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Treatment of Endometritis Caused by Different Types of Bacteria by Cefoperazone Antibiotic and its Effect on the Days Open and Pregnancy Rate in Dairy Cows (Field Study)

Treatment of Endometritis Caused by Different Types of Bacteria by Cefoperazone Antibiotic and its Effect on the Days Open and Pregnancy Rate in Dairy Cows (Field Study)

Yahia A. Amin1*, Alaa Eldin Z. Mahmoud2, Mohamed Sabry Aref3, Abd El-Latif Shaker Seddek4, Waleed Younis5 

1Department of Theriogenology, Faculty of Veterinary Medicine, Aswan University, Aswan, Egypt; 2Department of Theriogenology, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt; 3Department of Theriogenology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt; 4Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt; 5Department of Microbiology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt.

*Correspondence | Yahia A Amin, https://orcid.org/ 0000-0003-4075-2664, Department of Theriogenology, Faculty of Veterinary Medicine, Aswan University, Aswan, Egypt; Email: yahiaamin2030@gmail.com 

ABSTRACT

One of the most important problems on dairy farms is postpartum endometritis. It can destroy the future of dairy farms and the dairy industry since it leads to prolonged days open and prolonged intercalving intervals, resulting in involuntary culling. The current study aimed to detect the most sensitive antibiotic to different types of microorganisms responsible for endometritis and its effect on the days open and pregnancy rate. The current study was carried out on 100 Holstein Frisian cows that were not pregnant for 90-120 days after calving. The cows were classified into two groups: the first group is the normal control group (9 cows), and the second group (91 cows) is the treated group and suffered from endometritis. Samples for bacteriological examination were taken and subjected to antibiotic sensitivity tests. The most sensitive antibiotic was used for the treatment of the infected group. After the end of the treatment protocol, the herd reproduction management was applied to all treated cows. Results showed that different bacterial species were isolated (Staphylococcus, Streptococcus, Escherichia coli, and Klebsiella). The infection is either a single infection (Staphylococcus only), or a mixed infection, while the control group has no bacterial growth. Staphylococcus was the only microorganism responsible for the single infection. Infection with Staphylococcus and E. coli has a higher incidence of infections with two microorganisms, while infection with Streptococcus and Klebsiella has the least incidence of infections with two microorganisms. The results also revealed that Cefoperazone is the most sensitive antibiotic. Cows infected with mixed infections have the longest postpartum period of pregnancy, especially those infected with E. coli, and Klebsiella. It is concluded that the greater the number and virulence of the microorganisms responsible for the infection, the greater the severity of uterine inflammation and the longest postpartum period of pregnancy. Various types of bacteria are responsible for endometritis, such as Staphylococcus, Streptococcus, E. coli, and Klebsiella. Cefoperazone is the most sensitive antibiotic for the treatment of complicated cases of postpartum endometritis caused by mixed infections and high virulence bacteria.

Keywords | Endometritis, Bacterial infection, Cefoperazone treatment, Dairy cows, Days open, Pregnancy rate. 

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Journal of Animal Health and Production

October

Vol. 11, Iss. 3, Pages 234-329

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