Effect of Di-n-butyl Pthalate on Oxidative Stress Parameters in Liver and Gills of Labeo rohita
Effect of Di-n-butyl Pthalate on Oxidative Stress Parameters in Liver and Gills of Labeo rohita
Iqra Jaffar, Zainab Sehzadi, Muhammad Adeel, Khalid P. Lone and Mehwish Faheem*
ABSTRACT
Phthalates are plasticizers, released from different sources, are ubiquitous in the aquatic environment. In the present study, freshwater fish (Labeo rohita) juveniles were exposed to low concentrations (10μg/l and 100μg/l) of di-n-butyl phthalate (DBP) for 7 days to evaluate oxidative stress in liver and gills by analyzing activity of glutathione-S-transferase (GST), catalase (CAT), glutathione (GSH) and by measuring lipid peroxidation (LPO). Catalase activity increased significantly in liver and gills of fish exposed to 10μg/l of DBP. Level of GSH and LPO increased significantly in gills while a non-significant decrease was recorded for GSH and GST in liver. These results showed that exposure to low concentrations of di-n-butyl phthalate are capable of inducing oxidative stress in vital organs of fish that may cause detrimental effects on the fish health.
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August 2019
Vol. 51, Iss. 4, Pages 1203-1598
