damage’s tolerance. Quercetin, a flavonoid has the ability to face the oxidative injury through its antioxidant activity. Therefore, the present study was designed to investigate the possible role of quercetin in modulating liver’s function and structure in aged male rats. Forty eight male albino rat...

Aysam Fayed1, Mohga A Ibrahem2, Soha A. Hassan3, Mohammed Abdalla Hussein4*, Tamer Roshdy1  

...using blood samples, and liver tissue samples were used to determine glucose, insulin, leptin, TC, TG, HDL-C, ALT, AST, MDA, TNF-α, PCO. The HFD administrated rats resulted in increased total body weight, glucose, insulin, leptin, cholesterol, triglycerides, MDA, ALT, AST, TNF- α and PCO levels, as well as SREBP1 gene expression, according to the findings. However, our findings revealed a significant reduction in HDL-C, GSH, CAT and PON 1 enzyme le...

Mutassim Abdelrahman1, Ibrahim Alhidary1, Majdi Bahaddi1,2, Mohsen Alobre1,3, Riyadh Aljumaah1 and Rifat Ullah Khan4, *

...ghtered and rumen fluid, liver, kidney, and meat were collected for mineral analysis by inductively coupled plasma optical emission spectrometry. Results indicate that there is no significant difference (P >0.05) between the concentration of all the elements in all lambs’ tissues, except for the concentration of aluminum in kidney and rumen fluid, as well as Mn in rumen fluid. Moreover, Mn concentration in rumen fluid was significantly (P < 0.05) d...
Muhammad Sajid Hamid Akash1*, Hina Sharif1, Kanwal Rehman2, Sumbal Rasheed1 and Shagufta Kamal3
...arsenic concentration in liver using HG-AAS technique. ATO exposed rats showed a significant elevation in serum glucose, reduction in serum insulin, rise in insulin resistance and alteration of carbohydrate metabolizing biomarkers when compared with unexposed rats. Arsenic concentration was found to be significantly high in liver tissues of ATO exposed rats. Contrarily, RSV was found to be effective in regulating normal glyc...

Abdulkhaliq A. Al-Janabi1*, Mohammad S. Alsalami1, Arkan B. Mohammed1, Abdulkhaliq A.R. Al-Douri2 

...ced the growth rate, and liver enzymes, and reduced their lipid profiles, suggesting it would be a beneficial dietary supplement for rabbits.

Keywords | Omega-3, Polyunsaturated fatty acids, Dietary supplement, Albino rabbits, Animal feeding. 

...

Shailendra Sharma, Smriti Shrestha, Naresh Pandey and Laxman Khanal*

...lactating adult female delivered higher grooming to the troop members, while the sub-adult male received more grooming than others. We conclude that the nature of disturbance rather than the number of visitors affects social bonding among the captive langurs. 
 
Novelty Statement | This study categorized the zoo visitors’ disturbance into different levels and tested its effects on the grooming behavior of captive langurs...
Irfan Shahzad Sheikh1, Syed Haseeb Shah1, Niamatullah Kakar2*, Mohammad Masood Tariq1, Muhammad Essa Kakar3 and Muhammad Zahid Mustafa1
...a positive impact on the liver enzymes such as alanine aminotransferase (ALT) and aspartate aminoransferase (AST) on day 42. A non-significant effect was seen on hematological and biochemical profile of liver and kidney of broiler chicken on days 14th and 28th. In conclusion, the study showed significant synergistic effect of TP and OXY on the Hb, RBC and liver enzymes such as ALT and AST ...

Hafiz Qaisar Yasin1*, Dora Marinova2 and Muhammad Naveed Tahir3

...y and reliable service delivery.

...

Rijumoni Daimari, Silistina Narzari, Jatin Sarmah* 

...f edible viscera namely, liver, kidney, spleen, heart, large intestine and small intestine of Doom pig of Assam, India. The samples were collected from semi-extensively reared pig farms of Kokrajhar district, Assam. The approximate composition range of these edible viscera was found to be: moisture 50.67-68.47%, fat 0.47-9.85%, ash 0.16-0.92%, protein 6.85-22.36%, carbohydrate 10.18-24.65% and calorie 124.31-198.16 k/cal/100g. Among the samples the maximum pro...

Andi Hiroyuki1,2,*, Refina Sastya Qomariyuti1, Najmah Nur Islami3, Vanessa Ayu Sumirat4, Neni Anggraeni5, Mas Rizky A.A Syamsunarno2,6 

...amination and the heart, liver, white fat tissue, and kidneys were weighed. The results showed that the average heart weight (0.120 grams) and white fat tissue (0.145 grams) decreased in the KSO group, as did RBC (8.285×106/μl), WBC (2,943×103/μl) and platelets (506 ,5×103/μl), but statistically there was no significant difference in hematological parameters, body temperature, GDP, body weight and liver

Hossam Mahrous Ebeid1, Ahmed Abdelkader Aboamer1*, Amgad Ahmed Abu Elella2, Ibrahim Mohamed Khattab3, Osama Hefny Matloup1, Fatma Ibrahim Hadhoud1  

...in, urea-N, glucose, and liver enzymes showed no significant changes. DMSC supplementation increased milk energy content (MJ/kg), milk total solids, non-fat solids, protein, and lactose (g/kg) (linear; P < 0.05). In conclusion, supplementing lactating goats’ diets with a low level of DMSC might enhance the produced milk (quality and quantity) without any adverse effects.

Keywords | Dehulled Moringa seed cake, Rumen degradation, Milk production...

Zahin Anjum1*, Mubashra Tarana1, Shaista Ali1, Faryal Yousaf1, Amina Rahat1 and Sumbla Yousaf2

...three different tissues (liver, gizzard and muscle tissue) of the broiler chicken for absorption of four heavy metal contents (Cu, Zn, Pb and Ni). In addition, analysis of five electrolytes (Ca, Na, K, P and Mg), moisture content, protein, lipids and ash were carried out. The samples were obtained from five different sites of the University Campus, Peshawar- Pakistan. The Atomic Absorption Spectrometry was employed for determination of Cu, Zn, Pb, Ni, Ca and M...

Sajida Batool*, Sitara Shameem, Kainat Malik and Aneela Iram

... on the histology of the liver and kidney of mice. Forty adult male mice were randomly divided into four groups each of 10: Control group was given normal untreated feed, Direct group was fed on food pellets exposed to microwaves in oven tray directly, Glass group was given feed processed in the microwave oven within a glass container and Plastic group was given feed exposed to microwaves in a plastic container. The microwaves exposed feed of all treated group...

Zheng-Yong Wen1, 2*, Chuan-Jie Qin1,2, Bin Li1,2, Rui Li1,2 and Xiao-Tao Shi3*

...mRNA expression level in liver. Two-week fasting significantly decreased the transcription level while refeeding elevated the mRNA expression level of pvleptin in liver, suggesting leptin may be involved in regulating food intake and energy metabolism in darkbarbel catfish. These findings may expand our understanding about the evolutionary history and functional roles of Leptin in teleost, as well as lay a solid foundation f...

Bnar Shahab Hamad1, Bushra Hussain Shnawa1*, Rafal Abdulrazaq Alrawi2 

...s staining. The infected livers with hydatid cysts from the mice were processed for routine paraffin block technique. The sections of infected livers that were embedded in paraffin underwent immunohistochemistry. Several immunolabeled liver sections with anti-CD3, CD4, CD8, CD20, CD68, and caspase-3 were examined under a light microscope. The histological alterations caused by the hydatid ...

Ekechukwu Esther1, Ohanu Chinenye1, Ossai Nelson1*, Elijah Okwuonu1, Hinmikaiye Funmilayo1, Ngene Innocent1, Andong Felix1, Ikegbunam Clara2, Echude Daniel1, Ekeh Felicia1 and Odo Gregory1

...ative weights of kidney, liver and carcass cut parts. This study recommend that C. cajan be included in growing giant rats diets up to 25% of the dry matter.

...

Lobna M.A. Salem, Nashwa O. Khalifa, Marwa O. Abd El-Halim* 

...alyobia, Egypt, a lot of liver was condemned, which resulted in financial losses for affected farmers. In order to control the disease and raise farmer awareness, it is vital to implement the appropriate preventive measures.

Keywords | Fasciola species, Prevalence, Phylogenetic analysis, ITS2 gene, Public health. 

...

Saydat Saad Abd El-Megeed1, Walaa Yehia El-Sayed1*, Tarek Khamis2 

...vels, lipid profile, and liver and kidney functions. A reduction was recorded in malondialdehyde (MDA), as well as improved catalase (CAT), glutathione peroxidase (GPx), and superoxide dismutase (SOD). A reduction was found in the gene expression in the hepatic homogenate of Patched 1, hedgehog-interacting protein (Hhip-1), smoothened (SMO), glioma-associated oncogene homolog 1 (GLI1), and extracellular signal-regulated kinases 1 (ERK1). On the other hand, the...

Man Wang1 and Fengmei Yang2*

... of topoisomerase IIA in liver hepatocelluar carcinoma (LIHC) were analyzed to explore the possible mechanism of topoisomerase IIA in the development of liver cancer based on bioinformatics analysis. GEPIA, UALCAN, cbioportal and other tools were used to analyze the correlation between TOP2A gene expression and methylation, prognosis and immune cell infiltration in databases. The expressions of TOP2A gene and protein in tumo...

