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Effect of Exercise Intensity on Human Immune System under Different Environments

Effect of Exercise Intensity on Human Immune System under Different Environments

Yanjie Liu

Department of Basic Teaching and Research, Yango University, Fuzhou, 350015, China

* Corresponding author:


The objective of this study was to explore the influence of exercise intensity on human immune system under different environments. Sixty physical education students were enrolled as research objects and divided into control group (normal oxygen group), hypoxia group, and high-altitude group. Each group was given the same exercise intensity. Venous blood was collected before and after each test to determine changes in Immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), IL-2, WBC, natural killer (NK) cell activity, C3, C4, CH50 and body weight. We found that the levels of IgA, IgG, and IgM in the three groups decreased; while IL-2 levels increased, and the order can be ranked as control group>hypoxic group>high altitude group (P<0.05). Moreover, WBC, C3, C4, CH50, and NK cell activity of three groups decreased, and the comparison result was control group>hypoxia group>high altitude group (P<0.05). The body weight also decreased but followed the gradation of the high-altitude group>hypoxic group>control group (P<0.05). We conclude that different oxygen environment exercise intensities have different effects on different immune functions under the basic state, and have significant and independent effects on the activities of WBC and NK cells, which can be used as for monitoring of effective immune indicators.

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Pakistan Journal of Zoology


Pakistan J. Zool., Vol. 56, Iss. 3, pp. 1001-1500


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