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Electrochemistry of Vitamin D and Biosensors for its Determination: A Review

Electrochemistry of Vitamin D and Biosensors for its Determination: A Review

Nargis Sardar1*, Maria Binte Sarfraz2, Sufian Rasheed3 , AKM Rezwan Sardar4 , Fahamida Zaman5, Arsalan Rasheed6,7* 

1Department of Material Science and Electrical Engineering, State Research Institute, Center for Physical Sciences and Technology Vilnius, Lithuania; 2Department of Physiology, Army Medical College, National University of Medical Sciences, Rawalpindi, Pakistan; 3HEJ Research Institute of Chemistry, Karachi, Pakistan; 4Department of Textile and Apparel Marketing, Primeasia University, Dhaka, Bangladesh; 5Department of Microbiology, Primeasia University, Dhaka, Bangladesh; 6Department of Zoology, Abdul Wali Khan University Mardan, Pakistan; 7SST (Bio-Chemistry), Elementary and Secondary Education Department (E&SED), Khyber Pakhtunkhwa, Pakistan.

*Correspondence | Nargis Sardar, Arsalan Rasheed, Department of Material Science and Electrical Engineering, State Research Institute, Center for Physical Sciences and Technology Vilnius, Lithuania; Department of Zoology, Abdul Wali Khan University Mardan, Pakistan; Email: nargis.sardar@ftmc.lt, arsalanrrasheed@gmail.com 

ABSTRACT

Vitamin D play a vital role in health, therefore, it is necessary to find a sensitive, selective as well as quick and easy technique for its determination. This review focuses on the Vitamin D investigations of electrochemical biosensors that have been conducted in recent years. According to the research, the practical use of electrochemical biosensors is attributed to the existence of UV radiation and transactivation of pharmaceutical items, food, or even human blood plasma in the detection of Vitamin D from diverse samples, including Vitamin D production in nature. Among the most commonly used electrochemical biosensors for vitamin D detection are Ab-25OHD/SPE/ FMTAD, CYP27B1/GCE, SiO2/GO/Ni(OH)2/GCE, BSA/Ab-VD2/CD-CH/ITO, BSA/Anti VD/Fe3O4 PANnFs/ITO, BSA/Ab-VD/Asp-Gd2O3NRs/ITO, 25OHD Antibody, 25OHD, 25OHD Antibody, IoT Enabled Enzyme Embossed Biosensor, Au-Pt NPs/APTES/FTO and GCN-β-CD/Au nanocomposite. The proposed electrochemical biosensors utilized in the previous publications studied were based on glassy carbon, carbon dots, or carbon paste, functionalized with the various electrochemical biosensors. Further research should be conducted on existing problems and future opportunities of the present electrochemical sensors for the determination of vitamin D.

Keywords: Vitamin D, Biosensor, Radiation, Carbon dots, Glassy carbon, Carbon paste 

 

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Pakistan Journal of Zoology

August

Vol. 54, Iss. 4, Pages 1501-2001

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