Maria Al Mazed1*, Md. Ashikur Rahman1 and Sk. Istiaque Ahmed2

...on of growth, lesions in liver and damages in kidney. They are also causing infertility in animals. Chronic exposure and excessive concentrations are also deleterious for the normal physiological functions of human. Consumption of fishes contaminated with toxic metals are neurotoxic and carcinogenic to blood, lungs, kidneys, bones, liver and other vital organs of human. The present review outlines the contamination of aquati...

Muhammad Bilal Munawar1, Saima Naveed1, Shafqat Nawaz Qaisrani1, Jibran Hussain2, Shahzad Munir3, Ayesha Ahmed3, Mubbashir Hussain4, Ahmad Kamran Khan5, Abdullah Jalal6 and Irfan Ahmed7*

... groups. Higher gizzard, liver and heart weight were recorded in group A and B while tibia ash, Ca and P in group H. Described results concluded that supplementing liquid phytase enhances breakdown of phytate phosphorus, phosphorus availability, digestibility, and growth performance.

...

Reda Hassan*, Bahaa Abou-shehema, Sherif Zayed, Micheal Gorgy, Shama Morsy, El-Sayed Abu El-Hassan, Mahmoud El-Gbaly, Hanaa Basuony, Ebtehal Hassan 

...alondialdehyde values in liver and significantly (P<0.05) diminished the reduced glutathione (GSH), glutathione S- transferase (GST). In addition to, dissemination of aflatoxin residue in broilers liver was detected. Nevertheless, dietary addition of HSCAS and SC, in separate and combined forms, alleviated the above-mentioned alterations. The combination of HSCAS with SC was more efficient than having them in a separate f...

Rezqita Putri Pitaloka1, Kartiawati Alipin1, Mas Rizky A.A Syamsunarno2, Gemilang Lara Utama3, Ramdan Panigoro2, Ratu Safitri1* 

...ron levels in the serum, liver, heart, spleen, kidney, and brain. The results showed that the effective dose was the combination of 75 mg/kg BW DFP and 50 mg/kg BW SWEE as an adjuvant, while 200mg/kg BW SWEE can be used as a substitute for chelators, especially in the heart. The decrease in serum and organ iron levels due to the combination of DFP and SWEE showed their ability to act as an adjuvant and substitute for chelators.

Keywords | Adjuvant, Def...

Shahrokh Mojarradgandoukmolla* and Hasan Akan
...inata. The levels of liver enzymes, lipid profile and glucose in the ethanol group increased significantly compared to the control, while these parameters were significantly improved in the groups treated with these three taxa. In the ethanol group, renal function and oxidative indices along with ESR showed a significant increase, while treatment with these three taxa could improve these parameters. These results were also supported by histological finding...

Uzma Zulfiqar1, Mahroze Fatima2, Syed Zakir Hussain Shah3*, Muhammad Afzal1, Shazia Shamas3, Sadia Roshan3, Moazama Batool4 and Muhammad Bilal5

... between the contents of liver thiobarbituric acid reactive substances (TBARS) and vitamin E level in the diet. Moreover, analysis of fatty acids profile showed decrease in saturated and monounsaturated fatty acids (MUFAs). While, polyunsaturated fatty acids (PUFAs) were increased in all vitamin E supplemented diets compared to control group. Furthermore, vitamin E level of 80.62 mg/kg was found optimum for maximum growth performance in L. rohita fingerlings, ...

Ghazala Nasreen1, Ali Hussain2, Komal Tayyab1, Muhammad Rashid3 and Sumaira Aslam1*

...;1) were recorded in the liver samples of the fingerlings of the treatment group T1, while the lowest corresponding figures were noted for the fingerlings of the treatment group T4. These values were lower than found in the control group having 10.50±0.23, 77.25 ± 1.19, 24.50 ± 0.96 and 18.25± 1.19 IU L−1 levels for the ACP, ALP, AST and SOD, respectively. The hyperproduction of the hepatic enzymes revealed dysfunction of the ...

S. Feroza1, A. G. Arijo1†, F. M. Bilqees2 and M. S. Phulan1

... histological changes in liver of chicken, experimentally induced with Ascaridia galli round worm. The postmortem examinations of infected chicken revealed histo-pathological lesions of infected liver that showed traumatic and toxic effects produced by the migrating A. galli larvae. Except on the top, central veins were not obvious. Inflammatory tracts produced by migrating larvae were prominent. Large vein with portal slugg...

S. Feroza 1, A. G. Arijo1†, F. M. Bilqees2* and M. S. Phulan1

...s viz., small intestine, liver, lungs and heart. Hemorrhagic enteritis and acute fibrinous enteritis with clotted blood, hemorrhagic and reddish spots on intestinal wall, inflammation and necrotic patches with consolidation of intestinal contents were generally observed. Infected liver showed dark red coloration. Severe congestion, chronic pneumonia, exuded in one lobe of the lung were seen, whereas, necrosis and atrophy in ...

O. A. Fabiyi

...l potential of Daniella oliveri leaves. The leaves
of D. oliveri were air dried and extracted with n-hexane, there after acetone. The concentrated extracts were
subjected to chromatography on a silica gel packed column. The nematicidal activity of the fractions were
evaluated in the laboratory using a 4x4x3 factorial experiment, while the crude extracts were tested on
Meloidogy...

Rukhsana Anwar1*, Ammara Abd-Us-Sattar1, Afifa Noor2, Kanwal Ashiq1,3 and Shah Jahan4 

...ehyde were determined in liver homogenates. The phytochemical analysis of extracts revealed the presence of many important bioactive compounds. Real-time PCR results showed that aqueous extract decreased the mRNA expression of CYP1A2, CYP3A4. The methanolic extract decreased mRNA expression of CYP2C9 and CYP3A4. Both extracts enhanced GST-specific activity, tGSH, SOD, and CAT activity in rats. It is concluded that leaf extracts of C. oppositifolia showed signi...

Laveena Shekhawat, Sheethal S* 

...he most common being the liver. Case report: A 29-year-old male presented with pain in the right upper quadrant with radiation towards the back along with abdominal fullness for 5-7 days. Physical examination and imaging investigations were performed on the patient which revealed the diagnosis. Results: The patient underwent laparoscopic deroofing procedure and the cyst was sent to pathology and microbiology sections for laboratory diagnosis. Identification of...

Eman S Ramadan, Mohamed E Ali, Mohamed A Elkhiat 

...croRNA-122 (miR-122) for liver injury detection involved in feline infectious peritonitis (FIP). Twelve cats were enrolled in this study. Cats were admitted to small animal hospital, Faculty of veterinary medicine, Cairo University. Cats were classified into six apparently healthy cats as a control group and six clinically diseased cats. All cats were exposed to clinical examination, abdominal ultrasonography, serum biochemical analysis as well as rapid feline...

Owolabi Olutunmise Victoria1*, Saka Olusola Stephen2, Olashinde Oluwaseun Ruth1, Alli Smith Yemisi Rufina3

...erous body organs (eyes, liver, kidney and testes) eventually suffer damage as a result of elevated blood glucose levels, which are a defining feature of the metabolic disorder known as diabetes mellitus. Researchers are in search for safe drugs that can bring a total recovery from diabetes. Thirty (35) male wistar rats were divided into six (7) groups of five animals each to study the antidiabetic and antioxidative properties of young Cola acuminata leaves aq...

Bashir Ahmad1*, Ali Muhammad Yousafzai2, Waqar Ali1, Ikram Ilahi1, Farman Ullah3, Saeed Ahmad1, Ayaz Ali Khan1, Umair Ahmad2 and Hafsa Maria2

...l parameters and several liver related serum parameters in paracetamol-intoxicated rabbits. Moreover, the amount of (DPPH) free radicals that garlic aqueous extract scavenged at various doses was used to determine its antioxidant capacity. There were five groups each of which contains eight rabbits as experimental animals. These groups were, group A (control animals), group B (intoxicated animals), group C (Animals treated with standard drug), group D and grou...

Shakeel Ahmed Tunio1, Muhammad Naeem1*, Atique Ahmed Behan1, Asmatullah Kaka2 

..., kidneys, and weight of liver of lambs in group B was recorded significantly (P<0.05) higher than the lambs of group A managed under intensive and semi-intensive management systems respectively. Based on the present study, it was concluded that weight gain, body length, chest girth and height at withers were significantly increased in the lambs of group B kept under a semi-intensive management system as compared to lambs in group A reared under intensive m...
Farid S. Nassar1,2, Abdulaziz M. Alsahlawi3, Mohammad A. Al-Mahaish4, Ahmed O. Abbas1,2*, Abdulaziz A. Alaqil1, Nancy N. Kamel5
...tic increasing yields of liver, abdominal fats, and intestines were recorded with the increased levels of MWM. The carcass breast yield and the water retention capacity and the shear force of the broiler meat were linearly and quadratically (p < 0.05) increased, while the thawing and cooking loss of meat were decreased (p < 0.05) in response to the increase in the dietary MWM levels, up to 6%. Furthermore, some physiological aspects of the broilers, such...
Shaker Al-Suwaiegh
...lasma proteins, glucose, liver enzymes and minerals parameters. The results indicated that Azolla pinnata contain protein (32.83%), crude fiber (13.6%), ether extract (1.17%) and ash (3.89%). Upon feeding, replacement diet with 20.0% Azolla pinnata caused significant increase in feed efficiency and body weight gain. In addition, the plasma metabolites (total protein, globulin, and urea) and minerals (calcium, phosphorus, magnesium and potassium) were improved ...

