Identification of Ten New N-acetyldopamine Dimers from Periostracum Cicadae
Identification of Ten New N-acetyldopamine Dimers from Periostracum Cicadae
Lu Yang1,2*, Ke Zhang3 and Jin-Hui Wang1,2,4
ABSTRACT
Periostracum Cicadae is the cast-off shell of the cicada Cryptotympana pustulata Fabricius, it is a widely used animal based traditional folk medicine, it is found to have many effects including antipyretic, antiallergic and antioxidant activities. In this study, ten N-acetyldopamine dimers, named Cicadamide C1–C10 (compounds 1–10), were isolated from Periostracum Cicadae. One-dimensional NMR, two-dimensional NMR, mass spectrometry, CD spectroscopy, and chemical evidence were performed to further determine their structures. In the results, ten N-acetyldopamine dimers were isolated and their structures were elucidated. This study provides a basic reference for further biological effects study on Periostracum Cicadae.
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