In Silico Analysis of Cu-Zn Superoxide Dismutase and Mn Superoxide Dismutase Genes in Fugu (Takifugu rubripes)
In Silico Analysis of Cu-Zn Superoxide Dismutase and Mn Superoxide Dismutase Genes in Fugu (Takifugu rubripes)
Mehtap Bayir*
ABSTRACT
Superoxide dismutases are the best-known enzymatic antioxidants because of their central role in the antioxidant defense system. In this study, the phylogeny, gene structure, and conserved gene synteny of sod1 and sod2 genes in fugu—a model organism—were determined. Maximum amino acid similarity identity was found between putative fugu Sod1 and Sod2 proteins and their orthologs from teleost fish and tetrapods. Phylogenetic clustering was seen between sod genes in fugu and their orthologs. Finally, highly conserved gene synteny was determined between fugu sod genes and their orthologs from teleost fish and human.
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August 2020
Vol. 52, Iss. 4, Pages 1225-1630