Aamir Mushtaq1*, Fatima Habib2, Umar Farooq Gohar3, Abdul Malik4 and Mobasher Ahmad2

...matocrit, creatinine and liver enzymes (SGOT, SGPT and TB) in mice. However, it significantly (P ≤ 0.05) increased the level of ALP in mice but on the other hand it lowered the blood glucose and cholesterol levels significantly along with increase in body weight of mice. It is concluded that P. anisum methanolic extract has a broad therapeutic index and does not produce considerable liver, kidney and blood toxicity. So, i...

Shabana Noureen1, Shamaila Asad2, Saad Ullah3, Iqra Shafique Abbasi4 and Shakeel Ahmad5*

...ithin four weeks after delivery and last for years if left untreated. To describe a detailed case study on the treatment of postpartum depression. AB design was used to report a detailed case study on postpartum depression. Cognitive behavioural therapy was used to treat the symptoms of postpartum depression. After the short treatment of only six weeks, the client learned to manage the symptoms that she was experiencing for the past two years. The study is hig...

Aiman Al-Mufarji, Shaker Al-Suwaiegh, Abd El-Nasser Mohammed*

... and metabolic profiles, liver enzymes, and minerals. The results indicated that ewes suffered from thermal stress during the study and the stress was alleviated due to M. oleifera supplementation. The body weight of ewes (p<0.05) and lambs (p>0.05) were higher in M. oleifera group compared to the control one. Ovarian structures’ development was higher in M. oleifera groups if compared to the control group. M. oleifera supplementation resulted in s...
Seyedmohammad Karimi1, Mohammad Darvishi2*, Mohammad Barati3, Ramin Hamidi Frahani4, Mohammad Hassan Kazemi5
...s harmful effects on the liver. Melatonin and N-acetylcysteine, two drugs that have previously been shown to protect the liver with their antioxidant properties, may reduce the hepatic toxicity induced by Remdesivir. Given that few studies have been performed on the role of oral melatonin and N-acetylcysteine on reducing the hepatic adverse effects of Remdesivir, we decided to conduct this clinical trial study. In this doubl...

Hussein Jabar Jasim1*, Amer Murhum Al-Amery2

...ive Fasciola spp. in the liver and gallbladder. The biochemical results showed statistically significant increases in the serum total bilirubin, creatinine, and active serum enzymes ALT, AST, ALP, and GGT. In contrast, the serum total albumin showed a significant decrease in infected buffaloes. Moreover, the results of the gross pathological examination revealed that cirrhosis and paleness of the liver with multiple abscesse...

Esam A Razin1, Hassan Sobhy2, Tarek R. AboElnaga1, Asmaa A. Darwish1*, Rasha S. Mohammed1

...s were obtained from the liver, kidney, heart, lung, spleen, and brain on the 49th day, stained, and histopathologically examined. Although, both treatments presented a significant improvement (P<0.05) in their parasitological and clinicopathological results, DAG suffered from lower levels of GR than BG, and its organs microscopical examination clarified severe lesions similar to TG. While, BG clinicopathological parameters and histopathological results wer...

Sadaf Aman1, Fouzia Tabssum2, Ali Hussain3, Shamsa Jabeen1 and Javed Iqbal Qazi1*

...ogical parameters of the liver and intestinal tissues for the fishes fed with plant based feeds added with probiotics. Conclusively, fish production can be enhanced with the addition of probiotics in the feed derived from plants.

...

Muhammad Shahid1*, Muhammad Idrees1, Afza Rasul2, Iram Amin1 and Samia Afzal1

...ng a key role in chronic liver disease all around the globe. Currently, in Pakistan, it is a huge burden on health and the economy, affecting about 6 to 8% of the overall population. HCV is dependent on the lipid metabolism of the patient to replicate and then disturb the blood cell count and liver enzymes to ultimately damage the liver. To distinguish the potential HCV patients from healt...

Abdirahman Barre*, Karanja D Njuguna, Bebora Lilly Caroline and George Chege Gitao

...epatomegaly with nodular liver lesions 79 (49.3%), enteritis 5 (3.1%), haemorrhages and congestion of visceral organs (lung and kidney) 6 (3.7%). Histopathology of sero-reactors revealed; cellular infiltration in lymph node 9 (5.6%), hypoplasia of lymphocytes 6 (3.7%), collapse of alveoli 5 (3.1%), oedema, congestion 4 (2.5%), fatty degeneration in liver 3 (1.8%) and haemorrhages in kidney1 (0.6%). In conclusion, brucellosis...

MARIUM ASLAM, MUHAMMAD JAVED, FAIZA AMBREEN* & FARIHA LATIF

...roxidase activity in the liver and kidney of Catla catla. To check the concentration based effect, C. catla were exposed, separately, to 96-hr LC50 of zinc and its sub-lethal concentrations viz. 2/3rd, 1/4th and 1/5th of LC50 for 30 days at constant laboratory conditions. After 30-day, the fish were sacrificed and their liver and kidney were analyzed for peroxidase enzyme activity. Change in activity of peroxidase enzyme in ...

Subramaniyam Suresh, Saravanakumar Marimuthu*, Prashanth D’Souza 

...iglycerides (mg/dL), and liver marker enzymes (IU/L) viz. aspartate aminotransferase (AST), alanine transaminase (ALT), and gamma-glutamyl transferase (GGT). Results revealed that 4% FCM was numerically improved on week 1 (0.11), week 2 (0.46), week 3 (0.56), and week 4 (0.54) as compared to baseline in PTF supplemented group. Milk fat (%) was also significantly (p < 0.001) improved on weeks 2, 3 & 4 as compared to baseline in PTF supplemented group. Se...
 
 USMAN AHMAD*1, AMTUL JAMIL SAMI1, MADEEHA KARAMAT1, MADEEHA KHALID1, FAIZAN NAEEM2 & MUHAMMAD JAMIL YOUSAF
... Transdermal drug delivery seems to be overwhelming and alternative to other means of drug delivery via oral or intravenous. To treat the diabetes mellitus and to get rid of the traditional injection treatment which is a painful process and can cause infections and allergy, the drug delivery through the skin cells can substitute only if the skins cells permeability for the drug is inc...

Ubaida Hussain1,2*, Amtul Jamil Sami1*, Shazia Rafique3*, Muhammad Idrees khan3 and Ahmad Ali Shahid3

...on which can progress to liver cirrhosis, fibrosis, hepatic cancer, and death. The goal of this work was to assess the cytotoxicity and in vitro inhibitory activities of local medicinal plant Azadirachta indica (A. indica) extracts on expression of NS3 and NS5A nonstructural proteins of HCV 3a genotype. Owing to the fact that HCV patients can develop HCC, plant extract has also been tested for cytotoxic activity. Colorimetric analysis was done to determine the...

Enas K. Abo El-Maged, Azza H. El-Salakwy, Safia A. El-Gamal and Gehn Allam

...ll term normal vaginal deliveries were used as a control group. Their age ranged from 17-42 years (mean = 29.31). The age at marriage lies between 16-36 years. All samples were tested for HPV-DNA by polymerase chain reaction (PCR) amplification using one pair of general primers which allowed for the amplification of HPV types 16, 18, 31, 33, 52, & 58. These primers were designed to amplify E6/E7 gene junction sequences. Twenty nine out of 100 (29%) samples...

A. A- E. Abo-Elkhier1, K. S. E. Abdel-Wahab2, M. A. Ali3, M. A-H. El-Sayed4, N.A-K. Saleh5 and A. A. Atef6

...IgM positive full term delivered women were tested for REV Ag and HEV RNA. Among 120 aborted women. 2.5 (3/120) of them were positive result with anti-HEV IgM. Anti-HEV IgG, HEV RNA and HEV Ag. also 11.7 % (14/120) of them gave positive result with anti-HEV IgG. HEV RNA and HEV Ag. and 5.8 % (7/120) or them were positive for anti-HEV IgG only. Also 13 of 120 (10.83 %) full term delivered women were anti-HEV IgG positive only...

Saad Zaghlou El-Damrawy1, Reda Ali Hassan2*, Ahmed Maher Bakhaty1, Adel M. Nasr2, El-Sayed A. Abu El-Hassan2  

...tiveness of two distinct liver tonics (Silymarin and Choline chloride) against aflatoxin B1 (AFB1), as well as the impacts of AFB1 on the growth performance, liver weight, haematological, and serum biochemical responses of broiler chicks. Six nutritional treatment groups with equal numbers of birds each were created. In a randomized complete block design experiment, each group contained 100 birds in five repetitions and was ...

