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Ovalbumin-Induced Asthma in Rats is Alleviated by Resveratrol Treatment

Ovalbumin-Induced Asthma in Rats is Alleviated by Resveratrol Treatment

Bushra AL-Khaqani, Amira Mohammed*  

Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq.

*Correspondence | Amira Mohmmed, Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq; Email: dr.amirakamil@covm.uobaghdad.edu.iq  

Figure 1

The effect of RES, Ova- induced Asthma, and their combination on the number of infiltrated mononuclear cells in BALF and intraperitoneal fluid in mature male rats. * P<0.05 is the statistical threshold for group differences. A: number of infiltrated mononuclear cells in BALF. B: Number of infiltrated mononuclear cells in intraperitoneal fluid. G1: rats received only drinking water, G2: Rats orally received resveratrol 100 mg/kg, G3: Rats were induced asthma, G4: Rats received both resveratrol and induced asthma. 

Figure 2

The effect of RES, Ova-induced asthma, and their combination on lung vascular leak by Evans blue dye in adult male rats * P<0.05 is the statistical threshold for group differences. A: Amount of Evans blue stain in the lung. B: Concentration of Evans blue stain in the liver. G1: rats received only drinking water, G2: Rats orally received resveratrol 100 mg/kg, G3: Rats were induced asthma, G4: Rats received both resveratrol and induced asthma. 

Figure 3

The effect of RES, Ova-induced asthma, and their combination on the concentration of IL-17 and IFN-γ in adult male rats. * P<0.05 is the statistical threshold for group differences. A: Concentration of IL-17 in BALF. B: Concentration IFN-γ in BALF. G1: rats received only drinking water, G2: Rats orally received resveratrol 100 mg/kg, G3: Rats were induced asthma, G4: Rats received both resveratrol and induced asthma. 

Figure 4

The effect of RES, Ova-induced asthma, and their combination on Il10 gene expression in adult male rats. * P<0.05 is the statistical threshold for group differences. G1: rats received only drinking water, G2: Rats orally received resveratrol 100 mg/kg, G3: Rats were induced asthma, G4: Rats received both resveratrol and induced asthma. 

Pakistan Journal of Zoology

April

Pakistan J. Zool., Vol. 56, Iss. 2, pp. 503-1000

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