The study is carried out on the histology and micrometrical analysis in skin of different body regions (dewlap, abdomen, scrotum / udder and thigh) of young and adult of either sex of red Sindhi cattle (Bos indicus). Skin of red Sindhi cattle showed epidermis thickness rang of 41.1-50.13 µm and dermis thickness rang of 443.97-597.05 µm in all body regions and significant (P˂0.05) in age and sex group. The epidermis possessed stratified squamous epithelium, and main cells was keratinocytes. The dermal-epidermal junction was regular with an absence of dermal papillae and epidermal ridges. Dermis layer possess dens irregular connective tissue, which consist of elastic, collagen and reticular fibers. Superficial dermal papillary layer was located beneath the epidermis, whereas dermal reticular layer deeper above the hypodermis. The papillary and reticular dermis was well developed in adult male age group with abundant areolar and dense irregular connective tissue all skin regions. Skin appendages (sebaceous and sweat gland, and hair follicle) was well developed and distributed in papillary and reticular layer in adult age group, while in young age group mainly observed at papillary dermal layer of all body regions. Sweat gland was mainly baggy-tubular shaped based on L/D ratio 7.64 to 8.3 range in all body skin regions, contain higher volume (3.2±0.1 μ 3 ×10−6 and 3.9±0.1 μ 3 ×10−6) in dewlap and thigh body region of adult age group. Whereas numbers of sweat gland / cm2 were observed more in abdomen body region of young than adult age groups and in thigh followed dewlap region of adult group than young age group.
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