Muhammad Arshad Iqbal*, Aamir Ghafoor, Irfan Ahmad, Muhammad Ijaz 

...ughtered at d35 and d42, liver, spleen, intestine, and ceca were collected to observe organ colonization. Use of Bacillus amyloliquefaciens as feed additive decreased the shedding pattern of S. Enteritidis and Cl. Perfringens and may pave way for safe poultry rearing and addressing public health concerns associated with AGP.
 

...

Shaimaa A.Tawfik2,3, EL S.T. Awad1*, Hoda O.Abu Bakr1, Amira M.Gamal-Eldeen4, Esmat Ashour2, Ismail M.Ahmed1  

...amination in sections of liver, kidney and heart tissues were confirmed these findings. In liver tissues, DOX resulted in an observable induction in CYP3A4 and MRP-1, while CSO/DOX showed an inhibition in both proteins. c-MYC was dramatically decreased in DOX group, while CSO/DOX group restored cellular c-MYC. CSO/DOX group resulted in a remarkable inhibition in the tumor suppressor miRNA (let-7a) compared to DOX-induced ex...

Rahma Boukarine*, Leila Hamdi and Kamel Khelili

... pathological changes in liver and kidney tissue were characterized by sinusoidal and tubular dilatation, hemorrhage, hepatocyte necrosis and glomerular degeneration, the effect of ESAE was effective in modified these damages into semi normal.To conclude, xylene administration induced hepatotoxicity and nephrotoxicity in wistar rats, while the combination of this solvent with rocket aqueous extract (Eruca sativa) attenuated this toxicity thanks to its antioxid...

Atena Azarniush1, Majid Moghbeli2*, Farshid Kafilzadeh1, Mohammad Kargar1 and Hooshang Jamali1

... by GenRay (China) and delivered to pGS vector. The vector was transferred to DH5α, then the gene was subcloned onto pHT43 shuttle vector and transformed into the Bacillus subtilis WB600. The vector containing the cloned gene was induced within the WB600 by IPTG. The SDS-PAGE also indicated the successful expression of IL-11 in B. subtilis. A band of about 22 kD corresponding to the recombinant protein was observed in positive sample. This research demon...

Nawfal Hammadi Jasim1, Yasmeen Jassim Mohammed2 , Jala Amir Salman Alahmed1, Majdy Faisal Majeed3* 

...acrificed, and blood and liver tissues were collected for biochemical and histological analysis . Results: Comparison to the Control Group, the ratio of ALT in the blood serum significantly increased in groups 1 and 2 of MPH-treated rats, meanwhile, the ratio of AST remained unchanged significantly in Group 1. In the liver, MDA and GSH-PX rates were significantly increased (P≤0.05) in 1 and 2 groups compared to the 3 gr...

Meltem Kızıl1*, Ali Rişvanlı2, Murat Abay3, Tarık Şafak4, Mehmet Akif Kılınç5, Öznur Yılmaz6, Burak Fatih Yüksel1 and İbrahim Şeker1

...cording to the mode of delivery. The study was carried out with 20 Holstein cows and 20 calves born from these cows. Blood samples were taken from cows and calves in all groups during birth, after drinking colostrum from calves and on the 15th, 30th, 45th and 60th days after birth in 10 ml tubes. The levels of the aforementioned molecules in these blood samples were determined by ELISA method. Feeding with colostrum led to a decrease in the irisin levels in th...
Umara Amir ud Din1, Waqas Ahmed Khan1*, Khurrum Shahzad1,2, Basharat Ali3, Misbah Hussain1,4 and Fazli Rabbi Awan4
...protein cholesterol, and liver enzymes (ALP, ALT, and AST) were measured for all subjects. Genotyping for ACE (I/D) polymorphism was done by PCR assay. Statistical analysis showed that subjects with DN had higher (67%) frequency of ID genotypes and the ID genotype carriers also exhibited higher levels of creatinine (6.2±3.9 mg/dL) and urea (99±41 mg/dL). Moreover, logistic regression analysis also indicated that ACE ID genotype carriers had a 2.5...

Zahra Abdulameer Al-Zayadi1, Hana Kadum Shanan1, Al Salihi Karima Akool2

...al features were seen in liver and kidney sections from the control and other mice groups before various treatments. The various treatment groups revealed diverse histopathological changes compared to the control groups. Various histological features were also seen in low, moderate, and high-dose Sc-RE treatment groups, accompanied by regeneration related to the treatment dose. Severe damage comprising necrosis of the hepatic cells, renal tubules, congestion, ...

Munir Ahmad1, Abdul Ghaffar1, Riaz Hussain2* and Rifat Ullah Khan3*

...higher concentrations of liver biochemical profile, biomarkers of kidneys, triglyceride, glucose, and cholesterol in fish treated with pesticide. Histopathological examination showed renal tubular degeneration, widening of Bowman’s space and necrosis in kidneys. Different histopathological lesions in liver of treated test specimens including edema, hemorrhages, atrophy of hepatocyte and hepatocyte having eccentric nucl...

Saba Yasin, Kausar Imran, Komal Mukhtar, Muhammad Amir Iqbal and Nabila Roohi*

...ct of paint chemicals on liver and renal profile in occupationally exposed household painters was evaluated in this study. For this purpose, 25 healthy male controls and 25 male painters were selected from Lahore, Pakistan. Unpaired Student “t” test was applied to analyse the parameters for statistical interpretation. There was significant increase in Alanine Aminotransferae (ALT), Alanine Phosphatase (ALP) and total bilirubin in painters as compar...

Amr N. El-Shahat1*, A.M. Abdul Azeem1 and Mohamed H.M. Abd el Megid2

...he antioxidant status in liver and heart tissues with indicated inhibition of lipid peroxidation by reducing the level of malondialdehyde compared to HCD-fed rats. The results concluded that BLE may have an effective role in reducing high cholesterol levels.

...

Skenndri Safae1*, Charrat Nadia2, Jmiai Mehdi3, Nassik Saadia1 

...rial isolation following liver translocation revealed the existence of a number of bacterial entities. Most of them were foodborne pathogens, in fact, all the groups displayed close levels of infection by Escherichia coli, Staphylococcus aureus, Salmonella spp, and Staphylococcus spp; And Yersinia enterocolitica was also detected on one of the farms. Broiler performance can be affected to varying degrees by biosecurity levels on farms. Higher biosecurity level...

Salvator Minani1,2*, Eric Nsengiyumva1, Anatole Bigirimana1,2, Arnaud Cubahiro1,2, Dieudonné Ntakirutimana1,2 and Vénuste Bizoza1,2

...lence of fascioliasis by liver inspection in slaughtered ruminants at Muyinga slaughterhouse. The liver of each slaughtered domestic ruminant was inspected, palpated and incised to look for flukes in the liver bile ducts. Statistical analysis was done using R software. A total of 265 domestic ruminants including 69 cattle, 190 goats, and 6 sheep were inspected to determine the presence of ...

Zaki Al-Hasawi1* and Reda Hassanine2

...water, sediment and fish liver samples from the unpolluted site, while their corresponding concentrations were significantly high in the polluted site. Mean concentrations of other metals (Mn, Fe, Ni, Cu, Zn) in water, sediment and fish liver samples from polluted site were significantly much higher than those from the unpolluted one. In contaminated fishes from polluted site, mean levels of blood biochemical parameters, ser...

Zaki Al-Hasawi1* and Reda Hassanine2

...water, sediment and fish liver samples from the unpolluted site, while their corresponding concentrations were significantly high in the polluted site. Mean concentrations of other metals (Mn, Fe, Ni, Cu, Zn) in water, sediment and fish liver samples from polluted site were significantly much higher than those from the unpolluted one. In contaminated fishes from polluted site, mean levels of blood biochemical parameters, ser...

Yoshio Hamano1*, Yasuji Kurimoto2 

... skeletal muscles or the liver. However, it is unclear whether a combination of these additives functions concomitantly or synergistically to improve meat quality. The present study was conducted to determine the single or combined effects of LIP and AWP on growth performance and free amino and fatty acid profiles in chicken muscle obtained under different feeding states. At 14 days of age, chicks were allocated into four groups and fed diets supplemented with...

Kazi Afsana Homayra Orchy1, Mst. Antora Akter1, Nelema Yesmin1, Md. Moshiur Rahman Khan1, Marzia Rahman2, Md. Mahmudul Alam1* 

...y sample. Regarding the liver and kidney functions, the serum levels of liver enzymes (ALT, AST and ALP) and kidney function biomarkers (creatinine, BUN) showed a significant increase in burn patients of the saline-treated control animals, whereas, the animals treated with hPRP exhibited the normal range of these functional biomarkers. On the basis of morphology, histopathology, and biochemical analysis, it can be concluded...

Walaa I. Mohameden1, Haidy G. Abdel-Rahman2, Ibrahim M. Hegab3* 

...th, skin conditions, and liver and kidney functions. Significant (P < 0.05) increases in plasma proteins, zinc, and copper were recorded, while malondialdehyde, TNF-α, and MMP-9 significantly (P < 0.05) decreased. Furthermore, buffalo calves showed significant ( P < 0.05) increases in both ingestive and locomotor activities, while grooming and lateral recumbency significantly (P < 0.05) declined. Mineral supplementation had a favorable effec...

