Bacteriostatic Effect of Royal Jelly on Methicillin-Resistant Staphylococcus aureus
Bacteriostatic Effect of Royal Jelly on Methicillin-Resistant Staphylococcus aureus
Songhao Tian1*, Jinhua Li1, Jing Zhao2, Jiamin Sang1, Ruizhe Song3 and Zhaoying Guang3
ABSTRACT
This study aimed to investigate the bacteriostatic effect of royal jelly (RJ) on methicillin-resistant Staphylococcus (MRSA) and to elucidate the underlying mechanism. MRSA cultures were exposed to varying concentrations of royal jelly (RJ), and MRSA absorbance at 600 nm was measured every 10 hours to assess the impact of RJ on MRSA proliferation. SDS-PAGE electrophoresis and Coomassie blue staining were employed to assess the impact of RJ treatment on MRSA protein expression. A 5% concentration of RJ exhibited substantial inhibition of MRSA proliferation (P < 0.01), with a concentration-dependent increase in inhibitory potency. SDS-PAGE electrophoresis and Coomassie Blue staining results suggested a potential link between royal jelly and its impact on MRSA protein expression, contributing to its inhibitory effect. RJ can disrupt the normal MRSA protein expression and impede MRSA proliferation, though it doesn’t completely eradicate MRSA.
To share on other social networks, click on any share button. What are these?
