Yun-Feng Liu, Yong-Mei Guan, Dan Chen, Jia-Le Chen, Chen Jin, Wei-Feng Zhu, Lu Wu and Li-Hua Chen*
...e content alterations in paeoniflorin after application of a combination of Strychni Semen extract (SSE) and Paeoniae Radix Alba extract (PRAE) by in vitro skin permeation were observed. The penetration quantity, infiltration rate and skin retention quantity of paeoniflorin in co-administrated with SSE were increased significantly (P<0.05). In the skin and brain, the peak concentration (Cmax) and ...
Shu-Zhi Qin, Wen-Pei Ling, Mei-Fang Yin, Chun-Yu Luo and Cheng-Guo Zhao*
...the protective effect of paeoniflorin (PF) on hypoxia reoxygenation (H/R) injury and its effect on MAPK signal pathway to reveal the mechanism of PF against myocardial ischemia-reperfusion injury, in this study, the H/R model of H9C2 cells was established by hypoxia for 3 h and reoxygenation for 3 h. H9C2 cells were divided into 4 groups, the control, PF + control group, H/R group and H/R + PF group. The activities of aspartate aminotransferase (AST) and lacta...