Mohamed Mahrous Amer1*, Hanaa Sayed Fedawy2, Hoda Mohamed Mekky2, Khaled Mohamed Elbayoumi2, Ahmed Ali El-Shemy3, Mohamed Abd El-Rahman Bosila2

...ematological parameters, liver and kidney functions were also recorded. Colistin+ Doxycycline combination (Doxyforte®) was used to control the infection. Clinically, site of infection was appeared red, swollen accompanied with increased skin thickness, postmortem lesions in the 3rd day post infection with s.c. yellowish suppurative exudates, pericarditis and perihepatitis were prominent E. coli infected with hepatic subcapsular hemorrhage mostly in S. aure...

Khalid M. Al-Syaad1,2

...xposure causes decreased liver, kidney, and testicular functioning, as well as significant histopathological abnormalities. Therefore, the present study investigated the toxic effect of CC and the protective effect of Propolis aqueous extract on CC-induced toxicity in male rats. A total of 24 Wistar albino rats were included in this study, divided into four groups; each group containing 6 rats and administered the treatment doses orally by gavage for 28 days. ...

Weijun Chen1*, Shiyang Gao1, Ping Sun1, Xiaohui Sun2, Yongbin Wei1, Jingyang Chen1 and Jialong Chen1

...e growth performance and liver health of common carp (Cyprinus carpio), we formulated three isonitrogenous diets: the control diet (5.8% crude lipid, Control diet), the high-fat diet (10.8% crude lipid, HF diet), and the NaBT diet (10.8 % crude lipid and 0.1% NaBT, NaBT diet). Each diet was assigned to triplicate tanks (100 L) with 24 fish (14.52±0.08 g) in each tank. Experimental fish were fed twice daily for 8 weeks. The results showed that fish growt...

Hafiz Muhammad Arsalan1, Amina Arif1 and Muhammad Khalil Ahmad Khan2*

...), complete blood count, liver profile, renal profile, lipid profile, serum electrolytes were evaluated in CML and control groups. Our study reported that no significant difference in biochemical profile among treated with Nilotinib or Imatinib tretated groups while in comparision to control group, a marked difference was observed. Antioxidant biomarkers i.e. MDA, SOD and CAT were augmented in control group as compared to CML treated groups. Decreased GSH leve...

Peter Amuguni Mbato*, Wanzila Usyu Mutinda, Noah Kipkoech Maritim, Nicholas Edwin Odongo 

A.M. Abdul Azeem1, A.N. El shahat1* and Mohamed H.M. Abd el Megid2

...idant activities against liver injury induced by bisphenol A (BPA) in male rats. In this work, Citrus paradise peels extract used for reduction of sodium selenite (Na2SeO3) to reduce Se ions to Se0 confirmed by changing the colour of the solution from light yellow to red. The synthesized SeNPs were characterized by Ultraviolet-visible spectroscopy (UV-Vis spectra), Fourier transform infra-red (FTIR) spectroscopy analysis and Transmission Electron Microscope (T...

A.M. Abdul Azeem1, A.N. El shahat1* and Mohamed H.M. Abd el Megid2

...idant activities against liver injury induced by bisphenol A (BPA) in male rats. In this work, Citrus paradise peels extract used for reduction of sodium selenite (Na2SeO3) to reduce Se ions to Se0 confirmed by changing the colour of the solution from light yellow to red. The synthesized SeNPs were characterized by Ultraviolet-visible spectroscopy (UV-Vis spectra), Fourier transform infra-red (FTIR) spectroscopy analysis and Transmission Electron Microscope (T...

Mohammed A. El-Sayed1*, Mahmoud H Hatab2, Heba AEM Assi3, Nashaat S Ibrahim2, Hisham M Saleh2, Waheed AA Sayed2, Birgit A Rumpold4 

... small intestine, heart, liver, gender organs, spleen, and bursa of Fabricius of quails when compared to diet A. The LBW, relative carcass weight, and measured organs of the diet A group were significantly impacted by the interaction of dietary treatment and HS, whereas these traits had no or minimal effects on the diet B and diet C groups. The HSP70 gene transcription level was highest in birds exposed to cyclic HS and fed control diet A, and lowest in birds ...

Abnet Mekonnen1*, Kadir Abderehman1 and Feti Seyaka2

...s are metabolized by the liver and excreted by the kidneys. Monitoring vital signs continuously during anesthesia will provide early warning of potential problems and emergencies that may be averted by appropriate and quick corrective actions.

...

Dhurgham K. Seger1, Rahman H. H. Al Qasimi2, Azhar A. Jaffar3, Salah H. Faraj4, Ahmed I. Ateya5* 

...tics including heart and liver weight alongside recovery rate. Meanwhile, there was no significant effects between polymorphisms of SSTR1 and the remaining carcass traits including live weight, carcass weight, clearance percentage, and spleen and kidneys weights. This study highlights the possible efficiency of using SSTR1 as candidate marker for carcass traits in sheep. 

...

H.A. El-Nagar1, A.M. El-Hais2, M.S. Mandouh2, W.M. Wafa1*, A.H. ABD El-Aziz, K.A. Attia4 

...in, immunity, kidney and liver functions, and antioxidant status of female newborn Friesian calves. This administration is considered a good strategy for raising dairy calves in dairy farms.  

...

Salma Jameel Askar 

...ological alterations and liver functions parameters in albino male rats and to determine the effects of Beetroots ethanolic extract in alleviation these alterations. Eighteen male albino rats were used, and they were divided into three groups of six animals each: G1, which received a dose of distilled water as a negative control; G2, which received a dose of meloxicam at 1.3 mg/kg.BW was a positive control, and G3 received a dose of meloxicam and beetroots eth...

Tehreem Iqbal1, Roheela Yasmeen1* and Faheem Hafeez2

...T and ALP were linked to liver injury and a higher weight in the liver were observed in BPA treated rats as compared to the control group. Similarly, an increase in blood parameters were recorded in BPA treated rats followed by post -treated rats and pre- treated group. It was concluded by the study that BPA have pronounced adverse effects in the exposed animals particularly in BPA and cinnamon post- treated rats as compared...

Asmaa A Darwish* 

...dney function tests, and liver enzymes concentrations and a significant (P<0.05) decrease in IL-10, antioxidants, total protein, albumin, glucose, total lipids, cholesterol, minerals, electrolytes, and trace elements concentrations. The DG hemogram clarified a significant (P<0.05) microcytic hypochromic anemia accompanied by neutrophilic leukocytosis and lymphocytopenia, and their iron profile characterized by a significant (P<0.05) hypoferremia, hyp...

Mustafa M. Khalaf*, Rana A. Salih 

... consequences, including liver damage associated with oxidative stress, its therapeutic usage is restricted. The most potent antioxidant among flavonoid chemicals is quercetin, the aim of this study was to evaluate the protective effect of quercetin against cyclophosphamide. An explanation of quercetin’s hepatoprotective effects against cyclophosphamide-induced hepatotoxicity. Twenty-eight male Westar rats (that weighed 200–250 g) were chosen at ra...
Qiangsheng Wu1, Yumei Yin2, Hui Gao1, Baoding Chen3, Jianjun Yu2, Jian Zhang4, Donglai Zhu5, Fang Liu6, Guohong Ge7 and Ya-Mei Dang8*
...ere compared to 8 normal liver tissues to screen out the significant abnormal expressed genes. The potential interactions and mechanisms of these genes in promoting hepatocellular carcinoma were analyzed through bioinformatics analysis. The results showed that the functions of these 1495 differently expressed genes enriched in cell cycle, oxidation-reduction and drug metabolic process. Additionally, the top 10 core genes of these differently expressed genes we...

Nusrat Habiullah1*, Shah Nawaz Kumbar1, Fahmida Parveen Samo1, Shamusuddin Bughio2, Asghar Ali Kamboh3, Burirah Rehman Talpur1 

...ecropsy examination, the liver and kidney samples were collected for gross and histopathological examination. The mild clinical signs like reduced feed and water intake, and weight loss in group C, D, E and F was noted; whereas diarrhea, muscular tremors, and lethargy were observed in group C and D. Significantly increased (p <0.05) GGT, bilirubin, creatinine and uric acid levels were recorded in C and D (lead toxicity groups), as compared to control group...

Ali Mosa Rashid Al-Yasari1, Zahid I. Mohammed2, Haider S. Almnehlawi3,4, Ali F Bargooth5, Nawar Jasim Alsalih1, Huda F. Hasan6*, Mohenned A Alsaadawi1 

...this investigation, we delivered fresh milk from Arabian camels to adult male rats that had been given STZ to induce diabetes. Three groups of ten adult male Albino rats each were created at random from the thirty total animals. Control group was given ordinary food and free water, the STZ-Diabetes group received one (ip) injection of streptozotocin (40 mg/kg), and the STZ-diabetes+Camels’ Milk group received a STZ injection (40 mg/kg) along with daily (...
Saad Ibrahim Al-Sultan1, Mariam H.E. Khedr2, Ahmed S. Abdelaziz3, Mostafa M. Abdelhafeez4, Tamer Mohamed Gad5, Sabry Mohamed El-Bahr6,7*, Sherief Abdel-Raheem1,8 and Hesham A. Khalifa3
...e offal including round, liver, kidney, and tongue in samples collected from Zagazig slaughterhouse, Egypt and Al-Ahsa slaughterhouse, Saudi Arabia. Dietary intakes and potential health risks associated with the consumption of camel meat and edible offal among Saudi and Egyptian populations were additionally calculated in a comparative way. The obtained results indicated that edible offal including liver, kidney and tongue h...

Shafi Muhammad1, Bibi Nazia Murtaza2, Aftab Ahmad1, Muhammad Shafiq3, Nurul Kabir4 and Hamid Ali1*

...e presence of persistent liver inflammation characterized by the expression of different inflammatory molecules including Interleukin-17 (IL-17). The progression of chronic liver ailments (fibrosis, cirrhosis) towards hepatocellular carcinoma (HCC) is determined by the distortion produced in the normal structure of liver. Pakistan bears the second highest numbers of hepatitis C virus (HCV)...

Muhammad Shahid Nisar1*, Ahmad Kamran Khan1, Ghulam Fatima2, Irfan Ahmed4, Khizar Sami Ullah2 and Syeda Amber Hameed2,5

...zzard, all other organs (liver, heart, intestine, pancreas, lungs, spleen and kidney) resulted significantly difference (p<0.05) and affected with FW supplementation. Broiler fed with 25% and 50% FW affected positively (p<0.05) to lymphocytes, granulocytes, red blood cells, hemoglobin, mean corpuscular hemoglobin and mean platelet volume while D3 also resulted positively in results of mid-range absolute count. While birds fed D4 (75% FW) resulted signifi...

Rini Widyastuti1*, Rangga Setiawan1, Nurcholidah Solihati1, Siti Darodjah1, Kundrat Hidajat1, Mochamad Ali Mauludin2, Alkaustariyah Lubis3, Mas Rizky Anggun Adipurna Syamsunarno4, Sigit Prastowo5, Takdir Saili6, Arief Boediono7

...of pregnancy, signs of delivery, and weaning of lamb. The results showed that less than 50% of farmers lacked awareness about the length of heat and the signs of early pregnancy. The majority of the participants immediately carried out mating of the estrus dairy goat and more than 75% treated the pregnant animal and prepared a proper place for delivery. A small proportion of <25% managed and weaned the kids. Farmers mated...

Hamdy Abdala El-Nagar1, Abdelaziz Mohamed Elhais2, Ayman Hassan Abd El-Aziz3, Wael Mohamed Wafa1, Mohamed Sobhy Elsayed Farrag2, Moataz Ibrahim Badawy1, Safaa Elsayed Salah Atia2

...s, on growth efficiency, liver function, kidney function, total antioxidant capacity, and immune response of Friesian calves from 7 to 105 days of age as an experimental period. Newborn male calves (n=20) weighing 37.92±0.63 kg were divided into 4 groups, five calves/group. The first group (G1, control) included animals without treatment. During the whole suckling period each animal in G2, G3, and G4 daily received milk supplemented with propolis (5 g),...

Shafqat Ullah1, Asad Ullah2*, Imad Khan2, Rafiq Ullah1, Raheela Taj3, Fatima Syed3, Shumaila Gul4, Faiza Khan5, Ibad Ullah Jan6, Muneeb Islam7 and Sumaira8

... of different organs i-e liver, gizzard, heart, pancreas, and proventriculus etc. showed significant (P≤0.05) results in each of selenium-supplemented groups. Overall, 0.3 mg/kg (Basal diet) of selenium showed better results with respect to the positive control group.

...

Ahmed Al-Hasnawi*, Wafaa Kadhim Jasim

..., GSH, and MDA levels. a liver sample was also taken for each of the aforementioned groups to be examined histopathological. According to the findings, azathioprine dramatically decreased the MCV, MCH, and MCHC blood test results as compared to the control group receiving only regular aloe vera, as well as the levels of the function liver enzymes GST and GSH. In contrast to the control group, azathioprine treatment led to a ...

Raed Hussein Salih Rabee1, Yahya Sabah Abdulameer1, Walla Farhan Obed1, Noor R Abady1, Adnan Mansour Jasim1*, Firas Hussein Albawi1, Mohammed Jasim Jawad2, Ahmed Samir Abukhomra3

...fically in the thigh and liver. The docking study confirmed inhibitory activity of Cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) an enzyme responsible for the metabolism of antibiotics. Additionally, berberine demonstrated antibacterial effects against E. coli, as well as anti-inflammatory and antioxidant properties. Furthermore, histopathological examination of the intestinal broiler received BBR showed improvements and restore tissue near to normal....

Afshan1, Asad Ullah2*, Imad Khan2, Rafiq Ullah1, Tahira Tayyab1, Fatima Syed3, Raheela Taj3, Shumaila Gul4, Faiza Khan5, Ibad Ullah Jan6, Syed Weqas Ali7 and Assad Ullah8 

...ples were collected from liver, muscles, kidney and whole blood. The whole blood was centrifuged for further analysis. The redox status and thyroid hormones were measured through commercially available kits. The current study resulted that selenium supplementation improved(P≤0.05) the catalase level in the liver and muscles which fight against the free radical and reduce oxidative stress. In the blood serum the catalase a...

Dan Song1,2, Ming-Juan Ge3, Jie Li1,2, Yi Jiang1, Xiu-Mei Kong1, Jiao-Jiao Xu1, Xu Ji1,2, Rui-Xin Shi1 and Qin Zhao1,2*

..., catalase (CAT) in mice liver were measured; while SOD and MDA contents and activity of T-AOC, CAT, Na+-K+-ATPase, Ca2+-Mg2+-ATPase, pyruvate kinase (PK) and phosphofructokinase (PFK) in mice brain were evaluated. In the results, G. straminea ethanol extract markedly enhanced hypoxia tolerance in mice. It attenuated hypoxia-induced oxidative stress by reducing MDA levels (in liver and brain), and elevating SOD (in
Mahmoud M. Bayoumi
...accine production, the delivery methods, and the essential compositions added to the mRNA vaccines to enhance efficacy and stability. This information ultimately would pave the way to better thinking to combat viral infectious diseases.
...

Oghenebrorhie M. Oghenochuko1,4*, Olubukola T. Adenubi3, Olusola L. Ajayi3, Fakilahyel M. Mshelbwala3, Johnny O. Olukunle3, Samson A. Rahman3 and Godfrey N.O. Ezeri2

...sponse, humoral changes, liver and kidney function and histopathology of some visceral organs were examined. Proximate composition of the bulb was determined. Onion bulb revealed presence of carbohydrate (7.82%), protein (4.48%), crude fiber (1.68%), iron (0.5mg/l), magnesium (210mg/l), flavonoids (0.46%), saponins (0.28%), tannins (0.95%). PCV, Hb, RBC and WBC were increased in all treatments but values were higher in bath treatment for RBC (3.0×1012/L)...

Usama Mahalel1, Barakat M. Alrashdi1, Ibrahim Abdel-Farid1, Sabry El-Naggar2, Mohamed Hassan3, Hassan Elgebaly1 and Diaa Massoud1,4*

...d increased the relative liver weight. Treatment with M. forsskalii extract after CCl4 injection restores the weights of mice to the normal range and reduced the relative weight of the liver. Mice that were injected with CCl4 exhibited elevation in the liver enzymes; aspartate aminotransferase (AST) and alanine aminotransferase (ALT), reduction in the cholesterol content, and altered the a...

Rasema Majeed, Alaa Kamil Mahmood* 

...les (CNPs) can improve delivery and bioavailability of encapsulated agents such as GEE. The aims of this study to evaluate the protective effects of ginger ethanolic extract, chitosan nanoparticles, and ginger ethanolic extract loaded with chitosan nanoparticles (GEE-CNPs) against DNA damage and pancreatic histological changes in dogs with alloxan-nicotinamide-induced diabetes. histological analysis was assessed. The results showed that first group (Control ne...

Ibrahim l , Madiha Salah and Ikuta 2, Kazuyoshi

...t organs including lung, liver and brain tissues with high sensitivity and specificity. The sensitivity and specificity were 71% and 100% for Sysmex avian influenza kit and 86% and 33% for Sysmex influenza MB kit. Thus, Sysmex avian influenza kit was shown to be a potentially useful tool for the direct and rapid detection of H5N1 in clinical specimens due to its high specificity. Additionally, an advantage over the other kit is specifically reacting with virus...

El-Kenawy, A. A. and El-Tholoth, M. S.

...lung (4), kidney (3) and liver (3)). Hyperimmune serum was prepared against reference LSDV (Ismailyia88 strain). Immunofluorescence (IF), immunoperoxidase (IP) techniques and polymerase chain reaction (PCR) were used in our study. Chorioallantoic membranes (CAMs) of embryonated chicken eggs (ECEs) were inoculated with Known previously isolated and identified LSDV of 104 8 EID5d0.1 ml for virus follow up in these CAMs by using IF and IP techniques and PCR. The ...

Abo Elmagd l , Enas K.; Abdel-Wahab l , Kouka S.; Alrasheedy l , Zeinab E. and Khalifa2, Ahmed S.

...y t012 months. All the deliveries were vaginal. Neither the infants nor the mothers had a history of high risk exposure to percutaneous virus transmission. Commercial ELISA kits for IgG, IgM, IgA anti-HCV epitopes and RT-PCR kits were used according to kit instructions. Dot ELISA for detection of HCV antigen in infants PBNINC lysates was an in house test. Previous exposure to HCV infection indicated by antibodies to the HCV six epitopes was detected in 8/61 (1...

Fadia M. Attia and Hanaa H. A. Gomaa

...ic status in HCV chronic liver diseases. 50 patients with chronic hepatitis C were enrolled in this study. Qualitative and quantitative PCR by real time PCR was done to determine the level of viremia before induction of therapy. In addition, complete blood count, prothrombin time and liver function tests were performed. The results showed that leucopenia and thrombocytopenia are more frequent in HCV patients with moderate de...

Eman, M. Abd El-Mottaleb.*; Ahmed, S.A."; Maysa, H.M.*; Salem, S.A.* and M. M. El-Shenawy

...wabs and tissues (bovine liver, kidney, lymph nodes and lung) for BEFV isolation and propagation on Vero, BHK21 cell lines and baby mice. Identification was done by both Indirect Fluorescence Antibody Technique (IFAT) on tissue culture and inoculated mouse brain, while immunoperoxidase technique was done on bovine lung. Haematological examination revealed leucocytosis accompanied with neutrophilia (immature form) and lymphopenia. Histopathological examination ...

Divanildo Outor-Monteiro1,2,3*, José António Silva2,3,4, José Luís Mourão1,2,3, Victor Pinheiro1,2,3

... relative organ weights (liver, kidney, lung and heart), decreased hind part proportions and lower cooking loss values. Furthermore, the hind legs of these rabbits had a greater proportion of muscle and less bone, along with increased luminosity and reduced redness. In conclusion, production systems exert influence on specific carcass and meat characteristics.
 
Keywords | Rabbit, Housing system, Slaughter-age, Carcass, Meat
...

Farid S. Nassar1,2, Osama A. El-Sayed3, Saidi Ouassaf4, Ahmed O. Abbas1,2* 

...e carcass yield, breast, liver, and spleen increased substantially (p < 0.05). The plasma total protein and triiodothyronine hormone levels were remarkably (p < 0.05) enhanced by adding FS to broiler meals. At the same time, the concentrations of alanine transferase, aspartate transferase, and uric acid were significantly (p < 0.05) lowered. Additionally, the triglycerides were dramatically (p < 0.05) decreased while the high-density lipoprotein co...

Sajjad Khan*, Naila Chand, Abdul Hafeez and Nazir Ahmad

...mproved weight of heart, liver, gizzard, pancreas, bursa, spleen and thymus was recorded for the groups studied. Significantly higher (P<0.05) VH, lower (P<0.05) CD and higher (P<0.05) VH:CD in duodenum, jejunum and ileum were recorded in synbiotic group D followed by C, E and B. Similarly, supplementation of synbiotic in group D and Bacillus subtilis group C resulted in complete eradication of E. coli, Salmonella and C. perfringens from ileum, caecum...

Lingang Dai1,2,3, Xiang Chen1,2,3, Jiajin Huang1,2,3, Jiali Xu1,2,3, Meimei Xiao1,2,3, Jiajing Chen1,2,3 and Yong Ruan1,2,3*

...(P<0.01), whereas the liver of female goats was significantly higher than that of male goats (P<0.01). Polymorphism analysis of the PGAM2 gene showed that there were polymorphic loci in the 3’UTR (2435A→G), and there were significant (P<0.01) or highly significant (P<0.05) differences in some traits between the GG and AG or AA genotypes. Conclusion: The production performance of male goats is better than that of female goats in F3 genera...
Geeta Moolchandani1, Jaiperkash Moolchandani2*, Nasima Iqbal3
Syed Mohsin Turab4, Muhammad Kashif5 and Lubna Farooq6
...ion (23.4%), premature delivery (25.5%) and intrauterine growth retardation (16.6%). Overall, 95.2% neonates were identified to have one or more of these contributing factors. Stratified analysis showed that over all neonates of female gender were associated with having more frequency of HIE. Maternal anemia was found to be significantly associated with the occurrence of HIE. The frequency of HIE risk increased with increasing maternal age. Lowest the serum pH...

Sena’a M. Hussein1,2, Raffal A. Omar3* 

...o enhance the targeted delivery and prolonged release of local anesthetics. The purpose of this study was to assessment the effect of single and repeated lumbosacral injection of liposome carrying lidocaine in comparison with lidocaine hydrochloride. A total of 24 male local breed dogs were divided randomly into the lidocaine group that received 4.5 mg/Kg of 2% lidocaine and liposome group which received the same dose of lidocaine carried by liposome. Pinprick...

Xiangmei Chen, Burie Bao* and Mo Degema

...ats or the weight of the liver, kidney, or pancreas. After STZ modelling, the blood glucose levels of rats noticeably increased. However, the blood glucose values of rats decreased substantially due to camel placenta treatment from the 4th to the 6th week. Camel placenta dramatically reduced the serum HbALc and GLUC3 content in hyperglycaemic rats. Dry CPP had a down-regulating effect on the levels of SGLT2 and GLUT2 protein, SGLT2 mRNA and GLUT2 mRNA in the k...

Kadhim Kh. K. Al-Khayat1*, Athmar K. A. Al-Azawi2

...ntery, 21.82% (12/55) in liver, 21.82% (12/55) free within abdominal cavity and 9.09% (5/55) in omentum with Significant differences (P<0.05).  The cyst diameters range between 7-21mm. in length and 4-10mm. in width. The PCR amplification results of 14 positive samples for NAD1 (500bp.) and COX1 (446bp.) genes and 3 isolates were squincing and submitted to GenBank under the accession numbers (LC731847.1, LC731848.1 and LC731849.1) for NAD1 gene are 100...

Eman Said El-Hadad*, Hesham Ahmed Madian, Mahmoud A.E. Hassan, Mohamed Fahmy Saad, Abdelghany M. El-Shhat, Entesar Zakaria Eliraqy

... biochemical parameters, liver and kidney function, and antioxidant markers were determined. Results showed that RBCs and lymphocyte increased, while neutrophils and Neut./Lymph ratio decreased in G2, however, Hb, PCV, RBCs, MCH, and lymphocyte increased, while WBCs, neutrophils, and Neut./Lymph ratio decreased in G3 in comparison with G1. Plasma total protein and albumin increased, while total cholesterol, triglycerides, LDL, urea, creatinine, AST, and ALT de...

Suhad Mohmmed Alrobyrai1 , Falah Muosa Al-Rekabi2*

...c drug, but it can cause liver damage when taken in high doses or for prolonged periods. Alpha Lipoic Acid (ALA) and Tempol are two antioxidants that have been shown to protect against various forms of oxidative stress and inflammation. This study explored the hepatoprotective effects of Alpha Lipoic Acid (ALA) and Tempol against subacutely repeated acetaminophen (APAP) exposure in a murine model. Fifty male Balb-c mice were divided into five groups. Groups re...

Irfan Ullah1, Asad Ullah2*, Tahira Tayyeb1, Rafiq Ullah1, Muhammad Hanif1, Faiza Khan3, Imad Khan2, Raheela Taj4, Fatima Syed4, Shumaila Gul5, Muhammad Sadeeq6, Muneeb Islam7, Arsalan Khan8 and Khudija Ghani9

...norganic selenium on the liver enzymes, kidney function and changes in biochemical parameters of broiler chicken under dexamethasone (DEX) induced stress. The day old, two hundred (n=200) chicks were bought from commercial hatchery and randomly divided into five groups with eight replicas(n=5) in each group. Broiler chickens were fed with starter and finishing commercial corn based basal diet (BD) with different doses of inorganic Selenium (Se) powder. Group-A...

Tayfun Karatas1*, Betul Apaydın Yıldırım2 and Serkan Yıldırım3

...ced toxicity in gill and liver of rainbow trout (Oncorhynchus mykiss). CMN exposure led to increase in aspartate aminotransferase (AST), serum alanine aminotransferase (ALT) and malondialdehyde (MDA) levels, and reduction in superoxide dismutase (SOD), catalase (CAT) activities, glutathione (GSH), total immunoglobulin (T. Ig), and white blood cell (WBC) levels. Moreover, CMN exposure led to degeneration, steatosis, and necrosis in live...

Rondius Solfaine1, Faisal Fikri2, Salipudin Tasil Maslamama3, Muhammad Thohawi Elziyad Purnama4, Iwan Sahrial Hamid5*

...ectively mitigated lung, liver, and duodenal damage by reducing the expressions of TNF-α and IL-1β in mice.
 
Keywords | Canine coronavirus, TNF-α, IL-1β, Lactobacillus acidophilus
...

Huda S.J1*, Nasr T.M1, Mohanad A. Al-Bayati2

...O4 NPs by the targeted delivery Nanohemosome. As well as leading to improved cell health and increased RBC production.
 
Keywords | Hemorrhagic anemia, Cobalt ferrite nanoparticles, Nanohemosomes, nano-medicine, Toxicity, Rabbit
...

Ghaith Z. Hasan Al-Askari *, Eman H. Yousif Al-Taee

...tological finding in the liver is severe and generalized hepatocellular necrosis, which revealed congestion, hemorrhage, and degeneration of hepatic cells. Some sections of the kidneys show vacuolation of mesangial cells in the glomerular tuft. Muscles of treated rats revealed severe histopathological changes under stress from both doses of toxic cholecalciferol, also showing the widespread mineralization of muscle fibers. From this study concluded that both d...

Kashif Abdaal, Aneeza Batool, Muhammad Tariq Navid*, Saeed Ahmed, Asma Saleem Qazi, Waseem Safdar, Haidar Ali, Mobeen Ur Rashid, Somia Rafaqat 

...-based and plant-based delivery mechanisms have proven as more targeted and adaptable approaches to boost immune responses. Hence, it proves the vaccines as a big breakthrough in preventive and therapeutic medicine over 200 years and named “Future Medicine”. To assess vaccine safety and efficacy, scientists are now using various model animals like mice, ferrets, pigs, and nonhuman primates before using them for human trials. The other side of succe...

NAILA MALKANI*, IRFAN ISHAQUE, KHALID SHAHBAZ, RIZWAN ULLAH KHAN, ARIFA SHABBIR & ATIF YAQUB

...ps to perform kidney and liver enzymes profile and histological analysis. The results showed that the values concerning liver function enzymes were significantly altered in wild-caught fish as compared to farm raised fish. Also, significant difference was noted in serum creatinine and urea values between the two groups. Histology of liver and kidney tissues revealed signs of chronic damage...

SHAGUFTA ANDLEEB1*, ASMATULLAH2, SHABANA SHAUKAT1 & SIDRA NAWAZ2

... histological changes in liver of mice. Twenty mice (4-5 weeks old) were given oral gavages of 0.1 ml of 0.00, 31.25, 125 and 500μg/g B.W (Complete). of Metformin prepared in distilled water, for 04 weeks daily. After 24 hours of last dose, the animals were anaesthetized torecoverliver tissues following fixation in Bouin’s fluid and processing for histological preparation using different grades of alcohol and xylene...

Wesam Jasim Hansh 

...s were isolated from the livers of cows and buffaloes slaughtered in the municipality of AL-Nassiriyah abattoir during July to November 2022. Sixty Fasciola flukes including (30 from cows and 30 from buffaloes) were used in morphological study. Genomic DNA was extracted from 30 Fasciola flukes (15 from cows and 15 from buffaloes) and used to amplified the 28S rRNA gene and amplicons were sequenced. Based on the morphological study and sequences analysis of 28S...

SYED SHAHID IMRAN BUKHARI1*, IQRA AZAM1, MUDDASIR HASSAN ABBASI1, MEERAB DAUD1, NADEEM SHEIKH2, ANDLEEB BATOOL3, RABIA MAHMOOD2 & MARYAM MUKHTAR2

...traperitoneally and then livers were extracted after 3, 6 and 12 hours. All the samples were processed for gel run and thermo cycler program, which revealed alterations in the expression of hepatic mRNA (IL-6) in all loads equally confirmed by the results of housekeeping gene β-actin. Gel analysis showed changes in the folds of IL-6 in hepatic mRNA compared to control. These finding led to the conclusion that Alloxan can induce an APR, which is evident by...

MUHAMMAD JAVAID AFZAL*1, FARAH JAVAID2, MUHAMMAD WASEEM ASHRAF3, SHAHZADI TAYYABA4, MAMOONA ASHIQ5 & AYESHA AKHTAR5

... for flow rate of drug delivery through a nanoneedle for drug delivery. The outflow rate is measured as 1.32 mL/min through MATLAB simulation. The measurements are verified by the Mamdani’s model and the previous research. The simulated results given in this study specifies that the fuzzy logic deliver an effective modeling presentation by showing good agreement with the parametric m...
NOREEN RAZA1*, TASNEEM A. SAQIB2, SYED NAEEMUL HASSAN NAQVI3, MUHAMMAD ZAHEER
KHAN2 & MAZHAR HIJAZI3
...fects of Lead nitrate on liver, gizzard, and kidney of Herring gull (Larus argentatus) were studied. Significant changes were observed after high and low concentrations of Lead nitrate were injected to Larus argentatus. Paraffin sections showed major alterations at high and low concentration of Lead nitrate in liver, gizzard and kidney. High concentration of Lead nitrate induced, severe dystrophy along with hepatic necrosis;...

ZAHRA NASEEM1, MUHAMMAD AMIR IQBAL1, SHAAF AHMAD2 & NABILA ROOHI1*

...cts of hypothyroidism on liver and renal parameters and effectiveness of thyroid treatment (thyroxine) on these factors in hypothyroid subjects were assessed in the present investigation. A total of 140 subjects (30 subclinical and 50 overt hypothyroid) between the ages of 15-50 years from INMOL, Lahore and 60 healthy euthyroid controls of the similar age groups from local population were recruited. Additionally, follow up studies of nearly thirty five overt h...

ADEEBA SYED1, DILAWAR HUSSAIN2, UZMA RAFI1 & SUMAIRA MAZHAR1*

...s organs like intestine, liver and kidney were collected and sections were examined under digital microscope. Pronounced histological changes like necrosis, infiltration, atrophy, shrinkage and degeneration of intestine was observed for different CPF concentrations. Kidney sections of Labeo rohita under different CPF concentrations exhibited nuclear hypertrophy, vacuolar degeneration of glomeruli, and occlusion of tubular lumen, cloudy swelling degeneration an...

MUHAMMAD NAEEM RAZA1, KALSOOM SUGHRA1* & NADIA ZEESHAN1

...tion is primary cause of liver disease that leads toward liver cirrhosis and hepatocellular carcinoma. This study designed to diagnose the prevalence of HCV genotypes circulating in Gujrat, Punjab. Blood samples of 3540 suspected patient were collected from July 2017 to January 2019 and analyzed for HCV infection by using qualitative PCR, confirmed cases were subjected to molecular genotyping on Real Time PCR (Applied Biosys...

UZMA PARVEEN1, MASROOR ELLAHI BABAR1*, NIDA BABAR2, TAHIRA MUGHAL3 & AKHTAR ALI1

...cell survival. Preterm delivery is a confused prenatal unfavorable occasion. This examination work was planned to associate relationship of G308A and -238 polymorphisms in Tumor necrosis factor alpha. We collected blood samples of 70 patients out of which 50 ladies gave untimely births and 20 ladies gave typical births. DNA extraction technique was applied. Primers were designed, amplified by PCR and RFLP were performed to identify the TNF–alpha -308 and...

Taghreed Jabbar Humadai*, Bushra Ibrahim Al-Kaisei

...of tetrodotoxin (TTX) on liver of male albino rats. At the age of 8–9 weeks and weighing 190–200 gm, 60 male albino rats were separated into 3 groups: First group of 20 rats received distilled water and regular pellets. Second group of 20 rats received weekly injections of 0.5 µg/kg b.w. by I/P route, which was equivalent to 1/20 LD50 of tetrodotoxin. Third group of 20 rats received weekly injections of 1 µg/kg b.w. by I/P route, which ...

Iqra Munir*, Farrah Iftikhar, Hira Fatima, Sunbal Khalil Chaudhari and Roha Ramash

... influenza, diabetes and liver diseases. 60% plants used to cure digestive diseases, diarrhea, cancer, inflammation, stomachache and dysentery. About 30% plants used to cure cardiovascular diseases and ulcers. The purpose of this study is to recognize wild plants gathered for medicinal purposes by the local residents of Mandi Bahauddin and to document the common names and therapeutic uses associated with these plants.

...

Ping Sheng Ye1, Lin Li2, Yu Long Wu3 and Yuan Shu Zhang1*

...ent of IGF-1 and GH. The liver and mammary gland samples were collected to observe the expression of IGF-1R and GH. The results showed that compared with the control group, the content of plasma GH and IGF-1 were decreased in the high-concentrate group, and the percentage of lactose and milk yield were also decreased. Meantime, the mRNA expression of IGF-1R in mammary gland was down-regulated in the high-concentrate group. Our results indicated that feeding wi...

Bushra AL-Khaqani, Amira Mohammed*  

...the lung (P<0.05) and liver (P>0.05). Additionally, in the BALF, RES therapy reduced (P<0.05) inflammatory cytokines including interleukin-17 (IL-17) and interferon-gamma (IFN-γ). RES increases (P<0.05) the expression of Il10 gene in the spleen, which is associated with T-regulatory and anti-inflammatory processes in the immune system. Our findings showed that RES may reduce asthma by activating anti-inflammatory genes, restoring lung barrier...

Noura K. Al-Suwailem1, Nancy N. Kamel2, Ahmed O. Abbas1,3*, Farid S. Nassar1,3 , Dalia A.A. Elsayed4, Gouda F. Gouda1,5, Hosam M. Safaa3,6

...tinine, urea levels, and liver enzymes activity were significantly (P<0.05) increased. The carcass yield and meat quality showed significant (P<0.05) deterioration in response to heat exposure. MLM administration to the basal diet significantly enhanced blood metabolite levels, hematological parameters, antioxidant activities, carcass yield, and meat quality in broiler chickens exposed to HS. Thus, we have confirmed the potentiality of using dietary MLM ...

Advances in Animal and Veterinary Sciences

May

Vol. 12, Iss. 5, pp. 802-993

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